The Bacterial Chromosome

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An examination of the mechanisms governing genetic inheritance.
• Provides a link between classical experiments in chromosome physiology and new developments in genetic research.
• Covers the fundamental systems required for all bacterial cells to replicate chromosomes and organize genetic information.
• Presents complex biochemical reactions, including DNA replication, genetic recombination, and RNA transcription, from both genetic and physical perspectives.
• Incorporates the implications of the DNA sequence database with information on horizontal gene transfer and the impact of phage genes on bacterial genomes.
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Product Details

  • ISBN-13: 9781555812324
  • Publisher: ASM Press
  • Publication date: 10/28/2004
  • Pages: 559
  • Product dimensions: 8.46 (w) x 11.20 (h) x 1.23 (d)

Table of Contents

Table of Contents

Section I. Genetic and Physical Structure

1. Overview: Where's the Beef? Looking for Information About Bacterial Chromosomes, John R. Roth
2. The Dynamic Bacterial Genome, Jeffrey G. Lawrence
3. Bacteriophages and the Bacterial Genome, Sherwood Casjens and Roger W. Hendrix
4. Global Approaches to the Bacterial Cell as an Integrated System, Michael T. Laub, Lucy Shapiro, and Harley H. McAdams
5. Major Nucleoid Proteins in the Structure and Function of the Escherichia coli Chromosome, Reid C. Johnson, Lianna M. Johnson, John W. Schmidt, and Jeffrey F. Gardner
6. Domain Behavior and Supercoil Dynamics in Bacterial Chromosomes, N. Patrick Higgins, Shuang Deng, Zhenhua Pang, Richard A. Stein, Keith Champion, and Dipankar Manna
7. Stationary-Phase Chromosomes, Abraham Minsky and Roberto Kolter
Section II. Replication Machines

8. Replication Hits 50, Kenneth J. Marians
9. Initiation of Chromosomal Replication, Johanna Eltz and Elliott Crooke
10. DNA Elongation, Manju M. Hingorani and Mike O'Donnell
11. SeqA Protein Binding and the Escherichia coli Replication Fork, Therese Brendler and Stuart Austin
12. Reinitiation of DNA Replication, Kenneth N. Kreuzer and Benedicte Michel
13. The Terminus Region of the Escherichia coli Chromosome, or All's Well That Ends Well, Jean-Michel Louarn, Peter Kuempel, and Francois Cornet
Section III. Transcription Machines

14. Overview of Transcription, Jeffrey Roberts
15. The Structure of Bacterial RNA Polymerase, Kati Geszvain and Robert Landick
16. How Transcription Initiation Can Be Regulated in Bacteria, Simon L. Dove and Ann Hochschild
17. Control of Transcription Termination and Antitermination, Irina Artsimovitch
18. mRNA Decay and Processing, Sidney R. Kushner
Section IV. Homologous Recombination-Repair Machines

19. Overview of Homologous Recombination and Repair Machines, Andrei Kuzminov and Franklin W. Stahl
20. The RecA Protein, Michael M. Cox
21. Homologous Recombination by the RecBCD and RecF Pathways, Maria Spies and Stephen C. Kowalczykowski
22. Recombination Machinery: Holliday Junction-Resolving Enzymes, Malcolm F. White
23. Dr. Jekyll and Mr. Hyde: How the MutSLH Repair System Kills the Cell, M. G. Marinus
24. Excision Repair and Bypass, Bernard S. Strauss
25. Misalignment-Mediated Mutations and Genetic Rearrangements at Repetitive DNA Sequences, Susan T. Lovett
Section V. Nonhomologous Recombination

26. DNA Transposons: Different Proteins and Mechanisms but Similar Rearrangements, Keith M. Derbyshire and Nigel D. F. Grindley
27. Potential Mechanisms for Linking Phage Mu Transposition with Cell Physiology, Stella H. North and Hiroshi Nakai
28. Chromosome Dimer Resolution, Francois-Xavier Barre and David J. Sherratt
29. Replication of Linear Bacterial Chromosomes: No Longer Going Around in Circles, George Chaconas and Carton W. Chen

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