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Biodefense: Principles and Pathogens

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Overview

The anthrax attacks by bioterrorists in the USA in October 2001 served to highlight our vulnerability to biological warfare and to act as an impetus for a massive increase in funding for biodefense research.

In this timely book, top biodefense experts critically review every aspect of this complex issue. The microbiology, diagnosis, pathogenesis, epidemiology, infection control and novel therapeutics for all the key pathogens involved are comprehensively covered. Biodefense is currently focused on anthrax, smallpox, plague, tularemia, botulism and viral hemorrhagic fevers and entire chapters are devoted to each of these topics. Further chapters cover the bioterrorism threat from other diseases including brucellosis, glanders, melioidosis, psittacosis, Q fever, typhoid, gastroenteritis and cryptosporidiosis. Biological toxins derived from living organisms, such as the epsilon toxin derived from Clostridium perfringens, mycotoxins and plant-derived toxins such as ricin are also reviewed in detail. Two fascinating chapters are devoted to agroterrorism, the use of infectious agents that target animals and plants to decimate the food supply. Additional chapters cover emerging pathogens and novel bio-engineered agents that could be used in bioterrorism. The book also covers hospital preparedness, infection control, psychosocial issues, and the evolving methods for surveillance and detection in biodefence.

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Editorial Reviews

Doody's Review Service
Reviewer: Anne L. O'Keefe, MD, MPH (Douglas County NE Health Department)
Description: This edited book provides a scholarly overview of topics such as public health preparedness, community medical response planning, and recognition and management of diseases affecting humans, animals, and plants.
Purpose: The book provides practical information about which public health decision-makers and community medical response planners must be knowledgeable. Contributors include state public health officials, graduate public health professors, and academic human medical, veterinary, and agricultural researchers.
Audience: Local and state public health officials, hospital administrators, and others responsible for community medical and psychosocial response planning would benefit greatly by understanding the topics presented. Students who desire to pursue careers in public health and community medical response planning and anyone who desires a better understanding of the complex issues surrounding planning for a public health emergency will find it useful and interesting.
Features: The first part of the book focuses on general issues in public health preparedness on a community level, focusing on public health policy and legal issues, hospital preparedness, surveillance and detection, and psychosocial issues. Of particular interest is a detailed discussion of a hypothetical biological attack scenario. The second and largest part provides clinical overviews of CDC categories A, B, and C biological agents affecting humans. The final section on agroterrorism focuses on agents affecting animals and crops.
Assessment: This book can be added to a growing list of references on biological weapons published since the terrorism attacks on the United States in 2001. It adds a unique state and local perspective on planning that must be accomplished by public health agencies and community medical responders to prepare for a biological attack or other public health emergency.
From the Publisher

Biodefense: Principles and Pathogens is a good primer on current issues on biodefense...It will be a nice addition to any biodefense, infectious disease, or biological library - Journal of the American Biological Safety Association (Vol 10, No. 4, 2005)

This book is an encyclopaedic source of valid data that should not be lacking from the book collections of hospitals, general practitioners and all other with a professional (or national defence) interest in infectious diseases and their complications - FEMS Immunology and Medical Microbiology (Vol 45, 2005)

The book serves as an invaluable planning tool for public health initiatives in major incident management. The sections on public health preparedness, hospital preparedness and surveillance and detection and psychosocial issues in bioterrorism will be of interest to anyone working in emergency and disaster planning - Eastern Mediterranean Health Journal

[This book] adds a unique state and local perspective on planning that must be accomplished by public health agencies and community medical responders to prepare for a biological attack or other public health emergency - Doody Publishing Services

This compilation of topics is the greatest strength of this book, because all of this information is provided in a single-source volume instead of being scattered among many websites, journal articles, and texts - Journal of Clinical Infectious Diseases, 2006:42 (1 March)


3 Stars from Doody
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Product Details

  • ISBN-13: 9781904933120
  • Publisher: Taylor & Francis
  • Publication date: 6/28/2005
  • Edition description: New Edition
  • Pages: 850
  • Product dimensions: 5.90 (w) x 9.30 (h) x 1.80 (d)

Table of Contents

Part I. General issues in Biopreparedness. 1 Introduction. 2. History of Biological Weapons Development and Deployment. 3. Public Health Preparedness. 4. Public Policy and Legal Issues Surrounding Terrorism and Preparedness in the United States. 5. Hospital Preparedness and Infection Control. 6. Surveillance and Detection for Bioterrorism: Traditional and Evolving Methods. 7. Psychosocial Issues in Bioterrorism.

Part II. Diseases Potentially Resulting From an Attack Deploying Agents or Toxins Against Humans. Section 1. CDC Category A Diseases. 8. Anthrax. 9. Botulism. 10. Plague. 11. Smallpox. 12. Tularemia. 13. Viral Hemorrhagic Fevers. Section 2: CDC Category B Diseases. 14. Other Biological and Microbiological Toxins: Staphylococcal Enterotoxin B, Epsilon Toxin of Clostridium Perfringens, Ricin, and Mycotoxins. 15. Diseases Due to other Category B Bacterial Pathogens I: Brucellosis, Glanders, and Melioidosis. 16. Diseases Due to Other Category B Bacterial Pathogens II: Psittacosis, Q Fever, and Typhus. 17. Bioterrorism and Threats to Food Safety: Campylobacter, Salmonella, Shigella, Diarrheagenic Escherichia Coli, and Listeria. 18. Bioterrorism and Threats to Water Safety: Cholera and Cryptosporidiosis. 19. Encephalitis Viruses as Potential Agents of Bioterrorism. Section 3. CDC Category C diseases. 20. Emerging Infectious Diseases. 21. Miscellaneous Threats: Highly Pathogenic Avian Influenza and Novel Bio-engineered Organisms.

Part III. Agroterrorism. 22. Animal Diseases as a Possible Consequence of Biological Attack. 23. Plant Diseases as a Possible Consequence of Biological Attack.

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