Biology of the Lysosome / Edition 1

by John B. Lloyd, Robert W. Mason

Overview

Volume 27 provides a comprehensive review of current knowledge of lysosome function in mammalian cells. The book's unique contribution is its series of chapters that offers unparalleled treatment of the metabolic activities of lysosomes.

Product Details

ISBN-13:	9781461376743
Publisher:	Springer US
Publication date:	11/05/2012
Series:	Subcellular Biochemistry , #27
Edition description:	1996
Pages:	416
Product dimensions:	5.98(w) x 9.02(h) x 0.04(d)

Table of Contents

I: Delivery Routes to the Lysosome.- 1 The Taxonomy of Lysosomes and Related Structures.- 2 Origin of Lysosomal Proteins.- 3 Endocytosis.- 4 Autophagy.- 5 Selective Proteolysis: 70-kDa Heat-Shock Protein and Ubiquitin-Dependent Mechanisms?.- II: Metabolism in the Lysosome.- 6 Lysosomal Metabolism of Proteins.- 7 Lysosomal Metabolism of Glycoconjugates.- 8 Lysosomal Metabolism of Lipids.- 9 Lysosomal Nucleic Acid and Phosphate Metabolism and Related Metabolic Reactions.- III: The Lysosome in Its Cytoplasmic Environment.- 10 Acidification of Lysosomes and Endosomes.- 11 Metabolite Efflux and Influx across the Lysosome Membrane.- 12 Lysosome Pharmacology and Toxicology.

Editorial Reviews

From a preview of a previous volume:
‘The heterogeneity of topics...is very ambitious, and the result is, overall, successful because of the high quality of the individual contributions...highly recommended.'
Amercian Scientist.

‘Well written and timely...of interest to all those involved in the study of this organelle and for those interested in the medical and genetic aspects of lysosomal disorders...recommended.'
Journal of Medical Genetics

From the Publisher