The Biology of Cancer is a new textbook for undergraduate and graduate biology students as well as medical students studying the molecular and cellular bases of cancer. The book presents the principles of cancer biology in an organized, cogent, and in-depth manner. The clarity of writing and the lucid full-color art program make the book accessible and engaging. The information unfolds through the presentation of key experiments, which give readers a sense of discovery, and provide insights into the conceptual foundation underlying modern cancer biology. A CD-ROM packaged with the book contains figures from the book, additional sidebars from the text, movies, and audio files of mini-lectures.
Besides its value as a textbook, The Biology of Cancer will be a useful reference for individuals working in biomedical laboratories and for clinicians.
his is [an] excellent textbook on the basic biology of cancer.
There is no comparable text in cancer biology and no single book that is so current and informative.
— November 30, 2006, Vol 444
The Biology of Cancer is no doubt the definitive statement on its topic today.
Nature Cell Biology
The breadth of the topics covered, the clear writing style, the logical organization and the beautiful figures make The Biology of Cancer a classic text for any biologist interested in cancer . . . .An additional strength of the book is the multimedia CD . . . Thus, The Biology of Cancer is not only a great read but also an outstanding learning tool.
From The Critics
Reviewer: Chonghui Cheng, MD PhD(Northwestern University Feinberg School of Medicine) Description: This book describes contemporary cancer biology in an organized, clear fashion. The previous edition was published in 2007. Purpose: It is designed to provide a framework of conceptual cancer biology. The book fulfills its purpose and is, indeed, a must-read for students of cancer biology. Audience: Written for the next generation of cancer researchers, the book also is a great resource for faculty who wish to move their research directions to cancer biology. The author is an internationally renowned cancer biologist. Features: This book covers many aspects of cancer biology, from the discovery of oncogenes to cancer initiation, metastasis, and treatment. This book provides up-to-date information on cancer research in an easy-to-follow and in-depth manner. Assessment: This is a high quality book for the next generation of cancer biologists. It includes updated information and concepts in cancer research that justify replacing the previous edition.
Dr. Robert A. Weinberg is a founding member of the Whitehead Institute for Biomedical Research. He is the Daniel K. Ludwig Professor for Cancer Research and the American Cancer Society Research Professor at the Massachusetts Institute of Technology (MIT). Dr. Weinberg is an internationally recognized authority on the genetic basis of human cancer and was awarded the U.S. National Medal of Science by President Clinton in 1997.
Chapter 1: The Biology and Genetics of Cells and Organisms
Chapter 2: The Nature of Cancer
Chapter 3: Tumor Viruses
Chapter 4: Cellular Oncogenes
Chapter 5: Growth Factors and Their Receptors
Chapter 6: Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer
Chapter 7: Tumor Suppressor Genes
Chapter 8: pRb and Control of the Cell Cycle Clock
Chapter 9: p53 and Apoptosis: Master Guardian and Executioner
Chapter 10: Eternal Life: Cell Immortalization and Tumorigenesis
Chapter 11: Multistep Tumorigenesis
Chapter 12: Maintenance of Genomic Integrity and the Development ofCancer
Chapter 13: Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis
Chapter 14: Moving Out: Invasion and Metastasis
Chapter 15: Crowd Control: Tumor Immunology and Immunotherapy
Chapter 16: The Rational Treatment of Cancer