Autism: Oxidative Stress, Inflammation, and Immune Abnormalities

by Abha Chauhan, Ved Chauhan, Ted Brown

Overview

In 2007, the Centers for Disease Control and Prevention issued an autism alarm, estimating that one in 150 children may be affected by autism spectrum disorder. Autism has been treated mainly with technical approaches: principally applied behavior analysis and psychopharmacology. The findings in this book implicate oxidative stress as a common feat

Product Details

ISBN-13:	9781040209233
Publisher:	CRC Press
Publication date:	10/26/2009
Sold by:	Barnes & Noble
Format:	eBook
Pages:	452
File size:	5 MB

About the Author

Ved Chauhan, Abha Chauhan, Ted Brown

Table of Contents

Type, Topography, and Sequelae of Neuropathological Changes Shaping Clinical Phenotype of Autism. Evidence for Oxidative Damage in the Autistic Brain. Oxidative Stress and Neurotrophin Signaling in Autism. Genetics of Autism. Phenotypic Expression of Autism, Maternal Depression, and the Monoamine Oxidase-A Gene. Paraoxonase 1 Status, Environmental Exposures, and Oxidative Stress in Autism Spectrum Disorders. The RedoxMethylation Hypothesis of Autism: A Molecular Mechanism for Heavy Metal-Induced Neurotoxicity. Autism and Oxidative Stress: Evidence from an Animal Model. Neurotoxic Brainstem Impairment as Proposed Threshold Event in Autistic Regression. Abnormalities in Membrane Lipids, Membrane-Associated Proteins, and Signal Transduction in Autism. Mitochondrial Component of Calcium Signaling Abnormality in Autism. Inflammation and Neuroimmunity in the Pathogenesis of Autism: Neural and Immune Network Interactions. Possible Impact of Innate Immunity on Autism. Autism, Gastrointestinal Disturbance, and Immune Dysfunction: What Is the Link. Possible Mechanism Involving Intestinal Oxytocin, Oxidative Stress, and Signaling Pathways in a Subset of Autism with Gut Symptoms. Cytokine Polymorphisms in Autism: Their Role in Immune Alterations. Autism, Teratogenic Alleles, HLA-DR4, and Immune Function. Autism: The Centrality of Active Pathophysiology and the Shift from Static to Chronic Dynamic Encephalopathy. A Reevaluation of the State of Autism Treatment: The Need for a Biopsychosocial Perspective.