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Doody's Review ServiceReviewer: Valerie L. Ng, PhD MD(Alameda County Medical Center/Highland Hospital)
Description: This is the second edition of a fairly comprehensive reference atlas of clinical hematology.
Purpose: The purpose is to present hematological disorders with an emphasis on pictures and visually attractive presentations. These are worthy objectives, as the discipline of clinical hematology lends itself especially well to visual displays. This book nicely meets the objectives.
Audience: Although the audience is not specified, the atlas would appeal to anyone interested in clinical hematology, from medical students to residents, with a special appeal for clinical hematology fellows, attendings or practitioners, and laboratory medicine residents, hematopathology fellows and attendings, hematology laboratory directors, and clinical laboratory scientist students or practitioners. The editor and authors are internationally recognized for their expertise.
Features: This is a gorgeous atlas. The first four chapters are devoted to hematological malignancies, the fifth to coagulation, the sixth to anemias, and the last to hematopoietic stem cells and cytokines. Each chapter nicely links clinical laboratory and pathology findings with clinical presentations, key physical findings, diagnostic algorithms, and treatment strategies. The pictures span quite a range of clinicopathologic correlations, and most are quite exemplary. The text tends to be sparse, with key information often presented in tables or in the legends accompanying the figures or tables. A few quibbles. Many of the peripheral blood smears are too pale and the staining color is off. Certain truly esoteric hematological disorders (e.g., Diamond-Blackfan syndrome, the congenital dyserythropoietic anemias, Cobalamin C/D/E deficiencies, neonatal hematological disorders) are not included, so this atlas is not truly comprehensive. The field is advancing so quickly that the hematopoietic stem cell chapter appears sparse. Notably, certain drugs arising from this research and growing in clinical usage (e.g., erythropoietin, G-CSF) are not even listed in the index. From a laboratory medicine perspective, I was left wanting better pictures (i.e., color reproductions) of peripheral blood smears and bone marrow specimens. However, the trade-off for me was the advantage of having pictures demonstrating key physical findings and information on clinical diagnosis and treatment. In this regard, there are other, more comprehensive pathology/hematopathology/hematology atlases to satisfy a need for more extensive treatment of hematopathological disorders (e.g., Collins and Swerdlow, Pediatric Hematopathology (Elsevier, 2001), Farhi et al., Pathology of Bone Marrow and Blood Cells (Lippincott Williams & Wilkins, 2004), Bain, Bone Marrow Pathology, 3rd edition (Blackwell Publishing, 2001), Rozenberg, Microscopic Haematology: A Practical Guide for the Laboratory, 2nd edition (informa Healthcare/Taylor & Francis, 2003), Kjeldsberg et al., Practical Diagnosis of Hematologic Disorders, 4th edition (American Society for Clinical Pathology Press, 2006), etc.). And, finally, regarding recoagulation - it is too bad videos could not be incorporated, as the Furie video on thrombus formation with color-tagged clotting cascade components would have been perfect. I like this book for everything except the laboratory medicine/pathology pictures because I'm fortunate to already have at hand multiple more extensive and comprehensive atlases for this area.
Assessment: This is a beautiful atlas, wonderful for teaching and reviewing all aspects of clinical hematology. It would be a great addition to the bookshelf to have handy prior to consulting on a case.