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Biological Safety: Principles and Practices / Edition 3

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Overview

The fourth edition of Biological Safety: Principles and Practices continues the format of the previous edition, focusing closely on infectious and toxic biological agents and their identification and control. Written by authorities with decades of experience in the field, this newest edition examines significant developments throughout the field and discusses current regulations including those handed down from the Centers for Disease Control and Prevention and the U.S. Department of Agriculture.

Chapters outline the human, animal, and agricultural considerations of a wide range of specific biohazards, from pathogenic organisms, viruses, prions, and cell cultures, to toxins and allergens. Numerous chapters detail practical systems for biohazard control. A brand-new chapter details critical safety considerations in a maximum containment (BSL 4) laboratory. Appropriate updates have been made to chapters carried over from the third edition, and a host of new contributors offer fresh perspectives on topics such as packaging and shipping of biological materials.

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Editorial Reviews

Booknews
New edition of a text in biosafety that covers the epidemiology of laboratory-associated infections, including some previously unreported cases. Fleming (biosafety consultant) and Hunt (biological safety, Duke U.) present 35 contributions that discuss hazard assessments of the wide range of pathogens and biological toxins encountered in biomedical laboratories as well as other occupational settings, including all facets of hazard control from personal protective equipment to institution-wide provisions. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Doody's Review Service
Reviewer: J. Thomas Pierce, MBBS PhD(Navy Environmental Health Center)
Description: As the subtitle indicates, the editors seek to address both principles of control and the practice of biosafety with this book.
Purpose: The fourth edition broadens the original scope of the book in the wake of recent untoward events, e.g., the 2002 anthrax letters. It also addresses Select Agent regulations disseminated by the Unites States Centers for Disease Control and Prevention. Notwithstanding other good journal articles and useful websites, this book is a complete syllabus of pertinent information.
Audience: The editors indicate that it should be used as a resource by biosafety professionals, those who teach, and those who work with pathogenic agents in research, production, and teaching. More than 50 authors contribute the 33 chapters.
Features: Since publication of the third edition, editors Fleming and Hunt have insisted on a useful update to each chapter. This is readily apparent in chapters addressing laboratory variant Creutzfeldt-Jakob disease and infectious disease epidemiology, among others. The book's major sections are organized along the lines of hazard identification (microbial flora, agents, laboratory considerations, and epidemiology); hazard assessment (risk assessment, bacterial pathogens, protozoal, helminthic, mycotic and viral agents, airborne issues, cell lines, allergens and biological toxins); hazard control (design, primary barriers, personal protection, standard precautions, prudent practices, decontamination and shipping biological materials); administrative controls (biological safety program management, compliance, occupational medicine, and measuring effectiveness); and special considerations (biosafety of prion diseases, safety for BSL-4, biosafety and viral gene transfer factors, biosafety in the teaching laboratory and in the pharmaceutical industry, large-scale production of microorganisms, special considerations for agriculture pathogen biosafety and regulatory impacts).
Assessment: There is little doubt that there is a considerable demand for this material. The field of likely coverage, e.g., teaching laboratories, the pharmaceutical industry, large-scale production facilities, and those involving agricultural pathogens is similarly vast. Many of us have at least seen earlier editions, if not used them. Broadly written books devoted to microbiology, infectious disease, or even occupational health are certainly not a good substitute for this book. I think it will find its way into nearly every regulated facility (and most are these days!). I can envision it will be read in its entirety by biohazard specialists, but be of use to a much broader panel of professionals, including physicians, microbiologists, veterinarians, and industrial hygienists, both in the U.S. and abroad.
From The Critics
Reviewer: J. Thomas Pierce, MBBS PhD(Navy Environmental Health Center)
Description: As the subtitle indicates, the editors seek to address both principles of control and the practice of biosafety with this book.
Purpose: "The fourth edition broadens the original scope of the book in the wake of recent untoward events, e.g., the 2002 anthrax letters. It also addresses Select Agent regulations disseminated by the Unites States Centers for Disease Control and Prevention. Notwithstanding other good journal articles and useful websites, this book is a complete syllabus of pertinent information. "
Audience: The editors indicate that it should be used as a resource by biosafety professionals, those who teach, and those who work with pathogenic agents in research, production, and teaching. More than 50 authors contribute the 33 chapters.
Features: Since publication of the third edition, editors Fleming and Hunt have insisted on a useful update to each chapter. This is readily apparent in chapters addressing laboratory variant Creutzfeldt-Jakob disease and infectious disease epidemiology, among others. The book's major sections are organized along the lines of hazard identification (microbial flora, agents, laboratory considerations, and epidemiology); hazard assessment (risk assessment, bacterial pathogens, protozoal, helminthic, mycotic and viral agents, airborne issues, cell lines, allergens and biological toxins); hazard control (design, primary barriers, personal protection, standard precautions, prudent practices, decontamination and shipping biological materials); administrative controls (biological safety program management, compliance, occupational medicine, and measuring effectiveness); and special considerations (biosafety of prion diseases, safety for BSL-4, biosafety and viral gene transfer factors, biosafety in the teaching laboratory and in the pharmaceutical industry, large-scale production of microorganisms, special considerations for agriculture pathogen biosafety and regulatory impacts).
Assessment: There is little doubt that there is a considerable demand for this material. The field of likely coverage, e.g., teaching laboratories, the pharmaceutical industry, large-scale production facilities, and those involving agricultural pathogens is similarly vast. Many of us have at least seen earlier editions, if not used them. Broadly written books devoted to microbiology, infectious disease, or even occupational health are certainly not a good substitute for this book. I think it will find its way into nearly every regulated facility (and most are these days!). I can envision it will be read in its entirety by biohazard specialists, but be of use to a much broader panel of professionals, including physicians, microbiologists, veterinarians, and industrial hygienists, both in the U.S. and abroad.
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Product Details

  • ISBN-13: 9781555811808
  • Publisher: American Society Microbiology
  • Publication date: 1/1/2000
  • Edition description: REVISED
  • Edition number: 3
  • Pages: 784
  • Product dimensions: 8.68 (w) x 11.28 (h) x 1.61 (d)

Table of Contents

I Hazard identification
1 Microbial flora of humans and microbial virulence factors 3
2 Indigenous and pathogenic agents of research animals 19
3 Laboratory, growth chamber, and greenhouse microbial safety : plant pathogens and plant-associated microorganisms of significance to human health 35
4 Epidemiology of laboratory-associated infections 53
II Hazard assessment
5 Risk assessment of biological hazards 81
6 Bacterial pathogens 93
7 Protozoa and helminths 115
8 Mycotic agents of human disease 163
9 Viral agents of human disease : biosafety concerns 179
10 Biosafety for microorganisms transmitted primarily by the airborne route 209
11 Cell lines : applications and biosafety 221
12 Allergens of animal and biological systems 241
13 Biological toxins : safety and science 253
III Hazard control
14 Design of biomedical laboratory facilities 273
15 Primary barriers and equipment-associated hazards 295
16 Primary barriers : biological safety cabinets, fume hoods, and glove boxes 303
17 Personal respiratory protection 325
18 Standard (universal) precautions for handling human specimens 341
19 Prudent biosafety practices 361
20 Decontamination and disinfection 373
21 Packing and shipping biological materials 383
IV Administrative controls
22 Biological safety program management 405
23 Biosafety compliance : a global perspective 417
24 Occupational medicine in a biomedical research setting 437
25 Measuring biosafety program effectiveness 445
V Special considerations for biosafety
26 Biosafety of prion diseases 461
27 Safety considerations in the BSL-4 maximum-containment laboratory 487
28 Biosafety and viral gene transfer vectors 509
29 Biosafety in the teaching laboratory 531
30 Biosafety in the pharmaceutical industry 551
31 Large-scale production of microorganisms 561
32 Special considerations for agriculture pathogen biosafety 579
33 Biosafety and biosecurity : regulatory impact 587
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