The Bacteria: Their Origin, Structure, Function and Antibiosis / Edition 1

The Bacteria: Their Origin, Structure, Function and Antibiosis / Edition 1

by Arthur L. Koch
     
 

ISBN-10: 1402032056

ISBN-13: 9781402032059

Pub. Date: 06/15/2006

Publisher: Springer Netherlands

The book's purpose is to explain from the development of life on earth to the evolution of diversity. It is this diversity that led, almost automatically to the development of pathogens and predators. The relationship of pathogens and host lead to the development of antibiotics and resistance mechanism. Man has extended this process and we now have a situation in

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Overview

The book's purpose is to explain from the development of life on earth to the evolution of diversity. It is this diversity that led, almost automatically to the development of pathogens and predators. The relationship of pathogens and host lead to the development of antibiotics and resistance mechanism. Man has extended this process and we now have a situation in which new antibiotics only are effective for a short time. If we are to create long term antibiotics we must design them with this history in mind. Understanding antibiotic chemotherapy at the ecological level is necessary for more permanent advances in development and in the usage of antibiotic agents both old, new, and in the future. This book is indented for students at various levels that will be the microbiology researchers in the time to come. Also microbiology professors, particularly those teaching medical microbiology as well as physicians administering antibiotics daily and researchers in the pharmaceutical industry may find this book useful.

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Product Details

ISBN-13:
9781402032059
Publisher:
Springer Netherlands
Publication date:
06/15/2006
Edition description:
2006
Pages:
224
Product dimensions:
9.21(w) x 6.14(h) x 0.63(d)

Table of Contents

1The origin of life based on physical principles3
2Preamble to life9
3The first cell15
4Development of cell physiology and diversity21
5Covalent bonds and tensile strength of materials39
6Structure of the fabric that covers a bacterium49
7The covalently linked sacculus : the nona-muropeptide model61
8The structure of the tessera; the unit structure of murein wall71
9Extrusion and incorporation into the wall77
10The role of poles in the growth strategy of bacteria81
11Sidewalls of gram-negative rod-shaped bacteria91
12Growth strategies for gram-positive cells99
13Wall growth strategies for gram-negative cells109
14Commas, vibrios, spirilla, and helicobacters; tapered and branched bacteria119
15Spirochetes and spiroplasma and the special strategies for CWD (cell wall deficient) cells137
16Coccal versus rod-shaped cells, and the first bacterium147
17Diseases : old and new161
18Lysozymes as alternatives to [beta]-lactams antibiotics acting on the bacterial wall181
19Development of wall antibiotics and bacterial counter-measures185
20Antibiotics and resistance, with an emphasis on aminoglycosides201
21Future chemotherapy aimed at the bacterial murein209

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