Biomedical Applications of Computer Modeling

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The book represents the first single-volume book that describes genera l approaches to computer modeling as they apply to the biomedical prof essions, particularly in the realms of pharmacology and biochemistry. Bringing together contributions from researchers with hands-on experti se, the book is loaded with examples, and it also encompasses differen t types of computer modeling approaches. In fact, the text supports ea ch modeling approach with clinical examples. It thereby provides a con venient source of readily applicable modeling information. In addition , the book offers easy-to-follow information and presents it in a how- to manner that minimizes the use of mathematical jargon.

The book contains black-and-white illustrations.

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Editorial Reviews

Now that computers and modelling software have become as ubiquitous and cheap in the biomedical environment as, say, ashtrays were a few decades ago, experienced researchers decided it was time to update the literature on modelling to fit the new situation. With minimal mathematical jargon, they demonstrate how to use the common software packages to create models that provide insight into biological mechanisms, and how to design better experiments, describing a range of different approaches to computer modeling and supporting each with practical examples. Annotation c. Book News, Inc., Portland, OR (
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Product Details

Table of Contents

The Pharmacological Consequences of Modeling Synoptic Receptor Systems
The Ternary Complex Model
From the Static to the Dynamic: 3 Models of Signal Transduction in G Protein Coupled Receptors
Intramolecular Dynamics and Ligand-Induced Conformational Changes: A Stochastic Model of Receptor Action
Linking Bioinformatics and Cheminformatics: From Genes to Structure-Activity Relationships
Computer-Intensive Statistical Procedures
Beyond Eyeballing: Fitting Models to Experimental Data

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