Biophysical Chemistry / Edition 1

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"Biophysical Chemistry is an outstanding book that delivers both fundamental and complex biophysical principles, along with an excellent overview of the current biophysical research areas, in a manner that makes it accessible for mathematically and non-mathematically inclined readers." (Journal of Chemical Biology, February 2009)


This text presents physical chemistry through the use of biological and biochemical topics, examples and applications to biochemistry. It lays out the necessary calculus in a step by step fashion for students who are less mathematically inclined, leading them through fundamental concepts, such as a quantum mechanical description of the hydrogen atom rather than simply stating outcomes. Techniques are presented with an emphasis on learning by analyzing real data.

  • Presents physical chemistry through the use of biological and biochemical topics, examples and applications to biochemistry
  • Lays out the necessary calculus in a step by step fashion for students who are less mathematically inclined
  • Presents techniques with an emphasis on learning by analyzing real data
  • Features qualitative and quantitative problems at the end of each chapter
  • All art available for download online and on CD-ROM
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Editorial Reviews

Doody's Review Service
Reviewer: George C Papageorgiou, Ph. D.(National Center of Scientific Research "Demokritos")
Description: The book introduces the basic concepts of thermodynamics, kinetics, quantum mechanics, spectroscopy, and atomic and molecular structure to enable readers to approach biological themes from a physicochemical viewpoint.
Purpose: The purpose was to provide a textbook for teaching biology from a physical-chemistry viewpoint, a worthy objective that this book achieves.
Audience: The author intends this book for university students, and it is appropriate for advanced undergraduate and graduate university students as well as intellectually alert professionals (university and high school educators, medical doctors, researchers, et al.).
Features: "Importantly, each chapter in the first two parts includes a research direction section that guides readers into frontline themes of broader or global interest in biophysics, biology, and medicine. The four chapters in the third and final part delve into selected areas of biology, such as vision, transport of molecules and ions across biological membranes, cell, tissue, and organism imaging, PET scanning, and Parkinson's disease. This part concludes with a discussion of photosynthesis. "
Assessment: "Biophysics defines a truly a vast area of human knowledge and experience, so the author had to be critically selective, and he was successful. For readers who may want to explore a particular direction further, lists of references at the end of each chapter will provide them guidance. This is strongly recommended as a textbook for advanced undergraduate and graduate students with backgrounds in the physical and biological sciences. It will also prove extremely useful to university and high school educators, medical doctors, and researchers who want to go beyond a surface treatment of biological phenomenology to its roots in physics and chemistry. "
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Product Details

  • ISBN-13: 9781405124362
  • Publisher: Wiley
  • Publication date: 9/16/2008
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 512
  • Product dimensions: 7.70 (w) x 9.80 (h) x 1.10 (d)

Meet the Author

James Allen is a professor at Arizona State University. He has won numerous honors including several study sections with the National Institutes for Health and was selected for Who’s Who Among America’s Teachers.

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Table of Contents


1. Basic Thermodynamic and Biochemical Concepts.

Part 1: Thermodynamics and Kinetics:.

2. First Law of Thermodynamics.

3. Second Law of Thermodynamics.

4. Phase Diagrams, Mixtures, and Chemical Potential.

5. Equilibria and Reactions Involving Protons.

6. Oxidation/Reduction Reactions and Bioenergetics.

7. Kinetics and Enzymes.

8. The Boltzmann Distribution and Statistical Thermodynamics.

Part 2: Quantum Mechanics and Spectroscopy:.

9. Quantum Theory: Introduction and Principles.

10. Particle in a Box and Tunneling.

11. Vibrational Motion and Infrared Spectroscopy.

12. Atomic Structure: Hydrogen Atom and Multi-Electron Atoms.

13. Chemical Bonds and Protein Interactions.

14. Electronic Transitions and Optical Spectroscopy.

15. X-Ray Diffraction and Extended X-Ray Absorption Fine Structure.

16. Magnetic Resonance.

Part 3: Understanding Biological Systems using Physical Chemistry:.

17. Signal Transduction.

18. Membrane Potentials, Transporters, and Channels.

19. Molecular Imaging.

20. Photosynthesis.

References and Further Reading.


Answers to Problems.


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