Bioinformatics and Molecular Evolution / Edition 1

Paperback (Print)
Rent
Rent from BN.com
$47.77
(Save 60%)
Est. Return Date: 06/17/2014
Buy Used
Buy Used from BN.com
$77.61
(Save 34%)
Item is in good condition but packaging may have signs of shelf wear/aging or torn packaging.
Condition: Used – Good details
Used and New from Other Sellers
Used and New from Other Sellers
from $59.48
Usually ships in 1-2 business days
(Save 49%)
Other sellers (Paperback)
  • All (10) from $59.48   
  • New (6) from $64.08   
  • Used (4) from $59.48   

Overview

In the current era of complete genome sequencing, Bioinformatics and Molecular Evolution provides an up-to-date and comprehensive introduction to bioinformatics in the context of evolutionary biology.

This accessible text:

  • provides a thorough examination of sequence analysis, biological databases, pattern recognition, and applications to genomics, microarrays, and proteomics
  • emphasizes the theoretical and statistical methods used in bioinformatics programs in a way that is accessible to biological science students
  • places bioinformatics in the context of evolutionary biology, including population genetics, molecular evolution, molecular phylogenetics, and their applications
  • features end-of-chapter problems and self-tests to help students synthesize the materials and apply their understanding
  • is accompanied by a dedicated website - www.blackwellpublishing.com/higgs - containing downloadable sequences, links to web resources, answers to self-test questions, and all artwork in downloadable format (artwork also available to instructors on CD-ROM).

This important textbook will equip readers with a thorough understanding of the quantitative methods used in the analysis of molecular evolution, and will be essential reading for advanced undergraduates, graduates, and researchers in molecular biology, genetics, genomics, computational biology, and bioinformatics courses.

Read More Show Less

Editorial Reviews

From the Publisher

"Finally, it has arrived: The book I can confidently recommend to my students as the best in the field. That this single book has been able to cover so much is testimony to the dedication and quality of the authors." James McInerney, National University of Ireland

"Much of bioinformatics is based on, yet too often ignores, the underlying principles of molecular evolution. This well-written book provides a description of modern bioinformatics methods while providing the biology and evolutionary theory necessary to understand how, why, and when these methods work. This is essential reading for those interested in being either a bioinformatics developer or an informed user." Richard Goldstein, National Institute for Medical Research

"I like the text's balance; it is rigorous without being too formal, and has an accessible and broad coverage of topics from both a computer science and a biology perspective." Mohammad Zaki, Rensselaer Polytechnic Institute

"This book nicely integrates molecular evolution and bioinformatics, two disciplines that go hand in hand, as rightfully claimed by the authors. Many bioinformatics applications are based on principles of molecular evolution, and to study molecular evolution is unthinkable nowadays without having access to the necessary tools and implementations. This is an excellent book for both undergraduate and graduate students, as well as for anyone who wants to solve problems in molecular evolution and needs to know the practicalities." Yves Van de Peer, Ghent University, Belgium

"This book is actually fun! Fun, very educative, well organised, practical and easy to use...I wish this book had been published long ago." The British Toxicology Society Newsletter, November 2005

"...an excellent and current introduction to classical bioinformatics and an ideal core text for a Master's course in the subject." Comparative and Functional Genomics, November 2005

Read More Show Less

Product Details

  • ISBN-13: 9781405106832
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 7/28/2005
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 384
  • Sales rank: 1,230,150
  • Product dimensions: 7.46 (w) x 9.61 (h) x 0.84 (d)

Meet the Author

Paul Higgs is currently the Canada Research Chair in Biophysics at McMaster University. Previously, he was the course director of the Bioinformatics MSc at Manchester University. He has a PhD in statistical physics from the University of Cambridge. His current research interests include RNA structure and sequence evolution, molecular phylogenetics, theoretical evolutionary biology, and population genetics.

Teresa Attwood is Professor of Bioinformatics at Manchester University, Visiting Fellow at the European Bioinformatics Institute, and author of the PRINTS protein fingerprint database. She has a PhD in biophysics from the University of Leeds, and now teaches national and international courses in bioinformatics. Her current research interests include protein sequence analysis, data visualization, and biomedical text mining.

Read More Show Less

Table of Contents

Preface.

Chapter Plan.

Chapter 1. Introduction: The Revolution in Biological Information.

Chapter 2. Nucleic Acids, Proteins, and Amino Acids.

Chapter 3. Molecular Evolution and Population Genetics.

Chapter 4. Models of Sequence Evolution.

Chapter 5. Information Resources for Genes and Proteins.

Chapter 6. Sequence Alignment Algorithms.

Chapter 7. Searching Sequence Databases.

Chapter 8. Phylogenetic Methods.

Chapter 9. Patterns in Protein Families.

Chapter 10. Probabilistic Methods and Machine Learning.

Chapter 11. Further Topics in Molecular Evolution and Phylogenetics.

Chapter 12. Genome Evolution.

Chapter 13. DNA Microarrays and the 'omes.

Mathematical Appendix.

List of Web address.

Glossary.

Index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)