Biochemistry / Edition 4

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The "Gold Standard" in Biochemistry text books, Biochemistry 4e, is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge.

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Editorial Reviews

An opulent and expansive comprehensive textbook for students who have had the equivalent of one year of college chemistry and at least one semester of organic chemistry, as well as a one-year college course in general biology in which elementary biochemical concepts were discussed. This edition is updated throughout to keep pace with recent research advances, particularly in nucleic acid and protein structure. It also features an increased emphasis on human disease, more extensive use of molecular biological techniques, and striking new molecular graphics illustrations. Annual supplements are available on a subscription basis. Annotation c. Book News, Inc., Portland, OR
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Product Details

  • ISBN-13: 9780470570951
  • Publisher: Wiley
  • Publication date: 12/14/2010
  • Edition description: New Edition
  • Edition number: 4
  • Pages: 1520
  • Sales rank: 370,531
  • Product dimensions: 8.90 (w) x 11.10 (h) x 2.20 (d)

Meet the Author

Donald Voet received a Ph.D. in chemistry from HarvardUniversity and did postdoctoral research in the Biology Departmentat MIT. Don took up a faculty position in the department ofchemistry at the University of Pennsylvania, upon completing hispostdoctoral work. He has been a visiting scholar at OxfordUniversity, the University of California San Diego, and theWeismann Institute of Science in Israel.

Judith Voet received her Ph.D. from Brandeis Universityand did postdoctoral research at the University of Pennsylvania,Haverford College and the Fox  Chase Cancer Center. She taughtat the University of Delaware before moving to Swarthmore College.Together with Don Voet, she is Co-Editor-in-Chief of the journalBiochemistry and Molecular Biology Education.

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Table of Contents

Guide to Media Resources xvi


1 Life 3

2 Aqueous Solutions 40

3 Thermodynamic Principles: A Review 52


4 Amino Acids 67

5 Nucleic Acids, Gene Expression, and Recombinant DNA Technology82

6 Techniques of Protein and Nucleic Acid Purifications 129

7 Covalent Structures of Proteins and Nucleic Acids 163

8 Three-Dimensional Structures of Proteins 221

9 Protein Folding, Dynamics, and Structural Evolution 278

10 Hemoglobin: Protein Function in Microcosm 323

11 Sugars and Polysaccharides 359

12 Lipids and Membranes 386


13 Introduction to Enzymes 469

14 Rates of Enzymatic Reactions 482

15 Enzymatic Catalysis 506


16 Introduction to Metabolism 559

17 Glycolysis 593

18 Glycogen Metabolism 638

19 Signal Transduction 671

20 Transport through Membranes 744

21 Citric Acid Cycle 789

22 Electron Transport and Oxidative Phosphorylation 823

23 Other Pathways of Carbohydrate Metabolism 871

24 Photosynthesis 901

25 Lipid Metabolism 940

26 Amino Acid Metabolism 1019

27 Energy Metabolism: Integration and Organ Specialization1088

28 Nucleotide Metabolism 1107


29 Nucleic Acid Structures 1145

30 DNA Replication, Repair, and Recombination 1173

31 Transcription 1260

32 Translation 1338

33 Viruses: Paradigms for Cellular Function W-1

34 Eukaryotic Gene Expression W-53

35 Molecular Physiology W-165

(Chapters 33–35 are available on our website,


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Customer Reviews

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Sort by: Showing all of 3 Customer Reviews
  • Posted April 16, 2013

    Cutting edge biochemistry as it applies to the origins of life,

    Cutting edge biochemistry as it applies to the origins of life, as it functions today and as it relates to evolution of life on earth. A must have for your library if you have a passion for the physical and natural science of life.

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    Posted August 26, 2013

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    Posted December 25, 2013

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