Biological Safety: Principles and Practices / Edition 4

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Overview

Comprehensive coverage of the identification, assessment, and management of biological hazards.
• Presents the essentials for a complete biological safety program, with specific advice on management and implementation issues.
• Covers the identification, assessment, and management of hazardous biological agents and toxins.
• Updates information on laboratory-acquired infections and examines epidemiology and routes of exposure.
• Refers extensively to current NIH, CDC, and other regulations and guidelines.
• Addresses special considerations, from teaching and industrial labs to biosecurity programs.
• Serves as a resource for those involved in biological safety, including program managers, biological safety professionals.
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Editorial Reviews

From The Critics
Reviewer: J. Thomas Pierce, MBBS PhD(Navy Environmental Health Center)
Description: As the subtitle indicates, the editors seek to address both principles of control and the practice of biosafety with this book.
Purpose: "The fourth edition broadens the original scope of the book in the wake of recent untoward events, e.g., the 2002 anthrax letters. It also addresses Select Agent regulations disseminated by the Unites States Centers for Disease Control and Prevention. Notwithstanding other good journal articles and useful websites, this book is a complete syllabus of pertinent information. "
Audience: The editors indicate that it should be used as a resource by biosafety professionals, those who teach, and those who work with pathogenic agents in research, production, and teaching. More than 50 authors contribute the 33 chapters.
Features: Since publication of the third edition, editors Fleming and Hunt have insisted on a useful update to each chapter. This is readily apparent in chapters addressing laboratory variant Creutzfeldt-Jakob disease and infectious disease epidemiology, among others. The book's major sections are organized along the lines of hazard identification (microbial flora, agents, laboratory considerations, and epidemiology); hazard assessment (risk assessment, bacterial pathogens, protozoal, helminthic, mycotic and viral agents, airborne issues, cell lines, allergens and biological toxins); hazard control (design, primary barriers, personal protection, standard precautions, prudent practices, decontamination and shipping biological materials); administrative controls (biological safety program management, compliance, occupational medicine, and measuring effectiveness); and special considerations (biosafety of prion diseases, safety for BSL-4, biosafety and viral gene transfer factors, biosafety in the teaching laboratory and in the pharmaceutical industry, large-scale production of microorganisms, special considerations for agriculture pathogen biosafety and regulatory impacts).
Assessment: There is little doubt that there is a considerable demand for this material. The field of likely coverage, e.g., teaching laboratories, the pharmaceutical industry, large-scale production facilities, and those involving agricultural pathogens is similarly vast. Many of us have at least seen earlier editions, if not used them. Broadly written books devoted to microbiology, infectious disease, or even occupational health are certainly not a good substitute for this book. I think it will find its way into nearly every regulated facility (and most are these days!). I can envision it will be read in its entirety by biohazard specialists, but be of use to a much broader panel of professionals, including physicians, microbiologists, veterinarians, and industrial hygienists, both in the U.S. and abroad.
From The Critics
Reviewer: J. Thomas Pierce, MBBS PhD(Navy Environmental Health Center)
Description: As the subtitle indicates, the editors seek to address both principles of control and the practice of biosafety with this book.
Purpose: "The fourth edition broadens the original scope of the book in the wake of recent untoward events, e.g., the 2002 anthrax letters. It also addresses Select Agent regulations disseminated by the Unites States Centers for Disease Control and Prevention. Notwithstanding other good journal articles and useful websites, this book is a complete syllabus of pertinent information. "
Audience: The editors indicate that it should be used as a resource by biosafety professionals, those who teach, and those who work with pathogenic agents in research, production, and teaching. More than 50 authors contribute the 33 chapters.
Features: Since publication of the third edition, editors Fleming and Hunt have insisted on a useful update to each chapter. This is readily apparent in chapters addressing laboratory variant Creutzfeldt-Jakob disease and infectious disease epidemiology, among others. The book's major sections are organized along the lines of hazard identification (microbial flora, agents, laboratory considerations, and epidemiology); hazard assessment (risk assessment, bacterial pathogens, protozoal, helminthic, mycotic and viral agents, airborne issues, cell lines, allergens and biological toxins); hazard control (design, primary barriers, personal protection, standard precautions, prudent practices, decontamination and shipping biological materials); administrative controls (biological safety program management, compliance, occupational medicine, and measuring effectiveness); and special considerations (biosafety of prion diseases, safety for BSL-4, biosafety and viral gene transfer factors, biosafety in the teaching laboratory and in the pharmaceutical industry, large-scale production of microorganisms, special considerations for agriculture pathogen biosafety and regulatory impacts).
Assessment: There is little doubt that there is a considerable demand for this material. The field of likely coverage, e.g., teaching laboratories, the pharmaceutical industry, large-scale production facilities, and those involving agricultural pathogens is similarly vast. Many of us have at least seen earlier editions, if not used them. Broadly written books devoted to microbiology, infectious disease, or even occupational health are certainly not a good substitute for this book. I think it will find its way into nearly every regulated facility (and most are these days!). I can envision it will be read in its entirety by biohazard specialists, but be of use to a much broader panel of professionals, including physicians, microbiologists, veterinarians, and industrial hygienists, both in the U.S. and abroad.
Booknews
New edition of a text in biosafety that covers the epidemiology of laboratory-associated infections, including some previously unreported cases. Fleming (biosafety consultant) and Hunt (biological safety, Duke U.) present 35 contributions that discuss hazard assessments of the wide range of pathogens and biological toxins encountered in biomedical laboratories as well as other occupational settings, including all facets of hazard control from personal protective equipment to institution-wide provisions. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9781555813390
  • Publisher: ASM Press
  • Publication date: 8/28/2006
  • Edition description: REV
  • Edition number: 4
  • Pages: 680
  • Product dimensions: 8.50 (w) x 11.10 (h) x 1.50 (d)

Table of Contents

Table of Contents

Section I. Hazard Identification

Section Editor: Lynn Harding

1. Microbial Flora of Humans and Microbial Virulence Factors, Paul A. Granato
2. Indigenous and Pathogenic Agents of Research Animals, Diane O. Fleming
3. Laboratory, Growth Chamber, and Greenhouse Microbial Safety: Plant Pathogens and Plant-Associated Microorganisms of Significance to Human Health, Ann K. Vidaver, Sue A. Tolin, and Patricia Lambrecht
4. Epidemiology of Laboratory-Associated Infections, Lynn Harding and Karen Brandt Byers
Section II. Hazard Assessment

Section Editors: Diane O. Fleming and Debra L. Hunt

5. Risk Assessment of Biological Hazards, Diane O. Fleming
6. Bacterial Pathogens, Joseph Coggin, Jr.
7. Protozoa and Helminths, Barbara L. Herwaldt
8. Mycotic Agents of Human Disease, Wiley A. Schell
9. Viral Agents of Human Disease: Biosafety Concerns, Jason P. Paragus and Timothy P. Endy
10. Biosafety for Microorganisms Transmitted Primarily by the Airborne Route, Michael A. Pentella, Pamela A. Kostle, Lucy DesJardin, and Mary J. R. Gilchrist
11. Cell Lines: Applications and Biosafety, Otto Doblhoff-Dier and Glyn Stacey
12. Allergens of Animal and Biological Systems, Wanda Phipatanakul and Robert A. Wood
13. Biological Toxins: Safety and Science, Joseph P. Kozlovac and Robert J. Hawley
Section III. Hazard Control

Section Editors: Elizabeth Gilman Duane and Richard C. Fink

14. Design of Biomedical Laboratory Facilities, Jonathan T. Crane and Jonathan Y. Richmond
15. Other Primary Barriers and Equipment-Associated Hazards, Elizabeth A. Gilman Duane and Richard C. Fink
16. Primary Barriers: Biological Safety Cabinets, Fume Hoods, and Gloves Boxes, David G. Stuart, David C. Eagleson, and Ch. arles W. Quint, Jr.
17. Personal Respiratory Protection, Nicole Vars McCullough
18. Standard (Universal) Precautions for Handling Human Specimens, Debra L. Hunt
19. Prudent Biosafety Practices, Diane O. Fleming
20. Decontamination and Disinfection, Martin S. Favero and Matthew J. Arduino
21. Packaging and Shipping Biological Materials, Larry D. Gray and James w. Snyder
Section IV. Administrative Control

Section Editors: LouAnn Burnett and Janet Peterson

22. Biological Safety Program Management, LouAnn Crawford Burnett
23. Biosafety Compliance: a Global Perspective, Richard Rebar and Halley Moriyama
24. Occupational Medicine in a Biomedical Research Setting, Deborah E. Wilson and James M. Schmidt
25. Measuring Biosafety Program Effectiveness, Janet S. Peterson and Robert J. Hashimoto
Section V. Special Considerations for Biosafety

Section Editors: Mary L. Cipriano and Robert Hawley

26. The Biosafety of Prion Diseases, Henry Baron and Stanley B. Prusiner
27. Safety Considerations in the BSL-4 Maximum Containment Laboratory, David S. Bressler and Robert J. Hawley
28. Biosafety and Viral Gene Transfer Vectors, Thomas A. Kost, Patrick J. Condreay, and Claudia A. Mickelson
29. Biosafety in the Teaching Laboratory, David M. Cariberg and Michael R. Yeaman
30. Biosafety in the Pharmaceutical Industry, Paul J. Meechan, Joseph Gyuris, Brian R. Petuch, Michel M. Chartrain, and Wayne K. Herber
31. Large-Scale Production of Microorganisms, Mary L. Cipriano
32. Special Considerations for Agriculture Pathogen Biosafety, Robert A. Heckert and Joseph P. Kozlovac
33. Biosafety and Biosecurity: Regulatory Impact, Robert J. Hawley and Theresa D. Duley

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