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Doody's Review ServiceReviewer: Beverly P. Nelson, MD (Northwestern University Feinberg School of Medicine)
Description: The sixth edition of this atlas covers techniques of collecting patient specimens and preparing well made smears suitable for interpretations. Illustrations are provided to aid in the interpretation of the morphologic findings encountered in specimens from peripheral blood, bone marrow, lymph node, and spleen. The prior edition was published in 2000.
Purpose: The atlas illustrates the morphologic findings that serve as the basis to direct further ancillary testing used to confirm diagnoses of many hematologic disorders. Thus the various cell types are placed in the context of molecular/genetic changes that define specific hematologic disorders.
Audience: This book is particularly useful for pathology students and residents as well as oncologists. However, any practitioner who evaluates blood or bone marrow smears will find it valuable.
Features: The atlas illustrates normal hematopoietic cells as well as abnormal cells that are encountered in disease states involving peripheral blood, bone marrow, lymph nodes, and spleen. Diagrams/depictions of pertinent genetic alterations are illustrated where it is appropriate. Tables are effectively used to provide a synopsis of findings useful to discriminate between different diagnostic entities. The section about blood parasites and organisms causing tropical diseases makes this atlas more complete. The only shortcoming is that English appears not to be the native language of the authors in at least one diagram (page 308; Scheme 5).
Assessment: This is an excellent reference. It is useful to learn morphology of normal peripheral blood and bone marrow cells and also to become familiar with abnormal cells that are present in the various hematologic diseases including leukemias, lymphomas, and some infectious diseases. The preceding edition was updated to include current WHO terminology for leukemia, lymphoma, and myelodysplastic syndromes.