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boards. 942+ pages, includes: illustrations, references, index. *****PLEASE NOTE: This item is shipping from an authorized seller in Europe. In the event that a return is necessary, you will be able to return your item within the US. To learn more about our European sellers and policies see the BookQuest FAQ section*****
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boards. 942+ pages, includes: illustrations, references, index. *****PLEASE NOTE: This item is shipping from an authorized seller in Europe. In the event that a return is necessary, you will be able to return your item within the US. To learn more about our European sellers and policies see the BookQuest FAQ section*****
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More About This Textbook
Overview
Now available in its Third Edition, Asthma: Basic Mechanisms and Clinical Management has become the reference text in asthma. This highly successful text sheds new light on the basic physiological and molecular mechanisms of asthma, how current treatments work, and how best to apply the latest knowledge to control this important disease. The Third Edition has undergone radical revision and includes several new chapters. It retains the virtues of the previous volumes by bringing together all of the recent research findings by internationally recognized experts on the causative mechanisms of asthma, including in-depth clinical aspects and therapy. The book presents an integrated approach toward the treatment of this disease with new concepts, changes in asthma management, and the development of new therapeutic agents. Asthma provides extensive references for researchers and clinicians who need to keep abreast of recent developments in this rapidly expanding field.
Key Features
• Comprehensive coverage of both basic science and clinical aspects of asthma
• Extensively referenced throughout
Audience: Researchers, teachers, and clinicians in asthma and respiratory medicine in universities, medical schools, and industry. Undergraduates and postgraduates in medicine and science.
Editorial Reviews
From the Publisher
"This book is clearly written...each chapter is extensively referenced and as up to date as possible...essential reading for academics and researchers in the field of asthma."-Respiratory Medicine
"This is still the only book on asthma that brings together recent information on basic mechanisms and covers in depth clinical aspects and therapy."
-Trends in Pharmacological Science
From The Critics
Reviewer: David I. Bernstein, MD(University of Cincinnati College of Medicine)Description: This authoritative book examines in great detail the characteristic components of asthma with special emphasis on the cells and mediators that contribute to airway inflammation.
Purpose: The purpose of the third edition is to provide an overview of mechanisms and therapy of asthma and to update scientists and clinicians on new concepts in the treatment of this disease. This book is comprehensive, well referenced, and authored by an outstanding list of experts.
Audience: It is written for the basic scientist or clinical researcher. The emphasis is clearly on mechanistic aspects of the disease and its treatment. For the most part there is a truly outstanding group of contributors who are recognized experts in their respective fields.
Features: Every important mechanistic aspect of asthma is described in great detail. The important role of allergens in asthma is emphasized as are new therapies such as the leukotriene inhibitors and methods of allergen avoidance. This book is designed for the advanced student of asthma and would not provide the integrated overview sought by students or medical residents. It does not adequately address the role of allergen immunotherapy in the treatment of atopic asthma, a widely practiced treatment modality outside the United Kingdom.
Assessment: This text is well referenced and provides many informative tables and illustrations which aid the reader in integrating emerging new concepts about the mechanisms of this disease. Chapters dealing with important treatment aspects such as allergen avoidance and environmental control, childhood asthma, and glucocorticoid and future therapies are practical and represent particularly useful information for the clinician.
David I. Bernstein
This authoritative book examines in great detail the characteristic components of asthma with special emphasis on the cells and mediators that contribute to airway inflammation. The purpose of the third edition is to provide an overview of mechanisms and therapy of asthma and to update scientists and clinicians on new concepts in the treatment of this disease. This book is comprehensive, well referenced, and authored by an outstanding list of experts. It is written for the basic scientist or clinical researcher. The emphasis is clearly on mechanistic aspects of the disease and its treatment. For the most part there is a truly outstanding group of contributors who are recognized experts in their respective fields. Every important mechanistic aspect of asthma is described in great detail. The important role of allergens in asthma is emphasized as are new therapies such as the leukotriene inhibitors and methods of allergen avoidance. This book is designed for the advanced student of asthma and would not provide the integrated overview sought by students or medical residents. It does not adequately address the role of allergen immunotherapy in the treatment of atopic asthma, a widely practiced treatment modality outside the United Kingdom. This text is well referenced and provides many informative tables and illustrations which aid the reader in integrating emerging new concepts about the mechanisms of this disease. Chapters dealing with important treatment aspects such as allergen avoidance and environmental control, childhood asthma, and glucocorticoid and future therapies are practical and represent particularly useful information for the clinician.Library Journal
Expensive, but the core resource in the field. It offers a comprehensive overview, incorporating current information related to asthma's pathobiology and clinical aspects. The 148 chapters range from the basic sciences to management of the disease in both adults and children. For medical libraries. Copyright 2000 Cahners Business Information.Booknews
Provides health professionals and scientists with a comprehensive overview of the entire field of asthma, incorporating current information related to its pathobiology and clinical aspects. The 148 chapters range from the basic science of pro-inflammatory processes to practical issues pertaining to day-to-day management of the disease in both adults and children. Sections cover epidemiology; structure, biology and pathology; inflammatory cells; inflammatory mediators; target cells; neural mechanisms; inducers and triggers; respiratory physiology; clinical assessment; and therapy and management. Annotation c. by Book News, Inc., Portland, Or.Booknews
Brings together recent information on basic mechanisms of asthma and also covers clinical aspects and therapy in depth. Coverage includes epidemiology, genetics, airway smooth muscle cells, lymphocytes, epithelial cells, adhesion molecules, prostaglandins and thromboxane, pathophysiology of asthma, occupational asthma, atmospheric pollutants, and pharmacoeconomics of asthma treatments. For basic researchers and clinicians. This third edition incorporates advances in the field since 1992 and contains new chapters. Annotation c. by Book News, Inc., Portland, Or.3 Stars from Doody
Product Details
Related Subjects
Meet the Author
Peter Barnes is Professor of Thoracic Medicine at the National Heart and Lung Institute, Head of Respiratory Medicine at Imperial College and Honorary Consultant Physician at Royal Brompton Hospital, London. He qualified at Cambridge and Oxford Universities was appointed to his present post in 1987. He has published over 1000 peer-review papers on asthma, COPD and related topics and has edited over 40 books. He is also amongst the top 50 most highly cited researchers in the world and has been the most highly cited clinical scientist in the UK and the most highly cited respiratory researcher in the world over the last 20 years. He was elected a Fellow of the Royal Society in 2007, the first respiratory researcher for over 150 years. He is currently a member of the Scientific Committee of the WHO/NIH global guidelines on asthma (GINA) and COPD (GOLD). He also serves on the Editorial Board of over 30 journals and is currently an Associate Editor of Chest and respiratory Editor of PLoS Medicine. He has given several prestigious lectures, including the Amberson Lecture at the American Thoracic Society and the Sadoul Lecture at the European Respiratory Society.
Neil Thomson is Professor of Respiratory Medicine at the University of Glasgow, Head of Respiratory Medicine within the Division of Immunology, Infection & Inflammation and Honorary Consultant at Gartnavel General Hospital, Glasgow. He graduated from the University of Glasgow and undertook postgraduate training in Glasgow, London and McMaster University, Canada. He is a former member of the Committee for Safety of Medicine and former Chair of the Scientific Committee of the British Lung Foundation. He has co-edited several textbooks on asthma and COPD and published over 150 peer-reviewed papers on asthma. His current research interests include corticosteroid insensitivity in smokers with asthma, biomarkers in asthma and COPD and assessment of novel treatments for asthma.
Table of Contents
M. Sears, Epidemiology.
B. Meijer, E. Bleecker, and D. Postma, Genetics of Asthma.
P. Jeffrey, Airway Pathology in Asthma.
N. Pride, Physiology.
L.J. Janssen, E.E. Daniel, and I.W. Rodger, Airway Smooth Muscle Cells.
F.L. Pearce, Mast Cells and Basophils.
C.M. Hawrylowicz and T.H. Lee, Monocytes, Macrophages and Dendritic Cells.
P. Venge, The Eosinophil.
G. Anderson, Lymphocytes.
J.L. Devalia, M.M. Abdelaziz, and R.J. Davies, Epithelial Cells.
Y.C. Liu, A.M. Khawaja, and D.F. Rogers, Pathophysiology of Airway Mucus Secretion in Asthma.
D.J. Godden, Tracheobronchial Circulation.
A. Wardlaw, Adhesion Molecules.
C. Persson, Microvascular-EpithelialExudation of Plasma.
P.M. OByrne, Prostaglandins and Thromboxane.
J. Drazen, Cysteinyl Leukotrienes.
D. Proud, Kinins.
K.F. Chung, Chemokines.
D.S. Robinson, Lymphokines.
F.K. Chung and P.J. Barnes, Other Mediators of Asthma.
P.J. Barnes, Nitric Oxide.
P.J. Barnes, Neural Control of Airway Function in Asthma.
N.C. Thomson, Humoral Control of Airway Tone.
P.J. Barnes, Nanc Nerves and Neuropeptides.
P.J. Barnes, Pathophysiology of Asthma.
R. Newton, P.J. Barnes, and L.M. Adcock, Transcription Factors.
T.R. Bai, C.R. Roberts, and P.D. Pare, Airway Remodeling.
D.W. Cockcroft, Allergens.
A.J. Newman-Taylor, Occupational Asthma.
W.W. Busse, E.C. Dick, R.F. Lemanske, Jr., and J.E. Gern, Infections.
S.D. Anderson, Asthma Provoked by Exercise.
R.A. Jorres and H. Magnussed, Atmospheric Pollutants.
P.J. Barnes and N.C. Thomson, Drug Induced Asthma.
A. Szezeklik, Aspirin-Induced Asthma.
A. Custovic and A. Woodcock, Allergen Avoidance.
I.P. Hall and A.E. Tattersfield, B-Agonists.
N.J. Gross, Anticholinergic Bronchodilators.
P.J. Barnes, Theophylline.
A.J. Chauhan, N.J. Withers, T.M. Krishna, and S.T. Holgate, Cromones.
P.J. Barnes, Glucocorticosteroids.
P.J. Barnes and K.F. Chung, Mediator Antagonists.
C.J. Corrigan, Immunomodulators.
P.J. Barnes, I.W. Rodger, and N.C. Thomson, Future Therapies for Asthma.
G.K. Crompton, Management of Severe Asthma.
A.J. Woolcock, Management of Asthma in Adults.
S. Pedersen, Asthma in Children.
S.D. Sullivan and K.B. Weiss, Pharmacoeconomics of Asthma Treatments.
M.R. Partridge, Education and Self Management.
Subject Index.