The Biological Basis of Cancer / Edition 2

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Overview

The text is designed to be used for an undergraduate course on cancer. It covers everything from the molecular to the clinical aspects of the subject, with a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. A glossary of cancer-related terms is included. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students, will find this a most useful text.

The book contains black-and-white illustrations.

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Editorial Reviews

Alvin Telser
This is a basic introductory textbook presenting a wide range of information on the biological characteristics of cancer. It is intended for intermediate to advanced undergraduates who are conversant in the facts and principles of modern cell and molecular biology. It has been a companion to a seminar-like course at the University of Minnesota for nearly 30 years. These are worthy objectives and the book does a fine job of attaining them. It is intended for advanced undergraduates with a strong background in biology, but it would be of interest to many first year medical students, graduate students, or life scientists who are interested in basic information about cancer. The authors are well known pathologists and are experts in the biology of cancer. The book is nicely produced; most of the figures and drawings are well done and easy to understand. The halftone reproductions of pathological specimens (both whole organs and histological specimens) are difficult to interpret since they are in black and white and are of a poor to average quality. Also, the audience using the book would not understand sufficient anatomy and histology to make much sense of them. Still, it is well written and easy to read. It begins with a series of ""letters"" by or about individuals who are suffering from cancer. This places the subject matter of the book in a compelling personal light. There is also an excellent, extensive glossary at the end of the book. This is a well written and interesting book that many nonspecialists will find interesting and educational. The only minor shortcoming is that it would be best used as a supplement to a course, as it is intended. It would also have been usefulto list a number of standard medical texts in biochemistry, cell and molecular biology, and histology that would provide useful background information. This is a reasonably priced book that should be on the shelves of public, college, university, and life science libraries.
From the Publisher
"This is a well written and interesting book that many non-specialists will find interesting and educational."
Immunology

"Excellent introductory text that can be recommended to both undergraduates and postgraduates in the biological sciences."
The Times Higher Education Supplement

"...an excellent textbook aimed at the undergraduate. It is easy to see how a young biology major taking this course could become interested in cancer research or cancer medicine."
Paul P. Carbone, Director Emeritus of the University of Wisconsin Comprehensive Cancer Center

Doody's Review Service
Reviewer: Alvin Telser, PhD (Northwestern University Feinberg School of Medicine)
Description: This is a basic introductory textbook presenting a wide range of information on the biological characteristics of cancer.
Purpose: It is intended for intermediate to advanced undergraduates who are conversant in the facts and principles of modern cell and molecular biology. It has been a companion to a seminar-like course at the University of Minnesota for nearly 30 years. These are worthy objectives and the book does a fine job of attaining them.
Audience: It is intended for advanced undergraduates with a strong background in biology, but it would be of interest to many first year medical students, graduate students, or life scientists who are interested in basic information about cancer. The authors are well known pathologists and are experts in the biology of cancer.
Features: The book is nicely produced; most of the figures and drawings are well done and easy to understand. The halftone reproductions of pathological specimens (both whole organs and histological specimens) are difficult to interpret since they are in black and white and are of a poor to average quality. Also, the audience using the book would not understand sufficient anatomy and histology to make much sense of them. Still, it is well written and easy to read. It begins with a series of "letters" by or about individuals who are suffering from cancer. This places the subject matter of the book in a compelling personal light. There is also an excellent, extensive glossary at the end of the book.
Assessment: This is a well written and interesting book that many nonspecialists will find interesting and educational. The only minor shortcoming is that it would be best used as a supplement to a course, as it is intended. It would also have been useful to list a number of standard medical texts in biochemistry, cell and molecular biology, and histology that would provide useful background information. This is a reasonably priced book that should be on the shelves of public, college, university, and life science libraries.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780521606332
  • Publisher: Cambridge University Press
  • Publication date: 4/30/2006
  • Edition description: REV
  • Edition number: 2
  • Pages: 494
  • Product dimensions: 6.97 (w) x 9.96 (h) x 1.06 (d)

Table of Contents

Preface
Introduction: Letters illustrating clinical aspects of cancer 1
1 The pathology of cancer 14
2 Metastasis 50
3 Carcinogenesis 79
4 Cancer genetics 115
5 Cancer-associated genes 133
6 Cancer in nonhuman organisms 162
7 Epidemiology 181
8 Cancer treatment 218
9 Biotherapy 250
App Description of selected tumors 271
Glossary 299
References 311
Index 373
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