Biomat 2005: Proceedings of the International Symposium on Mathematical and Computational Biology

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This volume contains the contributions of the keynote speakers to the BIOMAT 2005 symposium, as well as a collection of selected papers by pioneering researchers. It provides a comprehensive review of the mathematical modeling of cancer development, Alzheimer’s disease, malaria, and aneurysm development. Various models for the immune system and epidemiological issues are analyzed and reviewed. The book also explores protein structure prediction by optimization and combinatorial techniques (Steiner trees). The ...
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More About This Book

Overview

This volume contains the contributions of the keynote speakers to the BIOMAT 2005 symposium, as well as a collection of selected papers by pioneering researchers. It provides a comprehensive review of the mathematical modeling of cancer development, Alzheimer’s disease, malaria, and aneurysm development. Various models for the immune system and epidemiological issues are analyzed and reviewed. The book also explores protein structure prediction by optimization and combinatorial techniques (Steiner trees). The coverage includes bioinformatics issues, regulation of gene expression, evolution, development, DNA and array modeling, and small world networks.
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Product Details

  • ISBN-13: 9789812567970
  • Publisher: World Scientific Publishing Company, Incorporated
  • Publication date: 4/28/2006
  • Pages: 408
  • Product dimensions: 6.30 (w) x 8.90 (h) x 1.10 (d)

Table of Contents

Modelling aspects of vascular cancer development 1
Cellular automaton modelling of biological pattern formation 13
A mathematical analysis of cylindrical shaped aneurysms 35
On the origin of metazoans 49
A software tool to model genetic regulatory networks : applications to segmental patterning in drosophila 71
The mitochondrial eve in an exponentially growing population and a critique to the Out of Africa model for human evolution 89
A neurocomputational model of the role of cholesterol in the process of Alzheimer's disease 103
Theoretical study of a biofilm life cycle : growth, nutrient depletion and detachment 119
Optimal control of distributed systems applied to the problems of ambient pollution 131
Modeling the in vivo dynamics of viral infections 153
Short and long-term dynamics of childhood diseases on dynamic small-world networks 171
Clonal expansion of cytotoxic T cell clones : the role of the immunoproteasome 199
Modeling plague dynamics : endemic states, outbreaks and epidemic waves 213
The basic reproductive rate in the malaria model 231
Epidemiological model with fast dispersion 245
Structure prediction of alpha-helical proteins 265
Quality and effectiveness of protein structure comparative models 289
Steiner minimal trees, twist angles, and the protein folding problem 299
Steiner trees as intramolecular networks of the biomacromolecular structures 327
Exploring chemical space with computers : informatics challenges for AI and machine learning 343
Optimization of between group analysis of gene expression disease class prediction 351
On biclustering with features selection for microarray data sets 367
Simple and effective classifiers to model biological data 379
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