Bioenergetics / Edition 3

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Overview

This new edition of Bioenergetics presents a clear and up-to-date explanation of the chemiosmotic theory and covers mitochondria, bacteria, and chloroplasts. It takes account of the many newly determined structures, such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction. This edition includes additional color figures of protein structures and many newly drawn illustrations designed to enable the reader to grasp the fundamental insights that are derived from knowing the structure. Every chapter has been extensively revised and updated and a new chapter on the study of the bioenergetics of mitochondria in the intact cell is included to satisfy the enormous interest in this topic. Written for students and researchers alike, this book is the most current text on the chemiosmotic theory and membrane bioenergetics available.

Author Biography: David G. Nicholls, Buck Institute, Novato, California, U.S.A.

Stuart J. Ferguson, University of Oxford, U.K.

Audience: Undergraduates, graduates, postgraduates, and researchers working in biochemistry and the biological sciences.

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Editorial Reviews

Doody's Review Service
Reviewer: Eugene A Davidson, PhD (Georgetown University School of Medicine)
Description: This update on the general area of bioenergetics has a focus on the components and organization of the electron transport system, but relevant aspects of photo-coupled processes are also discussed. The previous edition was published in 1992.
Purpose: The goal of this book is to provide a contemporary overview of bioenergetics with an emphasis on those processes generating ATP. These are worthwhile objectives and are well met by this edition.
Audience: The audience includes graduate students and fellows working in the area as well as other scientists wishing an update. There is a sufficiency of both basic and detailed material to satisfy a broad readership. The authors work actively in this area and are well qualified.
Features: The introductory chapter reviews the concept of the chemiosmotic theory and includes a brief description of the structure of membrane systems involved in energy transduction. A short section on ion transport is followed by a quantitative discussion of the energetics of such systems and the proton motive mechanism for gradient generation. A large central chapter details the properties of the respiratory chains with a focus on that of higher animals. The ATP synthase is reviewed and the book concludes with an overview of the role of mitochondria in nonrespiratory processes such as apoptosis. Each section includes sufficient detail to allow a sound grasp of the subject. References are adequate although their inclusion only as an appendix lacks convenience. Scientists wishing to refresh their knowledge in this field will find this book of value. It is also to be recommended to those many instructors who lecture on oxidative metabolism but are accustomed to the rather superficial treatment found in most books.
Assessment: Individual aspects of the material in this book may be found in specific review books but this offering has the virtue of integrating the topic well. The time interval between the current edition and the previous one (10 years) has been marked by several major advances, including X-ray structures and a detailed mechanistic analysis of the ATP synthase. Hence, the book is timely as well.
From The Critics
Extensively revised and updated, this text provides current, accurate information on chemiosmotic theory and membrane bioenergetics. Covers the many newly determined protein structures such as ATP synthase and the two photosystems of photosynthesis, that provide molecular insight into chemiosmotic energy transduction, as well as reviewing major advances in the role of the mitochondria in the life and death of the cell. Includes an appendix listing protein structure resources and new color plates and drawings. Annotation c. Book News, Inc., Portland, OR
From the Publisher
"Not only is Bioenergetics 3 comprehensive, but the material is presented in a reassuringly accessible form. ...supremely successful."
-THE BIOCHEMIST (December 2003)
"Bioenergetics 3 is a worthy successor to the second edition, and one that I can enthusiastically recommend."
—Aubrey D.N.J. de Grey University of Cambridge for MITOCHONDRION (2002)

3 Stars from Doody
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Product Details

  • ISBN-13: 9780125181211
  • Publisher: Elsevier Science
  • Publication date: 7/29/2002
  • Edition description: REV
  • Edition number: 3
  • Pages: 288
  • Product dimensions: 6.62 (w) x 9.78 (h) x 0.63 (d)

Table of Contents

Preface
Note to the reader
Glossary
1 Chemiosmotic Energy Transduction 3
2 Ion Transport Across Energy-Conserving Membranes 17
3 Quantitative Bioenergetics: The Measurement of Driving Forces 31
4 The Chemiosmotic Proton Circuit 57
5 Respiratory Chains 89
6 Photosynthetic Generators of Protonmotive Force 157
7 The ATP Synthase 195
8 Metabolite and Ion Transport 219
9 Mitochondria in the Cell 249
References 271
App Protein structures 283
Index 287
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