Bioinformatics: Sequence and Genome Analysis / Edition 1

Bioinformatics: Sequence and Genome Analysis / Edition 1

by David W. Mount, David Mount
     
 

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ISBN-10: 0879696087

ISBN-13: 9780879696085

Pub. Date: 03/28/2001

Publisher: Cold Spring Harbor Laboratory Press

The application of computational methods to DNA and protein science is a new and exciting development in biology. Bioinformatics: Sequence and Genome Analysis is a comprehensive introduction to this emerging field of study. The book has many unique and valuable features:
  • It is written for any biologist who wants to understand methods of sequence and

Overview

The application of computational methods to DNA and protein science is a new and exciting development in biology. Bioinformatics: Sequence and Genome Analysis is a comprehensive introduction to this emerging field of study. The book has many unique and valuable features:

  • It is written for any biologist who wants to understand methods of sequence and structure analysis and how the necessary computer programs work

  • Sequence alignment, structure prediction, phylogenetic and gene prediction, database searching, and genome analysis are clearly explained and amply illustrated

  • Underlying algorithms and assumptions are clearly explained for the non-specialist

  • Examples are presented in simple numerical terms rather than complex formulas and notation

  • Theoretical underpinnings are linked to biological problems and their solutions

  • Extensive tables provide descriptions and Web sources for a broad range of publicly available software
Based on the author's extensive experience as a molecular geneticist and bioinformaticist at the University of Arizona, this is a uniquely educational book, ideal as a laboratory reference for investigators and also as teaching reference for graduate and undergraduate students studying this fast-changing discipline.

Product Details

ISBN-13:
9780879696085
Publisher:
Cold Spring Harbor Laboratory Press
Publication date:
03/28/2001
Edition description:
Older Edition
Pages:
560
Product dimensions:
8.08(w) x 11.02(h) x 1.15(d)

Table of Contents

Preface
Chapter 1. Historical Introduction and Overview
Chapter 2. Collecting and Storing Sequences in the Laboratory
Chapter 3. Alignment of Pairs of Sequences
Chapter 4. Introduction to Probability and Statistical Analysis of Sequence Alignments
Chapter 5. Multiple Sequence Alignment
Chapter 6. Sequence Database Searching for Similar Sequences
Chapter 7. Phylogenetic Prediction
Chapter 8. Prediction of RNA Secondary Structure
Chapter 9. Gene Prediction and Regulation
Chapter 10. Protein Classification and Structure Prediction
Chapter 11. Genome Analysis
Chapter 12. Bioinformatics Programming Using Perl and Perl Modules
Chapter 13. Analysis of Microarrays

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