Biomedical Imaging in Experimental Neuroscience

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Emphasizing data analysis and interpretation, Biomedical Imaging in Experimental Neuroscience presents a comprehensive review of the non-invasive biomedical imaging techniques available for laboratory animal research. It covers the scope and limitations of these methods and analyzes their impact on in vivo neuroscience research. The book also provides a concise theoretical description of the pertinent physics. Presents a detailed review of the application of biomedical imaging techniques available for non-invasive laboratory animal research Emphasizes the versatility of MRI in experimental neuroscience research - from anatomy to function Provides concise, theoretical descriptions of physics with the biologist in mind Serves as a practical guide with focus on application and implementation

Recent years have seen an explosion of activity in the field of biomedical imaging in an attempt to understand the behavior of the brain in healthy and disease states. With the emergence of genetically manipulated laboratory mice and the knowledge of the mouse genome, we are entering an exciting new era with revolutionary tools for experimental research. Non-invasive imaging techniques capable of providing both anatomical and functional descriptions of the brain have become essential. Among the various imaging methodologies, magnetic resonance imaging (MRI) stands forefront by virtue of its contrast versatility and pathophsyiological specificity.Emphasizing the relationship between physiological microenvironment and macroscopic imaging signal changes, Biomedical Imaging in Experimental Neuroscience presents a comprehensive review of the non-invasive biomedical imaging techniques available for laboratory animal research. Focusing on MRI, but recognizing the multiple forms of imaging information, this book outlines the scope and limitations of these methods and analyzes their impact on in vivo neuroscience research. The book is intended for the biologist who may not have a background in the physical sciences. This applied guide also provides a concise theoretical description of the pertinent physics. Non-invasive imaging offers the obvious benefits of reducing sample sizes and identifying new and unanticipated behaviors. Biomedical Imaging in Experimental Neuroscience presents detailed information for biologists interested in how biomedical imaging may augment their in vivo research and for clinical practitioners seeking deeper insights into the association between imaging findings anddisease pathophysiology.

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Editorial Reviews

Doody's Review Service
Reviewer: Celso Agner, MD, MS, MSc (Michigan Neurology Partners)
Description: Visualization in neuroscience has progressed tremendously since Cajal's times. The ability to represent seen images accurately has permitted a major jump in microscopy. A book on biomedical visualization is, therefore, justified.
Purpose: The purpose of this book is to address different aspects of imaging as applied to neuroscience. This worthy objective is clearly met by recognized scientists in the field.
Audience: Neuroscientists, neurologists, and neurosurgeons are the targeted readers for this book.
Features: Twenty-one authors contribute 11 chapters in this well-written, 351-page book. The chapters encompass all aspects of pertinent neuroanatomy, neurophysiology, and neuropathology, with a comparison of all imaging modalities available for clinical practice. The illustrations are of very good quality, the tables and graphs, pertinent to the text, and the references, up-to-date. The index is very helpful.
Assessment: Neuroscientists, neurologists, and neurosurgeons alike will find new information on possible imaging modalities to be applied to their research. This is an essential book for medical libraries in neuroscience, neurology, and neurosurgery.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780849301223
  • Publisher: Taylor & Francis
  • Publication date: 12/28/2002
  • Series: Frontiers in Neuroscience Series
  • Pages: 368
  • Product dimensions: 6.40 (w) x 9.50 (h) x 1.00 (d)

Table of Contents

Principles of MRI Contrast, Tim Roberts and Nick van Bruggen

MRI Measurement of Cerebral Perfusion and Application to Experimental Neuroscience, Mark F. Lythgoe, D.L.Thomas, and F. Calamante

MRI Measurement of Cerebral Water Diffusion and Its Application to Experimental Research, Richard A. D. Carano, Nick van Bruggen and Alex J. de Crespigny

Functional Magnetic Resonance Imaging, Mathias Höehn.

Functional Imaging in Nonhuman Primates, Elizabeth Disbrow

Pharmacologic Magnetic Resonance Imaging (phMRI), Bruce G. Jenkins, Yin-Ching Iris Chen, and Joseph B. Mandeville

Anatomical Studies in the Rodent Brain and Spinal Cord: Applications of Magnetic Resonance Microscopy, Helene Benveniste, Tom Mareci, and Steve Blackband

Magnetic Resonance Spectroscopy: Principles and Applications, Stephen R. Williams and Nicola R. Sibson.

Small Animal Imaging with Positron Emission Tomography, Simon Cherry and Harley Kornblum

MRI and Novel Contrast Agents for Molecular Imaging, Michel M. Modo and Steven C.R. Williams

The Future for Biomedical Imaging: Emerging and Alternative Technologies, Nick van Bruggen and Tim Roberts

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