Atomic Force Microscopy in Cell Biology

Overview

This is the first book to cover the history, structure, and application of atomic force microscopy in cell biology. Presented in the clear, well-illustrated style of the Methods in Cell Biology series, it introduces the AFM to its readers and enables them to tap the power and scope of this technology to further their own research. A practical laboratory guide for use of the atomic force and photonic force microscopes, it provides updated technology and methods in force spectroscopy. It is also a comprehensive and...

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Overview

This is the first book to cover the history, structure, and application of atomic force microscopy in cell biology. Presented in the clear, well-illustrated style of the Methods in Cell Biology series, it introduces the AFM to its readers and enables them to tap the power and scope of this technology to further their own research. A practical laboratory guide for use of the atomic force and photonic force microscopes, it provides updated technology and methods in force spectroscopy. It is also a comprehensive and easy-to-follow practical laboratory guide for the use of the AFM and PFM in biological research.

Audience: Cell and developmental biologists, biotechnologists, physicologists, pharmocologists, biochemists, and students and researchers of molecular and cellular medicine.

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Editorial Reviews

From The Critics
Prepared under the auspices of the American Society for Cell Biology, this text encompasses the emergence in the past decade and applications of the atomic force microscope (AFM) in cell biology research. Jena (physiology and pharmacology, Wayne State U. School of Medicine, Detroit) and Hörber (European Molecular Biology Laboratory, Heidelberg) introduce 17 chapters contributed by international experts in the field to provide working knowledge of AFM developments, techniques, imaging limitations, study results, and potential in nanotechnology in combination with other new tools. Applications include study of the properties of living cells and single DNA molecules. A section of color plates concludes the volume. Annotation c. Book News, Inc., Portland, OR
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Product Details

  • ISBN-13: 9780123838513
  • Publisher: Elsevier Science
  • Publication date: 5/20/2002
  • Series: Methods in Cell Biology Series
  • Pages: 415
  • Product dimensions: 7.04 (w) x 9.76 (h) x 0.69 (d)

Table of Contents

Preface, Bhanu P. Jena & Heinrich Horber.
Local Probe Techniques, J.K. Heinrich Hörber.
AFM in the Study of Membrane Fusion and Exocytosis, Bhanu P. Jena, Sang-Joon Cho.
AFM Imaging of Cells and Membranes, Christian Le Grimellec, Eric Lesniewska, Pierre Milhiet, Marie-Cécile Giocondi.
Measuring the Elastic Properties of Living Cells by AFM, Manfred Radmacher.
Cell Adhesion Measured by Force Spectroscopy on Living Cells, Martin Benoit.
Molecular Recognition Studies Using AFM, Peter Hinterdorfer.
The Biophysics of Sensory Cells of the Inner Ear examined by AFM and Patch Clamp, Matthias G. Langer, Assen Koitschev.
Biotechnological Applications of Atomic Force Microscopy, Mike Horton, Guillaume Charras, Petri Lehenkari.
Cellular Membranes Studied by Photonic Force Microscopy, Arnd Pralle, Ernst-Ludwig Florin.
Methods for Biological Probe Microscopy in Aqueous Fluids, Helen G. Hansma, Johannes H. Kindt, John C. Sitko, Emin Oroudjev, Mario B. Viani, Nathan Becker, Lia I. Pietrasanta.
Supported Lipid Bilayers as Effective Substrates for Atomic Force Microscopy, Zhifeng Shao, Daniel M. Czajkowsky.
Cryo Atomic Force Microscopy, Zhifeng Shao, Sitong Sheng.
Conformations, Flexibility and Interactions Observed on Individual Membrane Proteins by Atomic Force Microscopy, Daniel J. Müller, Andreas Engel.
Single Molecule Force Measurements, Vincent T. Moy, Aileen Chen.
Forced Unfolding of Single Proteins, Pierre-Francois Lenne, S.M. Altmann.
Developments in Dynamic Force Microscopy and Spectroscopy, Mervyn Miles, A.D.L. Humphris.
SFM Studies on the Structure and Dynamics of Single DNA Molecules, Bruno Samorì, Giampaolo Zuccheri.

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