Basic Immunology: Functions and Disorders of the Immune System / Edition 1

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BASIC IMMUNOLOGY emphasizes the fundamental concepts and principles of human immunology that students need to know, without overwhelming them with extraneous material. This entirely new book leads the reader to a firm understanding of basic principles in the field, using full-color illustrations; short, easy-to-read chapters; numerous color tables that summarize key information; clinical cases; and much more — all in a conveniently sized volume that's easier to carry and refer to than a larger, exhaustive text.

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Editorial Reviews

From The Critics
Reviewer:Marion C. Cohen, PhD(University of Medicine and Dentistry of New Jersey-NJMS)
Description:This compact book covers most of the major topics taught in basic immunology courses for medical and dental students. The material is presented in a very concise manner so that the level of detail is limited and some topics receive little attention. The most recent edition was published in 2006.
Purpose:The goal is to present a picture of how the immune system works in a way that allows students to learn basic principles without becoming bogged down in details that are more appropriately covered in advanced courses. Thus the book is limited to what the authors consider the key concepts of the field. Given the increase in information about the immune system, setting limits may be a good thing.
Audience:Medical students studying immunology during their preclinical years are the primary audience, but dental students could also use it.
Features:In addition to trying to cover the major topics that are taught in most medical immunology courses, this book focuses on human immune responses against infectious microbes. Factual details purposely have been limited. Although there are a few clinical cases presented in the appendix, immunologic diseases are presented in the chapters only to emphasize their relation to normal immune responses. Unfortunately, some topics are not covered. For example, there is little about the mucosal immune system, which is different from the peripheral immune system. The figures are presented well, but in some cases they are too complicated and condensed. (They are also available for use by faculty intheir presentations through Elsevier's Student Consult system.) There is also an extensive glossary and a list of the principal features of selected CD markers. At the end of each chapter is a list of review questions to reinforce the information that has been introduced.
Assessment:For some immunology courses, this is unquestionably an excellent choice. Other course directors and faculty might prefer a book with a bit more meat. Students will probably be happy with a book this size and it is certainly easy to read. Most importantly, immunology is a constantly changing discipline and this book is up to date.
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Product Details

  • ISBN-13: 9780721693163
  • Publisher: Elsevier Health Sciences
  • Publication date: 5/1/2001
  • Edition description: Older Edition
  • Edition number: 1
  • Pages: 320
  • Product dimensions: 7.48 (w) x 9.28 (h) x 0.44 (d)

Table of Contents

Introduction to the Immune System: The Nomenclature, General Properties, and Components of the Immune System     1
Innate Immunity: The Early Defense Against Infections     23
Antigen Capture and Presentation to Lymphocytes: What Lymphocytes See     45
Antigen Recognition in the Adaptive Immune System: Structure of Lymphocyte Antigen Receptors and the Development of Immune Repertoires     67
Cell-Mediated Immune Responses: Activation of T Lymphocytes by Cell-Associated Microbes     89
Effector Mechanisms of Cell-Mediated Immunity: Eradication of Intracellular Microbes     113
Humoral Immune Responses: Activation of B Lymphocytes and Production of Antibodies     131
Effector Mechanisms of Humoral Immunity: The Elimination of Extracellular Microbes and Toxins     153
Immunological Tolerance and Autoimmunity: Self-Nonself Discrimination in the Immune System and Its Failure     173
Immune Responses Against Tumors and Transplants: Immunity to Noninfectious Transformed and Foreign Cells     189
Hypersensitivity: Disorders Caused by Immune Responses     205
Congenital and Acquired Immunodeficiencies: Diseases Caused by Defective Immune Responses     223
Suggested Readings     239
Glossary     245
Principal Features of CD Molecules     273
Clinical Cases     283
Index     293
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