Atlas of PET/CT with SPECT / CT with DVD

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Overview

This state-of-the-art, lavishly illustrated atlas is your visual guide to fusion imaging of all parts of the body. It combines CT with molecular imaging modalities such as PET and SPECT, resulting in significantly enhanced resolution of tumors and other disease processes that give you a unique view into their diagnosis, localization, and spread. Edited by the pioneers of fusion imaging, this new resource will help you more accurately diagnose and effectively guide treatment of human malignancies, including head and neck, lung, colon, ovarian, breast, lymphoma, melanoma, and many others, as well as other diseases such as infections.

• Emerging techniques such as PET/CT and SPECT/CT offer better diagnostic accuracy.

• More than 1,000 full-color images help you solve your toughest diagnostic challenges.

• Hundreds of case studies of normal and abnormal findings provided by two leading academic centers in nuclear medicine let you compare your findings with theirs.

• Fusion imaging lets you provide the most appropriate treatment based on your findings.

• Summaries and Key Points boxes for each case assist you in locating key content more easily.

• The accompanying DVD-ROM, which contains many fully navigable PET/CT and SPECT/CT cases for viewing and analysis, with cross-modality image fusion offers exceptional visual guidance. This DVD-ROM uses RAPID Software provided by Hermes Medical Solutions, www.hermesmedical.com.

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Editorial Reviews

Doody's Review Service
Reviewer: Oussama Nachar, MD, PhD (Ochsner Clinic Foundation)
Description: This nuclear medicine atlas provides a complete overview of the diagnostic aspect of PET-CT and SPECT-CT in an organ site-oriented manner. The book is very well organized with abundant illustrations and teaching points. This is an excellent companion for nuclear medicine physicians and radiologists in practice as well as residents in-training in these fields.
Purpose: The authors succeed in their aim of delivering an anatomically based reference book that addresses the most important aspects of PET-CT and SPECT-CT.
Audience: The audience includes nuclear medicine professionals, radiologists, oncologists, and residents and fellows. This atlas is a valuable companion for new practitioners as well as experienced nuclear medicine physicians who interpret either PET-CT or SPECT-CT.
Features: This book covers the full range of FDG PET-CT by organ site. The authors clearly and succinctly present the most important teaching points. In particular, the discussions about the normal variants and the benign conditions are noteworthy and make a complicated subject easier for the reader to assimilate.
Assessment: Nuclear medicine books that cover the diagnostic aspects of PET-CT by organ site are rare. The format and the quality of the information presented by this atlas's panel of talented authors render a difficult subject easier to approach. This excellent atlas will be a great addition to any nuclear medicine physician's library and a precious asset to all the residents and fellows in the fields of nuclear medicine and radiology who are called to interpret PET-CT.
From the Publisher
This is a pictorial atlas aimed at practitioners in hybrid imaging or those interested in developing their skills in these growing techniques. The cases are comprehensive and well thought out. There is a logical progression from normal variants to benign conditions to malignancy. The layout is stylish and the text easy to assimilate. The accompanying DVD is a useful tool. Overall I liked the book and it sits well in our PET/CT Centre and Nuclear Medicine Department.

Sally Barrington, Guys and St Thomas’, SCOPE Magazine 2008

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Product Details

  • ISBN-13: 9781416033615
  • Publisher: Elsevier Health Sciences
  • Publication date: 11/16/2007
  • Pages: 304
  • Product dimensions: 8.60 (w) x 11.00 (h) x 0.80 (d)

Table of Contents

1. PREFACE

2. TECHNICAL CONSIDERATIONS FOR PET/CT AND SPECT/CT

3. PET/CT OF THE BRAIN

3.1 Normal pattern
3.2 Benign abnormalities
3.2.1 Congenital encephalomalacia
3.2.2 Post-surgical changes
3.2.3 Radiation necrosis
3.3 Tumors
3.3.1 Primary brain tumor
3.3.2 Metastases
3.3.3 Residual tumor & post-surgical changes
3.3.4 Recurrent tumor & radiation necrosis
3.3.5 Pituitary adenoma & stroke
3.4 Neurological disorders
3.4.1 Epilepsy – classic interictal pattern
3.4.2 Epilepsy – interictal pattern & cerebellar diaschisis
3.4.3 Epilepsy – interictal & decreased cerebellar uptake
3.4.4 Alzheimer’s disease – diffuse pattern
3.4.5 Alzheimer’s disease – frontal predominance

4. PET/CT OF THE HEAD & NECK

4.1 Normal pattern
4.2 Physiologic, Artifacts & Pitfalls
4.2.1 Artifact - miss-registration due to patient movement
4.2.2 Physiologic – muscles uptake in tongue
4.2.3 Physiologic – unilateral muscle uptake, mastication
4.2.4 Physiologic - bilateral muscle uptake, mastication
4.2.5 Physiologic – unilateral muscle uptake, neck
4.2.6 Physiologic – unilateral muscle uptake, torticollis & metal artifact
4.2.7 Pitfall - vocal cord paralysis, left
4.2.8 Pitfall - vocal cord paralysis, right & supraclavicular node
4.2.9 Benign - brown fat, neck
4.2.10 Benign - brown fat, neck & shoulders
4.2.11 Benign - post-treatment changes, skin & subcutaneous tissue
4.2.12 Benign - post-treatment changes, reconstituted lymphoid tissue & muscles
4.2.13 Benign - post-surgical changes & missing salivary gland
4.2.14 Benign - post-treatment changes & FDG-negative salivary gland
4.2.15 Pitfall - post-surgical changes, missing orbit & ethmoid air cells
4.3 Inflammation & Infection
4.3.1 Inflammation, tracheostomy
4.3.2 Infection, acne
4.3.3 Infection, maxillary sinusitis, partial involvement
4.3.4 Infection, maxillary sinusitis, involvement of whole sinus
4.3.5 Mucus cyst in maxillary sinus, FDG-negative
4.3.6 Inflammation, rheumatoid arthritis, atlanto-dental joint
4.4 Tumors
4.4.1 Scalp, melanoma
4.4.2 Scalp, melanoma
4.4.3 Scalp, FDG-negative
4.4.4 Auditory canal
4.4.5 Parotis & peri-parotid nodes
4.4.6 Parotis
4.4.7 Nasopharynx, response to treatment
4.4.8 Lip
4.4.9 Base of tongue
4.4.10 Tongue & level II nodes
4.4.11 Tonsil & level II nodes
4.4.12 Pharynx
4.4.13 Pharynx & cervical nodes
4.4.14 Larynx & tracheostomy
4.4.15 Larynx & tracheal cartilage destruction
4.4.16 Vocal cord
4.4.17 Cervical esophageal cancer
4.4.18 Neural sheath
4.4.19 Bone, vertebral metastasis
4.5 Lymph Nodes
4.5.1 Level I
4.5.2 Level I & II
4.5.3 Level II
4.5.4 Level II
4.5.5 Level II & III
4.5.6 Level IV
4.5.7 Level V
4.5.8 Level VI
4.6 Thyroid
4.6.1 Benign - Thyroiditis
4.6.2 Benign – Multinodular retrosternal goiter
4.6.3 Benign – Adenoma & distorted anatomy
4.6.4 Tumor - Primary thyroid cancer

5. PET/CT OF THE CHEST

5.1 Normal Pattern
5.2 Chest wall
5.2.1 Pitfall – Gynecomastia
5.2.2 Pitfall - Muscular uptake, asymmetric
5.2.3 Pitfall - Axillary post-injection uptake
5.2.4 Benign – Brown fat, shoulder & upper chest wall
5.2.5 Benign – Post-surgical changes
5.2.6 Tumor – Chest wall recurrence, breast cancer
5.3 Breast
5.7.1 Artifact – Saline implants, cold lesion
5.7.2 Pitfall - Seroma
5.7.3 Benign – Granuloma
5.7.4 Benign – Post-radiation changes
5.7.5 Tumor – Large primary breast cancer
5.7.6 Tumor - Primary breast cancer & axillary nodes
5.7.7 Tumor – Recurrent breast cancer & axillary nodes
5.4 Skeleton
5.4.1 Benign – Rib fractures, varying ages
5.4.2 Benign – Fracture, sternum
5.4.3 Benign – Osteophyte, thoracic vertebra
5.4.4 Benign – Post-radiation “cold” vertebrae
5.4.5 Tumor – Metastasis, rib
5.4.6 Tumor – Metastasis, sternum
5.4.7. Tumor – Metastases, thoracic vertebrae
5.5 Pleura
5.5.1 Benign – Inflammation, pleurodesis, localized pattern
5.5.2 Benign – Inflammation, pleurodesis, diffuse pattern
5.5.3 Tumor - Malignant pleural effusion
5.5.4 Tumor – Pleural thickening, mesothelioma
5.5.5 Tumor – Pleural nodule, malignant implant
5.5.6 Tumor – Pleural masses, mesothelioma
5.6 Lung
5.6.1 Pitfall – Miss-registration, related to respiration
5.6.2 Benign - Post-radiation changes
5.6.3 Benign - Pneumonia
5.6.4 Benign – Pulmonary sarcoidosis
5.6.5 Benign – FDG-negative small lung nodule
5.6.6 Benign – FDG-negative lung nodule & interval shrinkage
5.6.7 Benign – Single lung nodule, granuloma
5.6.8 Tumor – Single lesion, primary lung cancer
5.6.9 Tumor – Single cystic lesion, primary lung cancer
5.6.10 Tumor - Moderate FDG avidity, bronchiolo-alveolar lung cancer
5.6.11 Tumor – Pancoast, with chest involvement & lung metastasis
5.6.12 Tumor – Response to treatment, primary & hilar nodes
5.6.13 Tumor – Metachronous lung cancer
5.6.14 Tumor – Recurrent mesothelioma & post-surgical changes
5.6.15 Tumor – Multiple lesions, multifocal lung cancer
5.6.16 Tumor – Multiple lesions, lymphoma
5.6.17 Tumor – Multiple lesions, inhomogeneous pattern, lymphoma
5.6.18 Tumor – Multiple lesions, metastases
5.6.19 Tumor – Multiple lesions, FDG-negative metastases
5.6.20 Tumor – Multiple lesions, treated & new metastases
5.7 Thoracic Lymph Nodes
5.7.1 Supraclavicular
5.7.2 Retroclavicular & pectoralis
5.7.3 Axillary & pectoralis
5.7.4 Axillary
5.7.5 Internal mammary
5.7.6 Supradiaphragmatic
5.8 Mediastinal Lymph Nodes
5.8.1 Anterior mediastinal & paratracheal
5.8.2 Prevascular, normal size
5.8.3 Aorto-pulmonary window
5.8.4 Precarinal & subcarinal
5.8.5 Paraesophageal
5.8.6 Multiple: pretracheal,paratracheal, tracheo-bronchial & hilar
5.8.7 Response to treatment, Retrocaval-paratracheal & paraspinal
5.9 Mediastinum
5.9.1 Pitfall – Brown fat
5.9.2 Pitfall - Blood clot
5.9.3 Benign – Thymus
5.9.4 Tumor - Bulky disease, lymphoma
5.9.5 Tumor – Endotracheal lesion, recurrent lung cancer
5.10 Esophagus
5.10.1 Pitfall - Hiatal hernia
5.10.2 Pitfall - Gastric pull-up
5.10.3 Benign - Esophagitis, post-radiation
5.10.4 Tumor - Esophageal cancer, proximal
5.10.5 Tumor - Esopageal cancer, distal
5.10.6 Tumor - Response to treatment, distal
5.11 Cardio-vascular
5.11.1 Benign - Takayasu’s aortitis
5.11.2 Benign - Coronary calcifications & pericardial effusion
5.11.3 Assessment of myocardium - Scar
5.11.4 Assessment of myocardium - Viability & apical scar
5.11.5 Assessment of myocardium - Cardiomyopathy
5.11.6 Cardiac PET/CT – Normal myocardial perfusion & coronary anatomy
5.11.7 Cardiac PET/CT – Ischemia & coronary calcifications, narrowing

6. PET/CT OF THE ABDOMEN

6.1 Normal pattern
6.2 Abdominal wall
6.2.1 Pitfall – Colostomy
6.2.2 Pitfall – Pararenal brown fat
6.2.3 Pitfall – Anterior abdominal brown fat,
6.2.4 Pitfall – Paracolic brown fat
6.2.5 Benign - Surgical scar
6.2.6 Benign – Rib fracture
6.2.7 Tumor - Metastasis
6.3 Liver & spleen
6.3.1 Pitfall – Intracholdedocal stent
6.3.2 Pitfall – Lesions at liver/lung interface
6.3.3 Benign – Chronic cholecystitis
6.3.4 Tumor – Primary hepatocellular carcinoma
6.3.5 Tumor – Single liver metastasis at lower pole
6.3.6 Tumor – Multiple liver metastases
6.3.7 Tumor – Recurrent metastasis at site of surgery
6.3.8 Tumor – Single spleen metastasis
6.3.9 Tumor – Multiple lesions in spleen
6.3.10 Tumor – Spelnomegaly & diffuse involvement by lymphoma
6.4 Pancreas
6.4.1 Tumor – Cancer in head of pancreas
6.4.2 Tumor – Cancer in tail of pancreas
6.4.3 Tumor & inflammatory process – Multiple pancreatic lesions
6.5 Stomach
6.5.1 Physiologic gastric uptake
6.5.2 Tumor - Lymphoma in distal antrum
6.5.3 Tumor - Gastric cancer, diffuse involvement
6.5.4 Tumor – Large mass, GIST
6.5.5 Tumor – Recurrence in gastric stump
6.6 Bowel
6.6.1 Benign – Colon adenoma
6.6.2 Tumor – Primary colon cancer
6.6.3 Tumor – Metastasis in small intestine
6.7 Peritoneum
6.7.1 Benign - Granulomatotic nodule
6.7.2 Tumor - Single metastatic nodule
6.7.3 Tumor - Multiple metastatic nodules
6.7.4 Tumor – Diffuse pattern, peritoneal seeding
6.7.5 Tumor – Peritoneal masses, GIST
6.8 Kidney & Adrenals
6.8.1 Pitfall – Regional lymphadenopathy near renal pelvis
6.8.2 Pitfall – Single kidney
6.8.3 Pitfall – Ectopic kidney
6.8.4 Pitfall – Horseshoe kidney
6.8.5 Pitfall – Distorted renal pelvis
6.8.6 Tumor - Single renal metastasis
6.8.7 Tumor – Multiple renal lesions, lymphoma
6.8.9 Tumor – Single adrenal metastasis
6.8.10 Tumor - Bilateral adrenal involvement, lymphoma
6.9 Lymph Nodes
6.9.1 Gastro-hepatic ligament
6.9.2 Hepatic hilum
6.9.3 Splenic hilum
6.9.4 Mesenteric & retroperitoneal
6.9.5 Root of mesentery
6.9.6 Para-aortic
6.9.7 Aorto-caval
6.9.8 Iliac
6.10 Vascular
6.10.1 Pitfall - Aortic wall calcifications
6.10.2 Pitfall - Aortic aneurysm
6.10.3 Benign - Aortic graft infection & psoas muscle abscess
6.11 Bone (Lumbar spine)
6.11.1 Benign - Degenerative changes, vertebral body
6.11.2 Benign - Degenerative changes, articular facets
6.11.3 Benign - Degenerative changes, intervertebral disc
6.11.4 Tumor - Lytic FDG-avid metastasis
6.11.5 Tumor – Sclerotic FDG-negative metastases
6.11.6 Tumor – Bone & soft tissue metastasis

7 PET/CT OF THE PELVIS

7.1.1 Normal pattern - Male pelvis
7.1.2 Normal pattern - Female pelvis
7.2 Pelvic wall, Soft tissues & Peritoneum
7.2.1 Pitfall – Focal uptake, Colostomy
7.2.2 Pitfall – Focal uptake, Inguinal hernia
7.2.3 Pitfall – Focal uptake, Urinary catheter
7.2.4 Benign – Skin granuloma
7.2.5 Benign – Infection, pilonidal sinus
7.2.6 Benign – Infection, pelvic abscess
7.2.7 Tumor - Presacral recurrence, rectal cancer
7.2.8 Tumor – Metastasis, psoas muscle
7.2.9 Tumor – Metastases, focal peritoneal nodule
7.2.10 Tumor - Diffuse peritoneal involvement
7.3 Gastro-intestinal tract
7.3.1 Pitfall – Physiologic bocal uptake in bowel
7.3.2 Benign – Rectal polyp
7.3.3 Benign – Inflammatory bowel disease
7.3.4 Tumor – Primary rectal cancer
7.3.5 Tumor – Primary recto-sigmoid cancer & para-rectal nodes
7.3.6 Tumor – Response to treatment, Metastatic rectal cancer
7.3.7 Tumor - Recurrence, rectal cancer
7.3.8 Tumor – Recurrence, rectal cancer & iliac nodes
7.4 Urinary tract
7.4.1 Pitfall - Ectopic pelvic kidney
7.4.2 Pitfall - Renal transplant
7.4.3 Pitfall – Focal uptake in ureter
7.4.4 Pitfall – Focal uptake in obstructed ureter
7.4.5 Pitfall - Dilated prostatic urethra
7.4.6 Pitfall - Bladder diverticulum
7.4.7 Pitfall - Bladder herniation
7.4.8 Tumor – Carcinoma of ureter
7.4.9 Tumor- Carcinoma of urinary bladder
7.5 Ovary, Cervix, Uterus
7.5.1 Pitfall - Ovulating ovary
7.5.2 Pitfall – Menstruation
7.5.3 Tumor- Lymphoma in ovary
7.5.4 Tumor – Primary ovarian cancer
7.5.5 Tumor – Ovarian cancer, recurrence at site of previous surgery
7.5.6 Tumor – Primary cervical cancer
7.5.7 Tumor – Primary cervical cancer, inhomogeneous uptake pattern
7.5.8 Tumor – Primary cervical cancer & iliac nodes
7.5.9 Tumor – Recurrence, cervical cancer
7.6 Prostate, Testis
7.6.1 Benign - Prostatic hypertrophy
7.6.2 Benign – Infection, Orchi-epidydimitis
7.6.3 Tumor - Lymphoma in testis
7.7 Lymph Nodes
7.7.1 Common & external iliac lymph nodes
7.7.2 Internal iliac lymph nodes
7.7.3 Internal iliac lymph nodes, lower pelvis
7.7.4 Inguinal lymph nodes & cervical cancer
7.7.5 Inguinal lymph nodes & metastatic gluteal mass
7.8 Vascular
7.8.1 Pitfall – Non-infected aorto-bifemoral bypass
7.8.2 Benign - Infected vascular graft
7.9 Bone
7.9.1 Pitfall – Post-radiation “Cod” sacrum
7.9.2 Benign - Sacral fracture
7.9.3 Benign – Paget’s disease
7.9.4 Tumor – Metastasis in sacrum & epidural space
7.9.5 Tumor – Metastasis in ilium & soft tissue

8. PET/CT OF EXTREMITIES

8.1 Skin
8.1.1 Benign - Surgical scar
8.1.2 Benign - Infected surgical scar
8.1.3 Benign - Infected ulcers
8.1.4 Tumor – Nodules, malignant melanoma
8.2 Soft tissue
8.2.1 Benign - Abscess
8.2.2 Tumor - Subcutaneous nodule, lymphoma
8.2.3 Tumor - Subcutaneous nodule, melanoma
8.2.4 Tumor – Sarcoma & bone involvement
8.3 Joints
8.3.1 Artifact - Periprosthetic uptake, metal-induced & reactive process
8.3.2 Benign - Periarticular uptake, bursitis
8.3.3 Benign - Periarticular uptake, synovitis
8.3.4 Benign – Teno-synovitis & tendon tear
8.3.5 Benign - Periprosthetic uptake, low grade infection
8.4 Muscles
8.4.1 Physiologic – Tense muscles
8.4.2 Tumor – Metastasis, breast cancer
8.4.3 Tumor – Metastases, rhabdo-myosarcoma
8.5 Lymph Nodes
8.5.1 Epitrochlear
8.5.2 Popliteal
8.5.3 Popliteal, large node
8.6 Vascular
8.6.1 Pitfall – Vascular uptake peri-calcifications
8.6.2 Benign - Infected vascular graft
8.7 Bone & bone marrow
8.7.1 Benign - Osteomyelitis
8.7.2 Tumor – Metastasis in scapula
8.7.3 Tumor – Metastasis in humerus
8.7.4 Tumor – Metastasis in femur
8.7.5 Tumor - Bone & soft tissue involvement, lymphoma
8.7.6 Tumor - Bone marrow involvement, multiple myeloma
8.7.7 Tumor - Bone marrow & soft tissue involvement, lymphoma
8.7.8 Tumor - Bone marrow & soft tissue involvement, lymphoma

9. SPECT/CT

9.1 Indium111-Pentetreotide SPECT/CT
9.1.1 Physiologic - Bowel & kidney uptake
9.1.2 Pitfall - Uptake in gallbladder
9.1.3 Tumor – Residual carcinoid
9.1.4 Tumor – Metastatic carcinoid
9.1.5 Tumor – Disseminated carcinoid
9.1.6 Tumor – Vertebral metastasis of neuroendocrine tumor
9.2 Iodine131 SPECT/CT
9.2.1 Physiologic – Remnant thyroid
9.2.2 Physiologic – Bowel uptake
9.2.3 Pitfall – Thymic uptake
9.2.4 Pitfall – Dental & uterine inflammatory process
9.2.5 Pitfall – Uptake in ectopic stomach
9.2.6 Tumor – Mediastinal nodal metastasis, thyroid cancer
9.2.7 Tumor – Cervical & supraclavicular nodal metastases, thyroid cancer
9.2.8 Tumor – Lung metastasis, Thyroid cancer
9.2.9 Tumor – Bone metastasis, Thyroid cancer
9.2.10 Tumor – Bone metastases, Thyroid cancer
9.3 Iodine123-MIBG SPECT/CT
9.3.1 Physiologic - Cardiac uptake
9.3.2 Physiologic – Inhomogeneous cardiac uptake & pheochromocytoma
9.3.3 Physiologic – Renal uptake
9.3.4 Physiologic – Adrenal uptake
9.3.5 Tumor – Bilateral pheochromocytoma
9.3.6 Tumor – Neuroblastoma & bone marrow involvement
9.4 Gallium67 SPECT/CT
9.4.1 Pitfall – Thymic uptake
9.4.2 Benign – Infection, osteomyelitis
9.4.3 Benign – Infection, bone & soft tissue; Bowel uptake
9.4.4 Benign – Infection, paravertebral abscess
9.4.5 Benign – Infection, liver abscess
9.4.6 Tumor – Lymphoma involving the head and neck & mediastinum
9.4.7 Tumor – Lymphoma in pelvic mass
9.4.8 Tumor – Lymphoma in muscle & Pitfalls: rib fracture & lung infiltrate
9.5 In111-capromab pendetide (Prostascint®) SPECT/CT
9.5.1 Normal study
9.5.2 Tumor – Abdominal lymphadenopathy, prostate cancer
9.6. Tc99m-MIBI SPECT/CT (Parathyroid Imaging)
9.6.1 Pitfall – Asymmetric salivary gland uptake & parathyroid adenoma
9.6.2 Tumor - Parathyroid adenoma in right lower neck
9.6.3 Tumor – Parathyroid adenoma in left lower neck
9.6.4 Tumor – Ectopic parathyroid adenoma
9.7. Tc99m-MDP SPECT/CT
9.7.1 Pitfall – Uptake related to renal calculus
9.7.2 Benign - Facet joint disease
9.7.3 Benign – Osteoarthritis in hip
9.7.4 Benign - Fibrous dysplasia
9.7.5 Benign - Myositis ossificans
9.7.6 Benign - Hematoma at injection site
9.8. In111 labeled Leucocytes SPECT/CT
9.8.1 Diabetic foot - Osteomyelitis & soft tissue
9.8.2 Diabetic foot - Soft tissue involvement
9.8.3 Diabetic foot - Soft tissue involvement
9.8.4 Bacteremia - Infected aortic plaque
9.9 Tc99m-MIBI SPECT/CT (Cardiac)
9.9.1 SPECT, myocardial perfusion/CT, attenuation correction - Normal study
9.9.2 SPECT, myocardial perfusion/CT, attenuation correction - Breast artifact
9.9.3 SPECT, myocardial perfusion/CT, attenuation correction - Diaphragm artifact
9.9.4 SPECT, myocardial perfusion/CT, attenuation correction - Scar & ischemia
9.9.5 SPECT/CT – Normal perfusion & coronary anatomy
9.9.6 SPECT/CT – Myocardial ischemia & coronary lesions

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