Biochemistry of Signal Transduction and Regulation / Edition 4

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Overview

This all-new edition of a best-selling text has been thoroughly updated to keep pace with the rapid progress in signal transduction research.
With didactic skill and clarity, the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis is made transparent for everyone with a basic knowledge in biochemistry or molecular biology.

"Valuable up-to-date information on biochemistry of signal transduction and regulation" (AFS)

"The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry)

"This book is actually two books: Regulation and Signal Transduction." (Drug Research)

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Editorial Reviews

From the Publisher
“This book offers a very nice general overview of the current knowledge of signal transduction and regulation. The author has done an excellent job of assimilating an inherently complicated subject into clear, simple, and logical descriptions.” (The Quarterly Review of Biology, June 2009)

"Krauss has set out to update a general resource for those with interest in signal transduction. The addition of an introductory chapter (Ch.1) makes this edition well pitched to undergraduate with some knowledge of cell biology and biochemistry and would serve as a suitable textbook for an upper-level undergraduate course in this area. the text would also be a useful reference to beginning graduate students in signal transaction and a ready compliment to course that rely on primary literature for course discussions. For instructors, this book would make an excellent companion for teaching signal transduction, as the figures are well laid out and illustrate clearly many points." (Biochemistry and Molecular Biology Education, September/October 2008)

"Well pitched to undergraduates with some knowledge of cell biology and biochemistry and would serve as a suitable textbook for an upper-level undergraduate course in this area.  The text would also be a useful reference to beginning graduate students in signal transduction and a ready compliment to courses that rely on primary literature for course discussions.  For instructors, this book would make an excellent companion for teaching signal transduction, as the figures are well laid out and illustrate clearly many key points." (Biochemistry and Molecular Biology Education, September/October 2008)

From The Critics
A course text for students of biochemistry, biology, and chemistry that describes the structural and biochemical properties of signaling molecules and their regulation, and the interaction of signaling proteins at the various levels of signal transduction. It also examines the basic principles of cellular communication. The 1999 English edition was translated from a 1997 German original. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9783527313976
  • Publisher: Wiley
  • Publication date: 3/14/2008
  • Edition description: 4th, Enlarged and Improved Edition
  • Edition number: 4
  • Pages: 646
  • Product dimensions: 6.75 (w) x 9.45 (h) x 1.30 (d)

Meet the Author

Gerhard Krauss is Professor of Biochemistry at the University of Bayreuth (Germany). His resarch is centered on the mechanism of interaction of DNA binding proteins and their target DNA. He is specifically interested in transcription factor, DNA methyl transferases and nucleotide excision repair.
The idea for a textbook on Signal Transduction and Gene Regulation originated from a lecture course that he has been teaching at Bayreuth since the middle of the 1990s.

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Table of Contents

I Regulation
Regulation of Gene Expression /
Transcriptional Regulation /
Post-transcriptional Regulation /
Regulation of Enyzme Activity

II Signal Transduction Pathways
Structure of Signaling Pathways /
Signaling by Nuclear Receptors /
G Protein-coupled Pathways /
Second Messengers /
Protein Kinases and Phosphatases /
Transmembrane Tyrosine Kinases /
Ras Proteins /
MAP Kinase Pathway

III Control of Cellular Functions
Cell Cycle Regulation /
Apoptosis /
Malfunction of Signaling Pathways /
Oncogenes and Tumor Formation

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Customer Reviews

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