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Biophysical Analysis of Membrane Proteins: Investigating Structure and Function / Edition 1
     

Biophysical Analysis of Membrane Proteins: Investigating Structure and Function / Edition 1

by Eva Pebay-Peyroula
 

ISBN-10: 3527316779

ISBN-13: 9783527316779

Pub. Date: 12/21/2007

Publisher: Wiley

Meeting the need for a book on developing and using new methods to investigate membrane proteins, this is the first of its kind to present the full range of novel techniques in one resource. Top researchers from around the world focus on the physical principles exploited in the different techniques, and provide examples of how these can bring about important new

Overview

Meeting the need for a book on developing and using new methods to investigate membrane proteins, this is the first of its kind to present the full range of novel techniques in one resource. Top researchers from around the world focus on the physical principles exploited in the different techniques, and provide examples of how these can bring about important new insights.
Following an introduction, further sections discuss structural approaches, molecular interaction and large assemblies, dynamics and spectroscopies, finishing off with an exploration of structure-function relationships in whole cells.

Product Details

ISBN-13:
9783527316779
Publisher:
Wiley
Publication date:
12/21/2007
Pages:
368
Product dimensions:
6.90(w) x 9.70(h) x 0.94(d)

Table of Contents

Introduction
STRUCTURAL APPROACHES
Membrane Protein Structure Determination by Electron Cryo-microscopy
NMR Liquid or Solid State
MOLECULAR INTERACTION AND LARGE ASSEMBLIES
Analytical Ultracentrifugation: Membrane Protein Assemblies in the Presence of Detergent
SPR Biosensors for Characterizing Membrane-associated Proteins
Atomic Force Microscopy (AFM): High Resolution Imaging of Structure and Assembly of Membrane Proteins
DYNAMICS
Molecular Dynamics Simulations
Understanding Structure and Function of Membrane Proteins Using Free Energy Calculations
Neutron Scattering to Study Membrane Structure and Dynamics
SPECTROSCOPIES
Circular Dichroism: Folding and Conformational Changes of Membrane Proteins
Membrane Protein Structure and Conformational Change Probed Using Fourier Transform Infrared Spectroscopy
Raman Spectroscopy on Light Harvesting Complex
EXPLORING STRUCTURE-FUNCTION RELATIONSHIPS IN WHOLE CELLS
Energy Transfer Technologies to Monitor the Dynamics and Signaling Properties of G-protein Coupled Receptors in Living Cells

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