Description: This is an acceptable introduction to the basic science and clinical utilization of atypical antipsychotic agents. Its concise, well-organized chapters present an up-to-date review of current knowledge on relevant issues in this area. The editors and contributors have the requisite backgrounds to write authoritatively on this subject.
Purpose: This publication arrives at an opportune time to assess the progress of psychopharmacotherapy of psychotic and other disorders since the reintroduction of clozapine. Overall, the book generally provides a good discussion of the development and use of atypical antipsychotics.
Features: Written with the nonresearcher in mind, the book will be a helpful resource for medical students, residents, and clinical practitioners working with these agents.
Assessment: The book features discussions of basic pharmacology, including excellent reviews on mechanism of action, neurophysiological effects, and the role of animal models in the development of antipsychotics. Critical issues regarding the clinical efficacy of these agents for various disorders, as well as their safety and tolerability, are also addressed. While the book is generally clear and informative, some of the chapters attempt to cover too much material in an abbreviated form (e.g., chapters 9 and 12). The few illustrations and general layout are serviceable, but not exceptional.