Basic Immunology: Functions and Disorders of the Immune System / Edition 2

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The 2nd edition of this popular text emphasizes the fundamental concepts and principles of human immunology that students need to know, without overwhelming them with extraneous material. It leads the reader to a firm understanding of basic principles, using full-color illustrations; short, easy-to-read chapters; color tables that summarize key information clinical cases; and much more—all in a conveniently sized volume that's easy to carry. The New Edition has been thoroughly updated to reflect the many advances that are expanding our understanding of the field.

• Presents all of the most important principles that govern the function of the immune system.

• Extrapolates key concepts from the vast amount of experimental data that has emerged.

• Focuses on cellular interactions in immune responses rather than describing in detail many of the underlying biochemical and molecular mechanisms.

• Emphasizes immune responses in human rather than experimental animals, drawing upon parallels with experimental situations only when necessary.

• Uses clear, crisp illustrations, diagrams, figures, charts and tables to highlight important principles.

• Illustrates how the principles of immunology may be applied to common human diseases through clinical cases in the Appendix.

• Features an easy-to-read layout; summarizes chapter content in bulleted lists accompanied by review questions; and offers a list of selected readings.

• all of the scientific advances that are expanding the knowledge base in this rapidly evolving field.

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Editorial Reviews

From The Critics
Reviewer:Marion C. Cohen, PhD(University of Medicine and Dentistry of New Jersey-NJMS)
Description:This compact book covers most of the major topics taught in basic immunology courses for medical and dental students. The material is presented in a very concise manner so that the level of detail is limited and some topics receive little attention. The most recent edition was published in 2006.
Purpose:The goal is to present a picture of how the immune system works in a way that allows students to learn basic principles without becoming bogged down in details that are more appropriately covered in advanced courses. Thus the book is limited to what the authors consider the key concepts of the field. Given the increase in information about the immune system, setting limits may be a good thing.
Audience:Medical students studying immunology during their preclinical years are the primary audience, but dental students could also use it.
Features:In addition to trying to cover the major topics that are taught in most medical immunology courses, this book focuses on human immune responses against infectious microbes. Factual details purposely have been limited. Although there are a few clinical cases presented in the appendix, immunologic diseases are presented in the chapters only to emphasize their relation to normal immune responses. Unfortunately, some topics are not covered. For example, there is little about the mucosal immune system, which is different from the peripheral immune system. The figures are presented well, but in some cases they are too complicated and condensed. (They are also available for use by faculty intheir presentations through Elsevier's Student Consult system.) There is also an extensive glossary and a list of the principal features of selected CD markers. At the end of each chapter is a list of review questions to reinforce the information that has been introduced.
Assessment:For some immunology courses, this is unquestionably an excellent choice. Other course directors and faculty might prefer a book with a bit more meat. Students will probably be happy with a book this size and it is certainly easy to read. Most importantly, immunology is a constantly changing discipline and this book is up to date.
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Product Details

  • ISBN-13: 9780721602417
  • Publisher: Elsevier Health Sciences
  • Publication date: 1/19/2004
  • Edition description: Older Edition
  • Edition number: 2
  • Pages: 336
  • Product dimensions: 7.58 (w) x 9.04 (h) x 0.50 (d)

Table of Contents

Chapter 1: Introduction to the Immune System
The Nomenclature, General Properties, and Components of the Immune System

Chapter 2: Innate Immunity
The Early Defense Against Infections

Chapter 3: Antigen Capture and Presentation to Lymphocytes
What Lymphocytes See

Chapter 4: Antigen Recognition in the Adaptive Immune System
Structure of Lymphocyte Antigen Receptors and the Development of Immune Repertoires

Chapter 5: Cell-Mediated Immune Responses
Activation of T Lymphocytes by Cell-Associated Microbes

Chapter 6: Effector Mechanisms of Cell-Mediated Immunity
Eradication of Intracellular Microbes

Chapter 7: Humoral Immune Responses
Activation of B Lymphocytes and Production of Antibodies

Chapter 8: Effector Mechanisms of Humoral Immunity
The Elimination of Extracellular Microbes and Toxins

Chapter 9: Immunologic Tolerance and Autoimmunity
Self-Nonself Discrimination in the Immune System and Its Failure

Chapter 10: Immune Responses Against Tumors and Transplants
Immunity to Noninfectious Transformed and Foreign Cells

Chapter 11: Hypersensitivity Diseases
Disorders Caused by Immune Responses

Chapter 12: Congenital and Acquired Immunodeficiencies
Diseases Caused by Defective Immune Responses

Suggested Readings

Appendix I: Principal Features of CD Molecules

Appendix II: Glossary

Appendix III: Clinical Cases


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