Bacterial Pathogenesis: A Molecular Approach / Edition 1

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Overview

Bacterial Pathogenesis: A Molecular Approach is the first text designed to provide a comprehensive introduction to this dynamic field for both students and researchers. The application of molecular techniques to the study of bacterium-host interaction has made possible great progress in fundamental understanding of the molecular basis of infectious diseases. In the text the authors integrate material from pathogenic microbiology, molecular biology, immunology, and human physiology to provide a complete but accessible overview of the field.

The book contains both black-and-white and color illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Cynthia V. Sommer, PhD (University of Wisconsin-Milwaukee)
Description: This textbook provides an understanding of the molecular mechanism involved in bacterial-host interactions that can produce infectious disease. Introductory chapters on host-parasite relationships are followed by discussions of well studied microorganisms that provide models of infectious disease.
Purpose: The purpose is to present recent advances on the role of bacteria in causing disease at the molecular level. The book integrates the genetics, biochemistry, cell biology, and immunology of bacterial pathogenesis. The authors meet their objective by providing a current textbook on molecular models of infectious diseases.
Audience: This textbook is written for advanced undergraduate, graduate, and medical students interested in infectious disease. The book will be a useful resource for microbiologists and scientists from various disciplines. The clear writing style and didactic approach should meet the needs of the intended audience. The authors and the list of reviewers insure the accuracy and quality of the book.
Features: Each chapter includes an introductory outline, summary, selected readings, and questions that stimulate critical thinking. The adequate number of illustrations are clear and support the text. The boxed highlights, the organization and content of the text should stimulate the interest of the reader. The appendixes that include bacterial structure, detection methods, answers to chapter questions, and a glossary provide the tools and information for readers with various levels of knowledge.
Assessment: This is a thoughtful and well-written textbook for students and professionals interested in infectious disease. The book supports and strengthens the shift in thinking in the current scientific literature about infectious diseases. This textbook fills a need for a current, concise molecular orientation to microbial pathogenesis .
From The Critics
Reviewer: Cynthia V. Sommer, PhD (University of Wisconsin-Milwaukee)
Description: This textbook provides an understanding of the molecular mechanism involved in bacterial-host interactions that can produce infectious disease. Introductory chapters on host-parasite relationships are followed by discussions of well studied microorganisms that provide models of infectious disease.
Purpose: The purpose is to present recent advances on the role of bacteria in causing disease at the molecular level. The book integrates the genetics, biochemistry, cell biology, and immunology of bacterial pathogenesis. The authors meet their objective by providing a current textbook on molecular models of infectious diseases.
Audience: This textbook is written for advanced undergraduate, graduate, and medical students interested in infectious disease. The book will be a useful resource for microbiologists and scientists from various disciplines. The clear writing style and didactic approach should meet the needs of the intended audience. The authors and the list of reviewers insure the accuracy and quality of the book.
Features: Each chapter includes an introductory outline, summary, selected readings, and questions that stimulate critical thinking. The adequate number of illustrations are clear and support the text. The boxed highlights, the organization and content of the text should stimulate the interest of the reader. The appendixes that include bacterial structure, detection methods, answers to chapter questions, and a glossary provide the tools and information for readers with various levels of knowledge.
Assessment: This is a thoughtful and well-written textbook for students and professionals interested in infectious disease. The book supports and strengthens the shift in thinking in the current scientific literature about infectious diseases. This textbook fills a need for a current, concise molecular orientation to microbial pathogenesis .
Cynthia V. Sommer
This textbook provides an understanding of the molecular mechanism involved in bacterial-host interactions that can produce infectious disease. Introductory chapters on host-parasite relationships are followed by discussions of well studied microorganisms that provide models of infectious disease. The purpose is to present recent advances on the role of bacteria in causing disease at the molecular level. The book integrates the genetics, biochemistry, cell biology, and immunology of bacterial pathogenesis. The authors meet their objective by providing a current textbook on molecular models of infectious diseases. This textbook is written for advanced undergraduate, graduate, and medical students interested in infectious disease. The book will be a useful resource for microbiologists and scientists from various disciplines. The clear writing style and didactic approach should meet the needs of the intended audience. The authors and the list of reviewers insure the accuracy and quality of the book. Each chapter includes an introductory outline, summary, selected readings, and questions that stimulate critical thinking. The adequate number of illustrations are clear and support the text. The boxed highlights, the organization and content of the text should stimulate the interest of the reader. The appendixes that include bacterial structure, detection methods, answers to chapter questions, and a glossary provide the tools and information for readers with various levels of knowledge. This is a thoughtful and well-written textbook for students and professionals interested in infectious disease. The book supports and strengthens the shift in thinking in the current scientific literature aboutinfectious diseases. This textbook fills a need for a current, concise molecular orientation to microbial pathogenesis .
Booknews
A comprehensive introduction to the study of bacterium-host interaction, and to progress and challenges in the understanding of the molecular basis of infectious diseases. Integrates material from pathogenic microbiology, molecular biology, immunology, and human physiology. Annotation c. Book News, Inc., Portland, OR booknews.com

3 Stars from Doody
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Product Details

  • ISBN-13: 9781555810702
  • Publisher: ASM Press
  • Publication date: 6/28/1994
  • Edition description: Older Edition
  • Edition number: 1
  • Pages: 418
  • Product dimensions: 8.54 (w) x 10.93 (h) x 0.85 (d)

Table of Contents

Preface
Foreword
Pt. I Basic Principles 1
Ch. 1 The Uneasy Truce: Never Underestimate the Power of Bacteria 3
Ch. 2 Approaching and Studying Bacterial Diseases 19
Ch. 3 Molecular Approaches to the Diagnosis and Characterization of Bacterial Infections 34
Ch. 4 The First Line of Defense against Infection: Prevention and the Phagocytic Cell Response 53
Ch. 5 The First Line of Defense, Continued: Complement, Chemokines, and Cytokines 69
Ch. 6 The Second Line of Defense: Antibodies and Cytotoxic T Cells 84
Ch. 7 Vaccination - an Underappreciated Component of the Modern Medical Armamentarium 101
Ch. 8 Bacterial Strategies for Evading or Surviving the Defense Systems of the Human Body 115
Ch. 9 Bacterial Exotoxins: Important but Still a Mystery 131
Ch. 10 Antimicrobial Compounds 150
Ch. 11 How Bacteria Become Resistant to Antibiotics 168
Pt. II Specific Bacterial Pathogens 185
Ch. 12 The Spirochetes: Borrelia burgdorferi and Treponema pallidum 187
Ch. 13 Yersinia pestis, the Cause of Plague, and Its Relatives 202
Ch. 14 Staphylococcus Species 216
Ch. 15 Group A and Group B Streptococci and Enterococci 232
Ch. 16 Pseudomonas aeruginosa and Related Species, a Lesson in Versatility 247
Ch. 17 Bordetella pertussis 263
Ch. 18 Streptococcus pneumoniae 276
Ch. 19 Tuberculosis 291
Ch. 20 Legionella pneumophila and Legionnaires' Disease 311
Ch. 21 Mycoplasma pneumoniae and Chlamydia pneumoniae 322
Ch. 22 Bacillus anthracis, the Cause of Anthrax 332
Ch. 23 Helicobacter pylori, a Resourceful Gastric Pathogen 339
Ch. 24 Clostridium difficile and Pseudomembranous Colitis 352
Ch. 25 Vibrio cholerae, the Cause of Cholera 363
Ch. 26 Salmonella Species 381
Ch. 27 Listeria monocytogenes, a Doubly Motile Pathogen 398
Ch. 28 Diarrheagenic Escherichia coli Strains 407
Ch. 29 Escherichia coli Extraintestinal Infections 422
Ch. 30 Neisseria Species 437
Ch. 31 Chlamydia trachomatis 452
App. 1 Overview of Bacterial Secretion Systems, Bacterial Adhesins and Their Mechanisms of Assembly, and Major Bacterial Toxins 461
App. 2: Answers to End-of-Chapter Questions 467
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