The Bacteria: Their Origin, Structure, Function and Antibiosis / Edition 1

The Bacteria: Their Origin, Structure, Function and Antibiosis / Edition 1

by Arthur L. Koch
     
 

ISBN-10: 1402032056

ISBN-13: 9781402032059

Pub. Date: 04/24/2006

Publisher: Springer Netherlands

The book's purpose is to explain from the development of life on earth to the evolution of diversity. It is this diversity that led, almost automatically to the development of pathogens and predators. The relationship of pathogens and host lead to the development of antibiotics and resistance mechanism. Man has extended this process and we now have a situation in

Overview

The book's purpose is to explain from the development of life on earth to the evolution of diversity. It is this diversity that led, almost automatically to the development of pathogens and predators. The relationship of pathogens and host lead to the development of antibiotics and resistance mechanism. Man has extended this process and we now have a situation in which new antibiotics only are effective for a short time. If we are to create long term antibiotics we must design them with this history in mind. Understanding antibiotic chemotherapy at the ecological level is necessary for more permanent advances in development and in the usage of antibiotic agents both old, new, and in the future. This book is indented for students at various levels that will be the microbiology researchers in the time to come. Also microbiology professors, particularly those teaching medical microbiology as well as physicians administering antibiotics daily and researchers in the pharmaceutical industry may find this book useful.

Product Details

ISBN-13:
9781402032059
Publisher:
Springer Netherlands
Publication date:
04/24/2006
Edition description:
2006
Pages:
224
Product dimensions:
6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

Preface     vii
Legend to the Frontispiece     ix
Origin of Bacteria
The Origin of Life Based on Physical Principles     3
Preamble to Life     9
The First Cell     15
Development of Cell Physiology and Diversity     21
Wall Structure
Covalent Bonds and Tensile Strength of Materials     39
Structure of the Fabric that Covers a Bacterium     49
The Covalently Linked Sacculus: the Nona-Muropeptide Model     61
The Structure of the Tessera; the Unit Structure of Murein Wall     71
Extrusion and Incorporation into Wall     77
The Role of Poles in the Growth Strategy of Bacteria     81
Bacterial Morphologies
Sidewalls of Gram-Negative Rod-Shaped Bacteria     91
Growth Strategies for Gram-Positive Cells     99
Wall Growth Strategies for Gram-Negative Cells     109
Commas, Vibrios, Spirilla, and Helicobacters; Tapered and Branched Bacteria     119
Spirochetes and Spiroplasma and the Special Strategies for CWD (Cell Wall Deficient) Cells     137
Coccal Versus Rod-Shaped Cells, and the First Bacterium     147
Diseases: Old and New     161
Antibiosis
Lysozymes as Alternatives to [beta]-lactams Antibiotics Acting on the Bacterial Wall     181
Development of Wall Antibiotics and Bacterial Counter-Measures     185
Antibiotics and Resistance, with an Emphasis on Aminoglycosides     201
Future Chemotherapy Aimed at the Bacterial Murein     209
References     217

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