Biology of Aging: Observations and Principles

by Robert Arking

Overview

Text on the physiology of aging. Topics include: defining and measuring aging, changes in populations, genetic determinants of longevity, altering aging, and aging as an intracellular process. For advanced medical students, researchers, and practitioners.

Product Details

ISBN-13:	9780199727629
Publisher:	Oxford University Press
Publication date:	02/02/2006
Sold by:	Barnes & Noble
Format:	eBook
File size:	7 MB

About the Author

Robert Arking is a Professor of Biological Sciences at Wayne State University. His research involves the mechanisms underlying the onset of senescenece in Drosophila.

Table of Contents

PART I: What Is Aging?1. Perspectives on Aging2. Measuring Age-related Changes in Populations3. Measuring Age-related Changes in IndividualsPART II: Why Do We Age?4. Evolutionary and Comparative Aspects of Longevity and SenescencePART III: How Do We Age?5. Human Aging6. Altering Aging: Interventions That Modify Longevity and Senescence7. Genetic Determinants of Longevity in Animal Models8. Genetic and Social Aspects of Aging in HumansPART IV: What Is the Mechanistic Basis of Aging and Senscence?9. Mechanisms Underlying the Transition from Health to Senescence10. Stochastic Theories of Aging11. Systemic Theories of Senescence12. Senescence as a Breakdown of Intracellular Regulatory Processes13. Senescence as a Breakdown of Intercellular Regulatory ProcessesPART V: An Integrated Theory of Aging14. A Theory of Aging over the Life SpanPART VI: What Can We Do about Aging?15. Aging-related Research and Its Impact on Society

Editorial Reviews

New edition of a text that provides an overview of biological aging processes at the molecular, cellular, organismal, and population levels and in a comparative and evolutionary context. An important conceptual change in this edition is that rather than viewing age- related diseases as being an abnormal way to age, the author now treats diseases as "systemic failures that highlight the weak points of the evolved anatomical and physiological design of the organism and thereby allow us to identify and investigate them." Annotation c. by Book News, Inc., Portland, Or.

Booknews

"This third edition is a timely and important contribution that compiles historical and recent research findings in a highly readable form and, as well, tackles some of the difficult conceptual problems in understanding aging"—American Journal of Human Biology

From the Publisher