Biomaterials in Modern Medicine: The Groningen Perspective

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This useful book is written from a medical perspective and is aimed at academics as well as medical and biomedical engineering students who want to become involved in the design, development, manufacturing or use of prostheses or medical devices. It covers basic information on the complexities of implant and medical device development. The design process, technology assessment, animal experiments, histocompatibility, tissue compatibility and infections are described. In addition, examples of biomaterial applications are presented, showing the diversity of biomaterials. This is the first book that guides the reader through the complicated process of medical product development. Different technical and medical aspects of medical implants are highlighted by a group of authors who are actively involved in biomaterial research at the University Medical Center of Groningen, one of the leading hospitals in The Netherlands.

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Product Details

  • ISBN-13: 9789812709561
  • Publisher: World Scientific Publishing Company, Incorporated
  • Publication date: 2/28/2008
  • Pages: 280
  • Product dimensions: 6.10 (w) x 9.00 (h) x 0.60 (d)

Table of Contents

List of Contributors     vii
Introduction   J.P.A. Nicolai   G. Rakhorst     1
Design of Biomedical Products   G.J. Verkerke   E.B. van der Houwen     23
Animal Models in Biomaterials Research   G. Rakhorst   E.J.O. ten Hallers   C.M.A. Thuring     39
Technology Assessment   J.M. Hummel     55
Haemocompatibility of Medical Devices   W. van Oeveren     67
Tissue and Cell Interactions with Materials   T.G. van Kooten   R. Kuijer     93
Biomaterial-associated Surgery and Infection - A Review of the Literature   P.G.M. Maathuis   S.K. Bulstra   H.C. van der Mei   J.R. van Horn   H.J. Busscher     119
Cardiopulmonary Bypass and Postoperative Organ Dysfunction   Y. John Gu     139
Mechanical Circulatory Support Systems   G. Rakhorst   M.E. Erasmus     153
Biomaterial-related Infections in Orthopedic Implants   D. Neut   R.L. Diercks     169
Biomaterials for Voice Reconstruction   G.J. Verkerke   J.W. Tack   I.F. Herrmann   H.F. Mahieu   B.F.A.M. van der Laan   H.K. Schutte     191
Biomaterials in Ophthalmology   S.A. Koopmans   V.W. Renardel de Lavalette     209
Biomaterials in Plastic Surgery   M.F. Meek     229
Surgical Meshes - Morphology-dependent Bacterial Colonization   A.F. Engelsman     241
Index     265

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