Biopsy Interpretation of the Prostate / Edition 6

by Jonathan I. Epstein

Overview

Part of the highly regarded Biopsy Interpretation Series, this fully revised volume is your definitive guide to mastering biopsy pathology interpretation for prostate cancer care. Biopsy Interpretation of the Prostate, 6th Edition, provides superbly illustrated guidance from a top expert in the field, guiding you through the best utilization of H&E microscopy as well as the latest immunohistochemical markers in order to deliver accurate, reliable diagnoses. Hundreds of full-color illustrations depict the full range of benign and malignant prostatic entities.
 

• Focuses on practical, need-to-know information regarding the diagnosis and prognosis of prostate cancer obtained on biopsy, addressing both common and unusual issues that arise in day-to-day practice.
• Provides new information on noninvasive lesions (HGPIN and intraductal carcinoma), clinical correlates with biopsy, and practical molecular findings.
• Shows how to critically use adjunctive tests to both diagnose limited prostate cancer and avoid overdiagnosing mimickers of prostate cancer.
• Emphasizes the newest updates in prostate cancer grading so that you can provide the most accurate prognostication in your biopsy reports.
• Features 1800 images online, as well as a 50-question test bank for self-assessment and review.

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Product Details

ISBN-13:	9781975136543
Publisher:	LWW
Publication date:	01/07/2020
Series:	Biopsy Interpretation Series
Edition description:	Sixth
Pages:	436
Product dimensions:	6.10(w) x 9.30(h) x 0.90(d)

Table of Contents

Preface to the First Edition     viii
Preface     x
Clinical Correlates with Biopsy     1
Needle Biopsy Technique     6
Gross Anatomy and Normal Histology     13
Inflammatory Conditions     22
Prostatic Intraepithelial Neoplasia and Its Mimickers     55
Diagnosis of Limited Adenocarcinoma     72
Mimickers of Adenocarcinoma of the Prostate     105
Reporting Cancer: Influence on Prognosis and Treatment     157
Grading of Prostatic Adenocarcinomas     175
Findings of Atypical Glands Suspicious for Cancer     203
Prostatic Duct Adenocarcinoma     218
Neuroendocrine Differentiation in the Benign and Malignant Prostate     228
Mucinous Differentiation in the Benign and Malignant Prostate     238
Benign and Malignant Prostate Following Treatment     246
Urothelial Carcinoma     262
Mesenchymal Tumors and Tumor-like Conditions     275
Miscellaneous Benign and Malignant Lesions     296
Prostatic Urethral Lesions     318
Emerging Biomarkers for the Detection and Management of Prostate Carcinoma     330
Macros     340
Index     346

Editorial Reviews

Reviewer: Anamarija Perry, MD (University of Michigan Medical School)
Description: This is the fourth edition of a book in the Biopsy Interpretation series that comprehensively covers prostate pathology and interpretation of prostate biopsy specimens. This edition is significantly expanded and updated over the third, published in 2002, and some chapters have been extensively modified.
Purpose: It is written as a guide for surgical pathologists interpreting and reporting prostate biopsies. It covers systematically the entire pathology of the prostate with a special emphasis on important differential diagnoses. Use of immunohistochemical techniques in the diagnosis of prostate cancer, along with their limitations and potential pitfalls, is also included.
Audience: This book will be of interest to all pathologists who evaluate biopsy material from the prostate. It will be also useful to pathology residents and fellows. Certain chapters, especially on reporting prostatic cancer and biomarkers for the detection and management of prostate carcinoma, will be useful to all clinicians involved in the treatment of patients with prostate cancer.
Features: The first two chapters deal with clinical correlates with prostate biopsy and biopsy techniques and the third chapter covers gross anatomy and normal histology of the prostate. Inflammatory conditions, prostatic intraepithelial neoplasia, and mimickers of prostatic adenocarcinoma are covered in separate chapters. Chapters on reporting of prostate cancer and grading are also included. Different histologic variants of prostate cancer, as well as urothelial carcinoma, mesenchymal tumors, rare tumors, and prostatic urethral lesions are covered. A separate chapter covers therapy-induced changes in the prostate. The last chapter covers biomarkers for the detection and management of prostate cancer. This edition increases the number of images and all of them are now in color. Throughout the book, greater use is made of tables for the differential diagnosis of prostate cancer and its mimickers. The chapter on prostatic intraepithelial neoplasia and its mimickers is updated to provide new recommendations for follow-up. The chapter on the diagnosis of limited adenocarcinoma of the prostate is totally reworked to provide a methodical approach to the diagnosis of cancer on biopsies using architectural, cytological, and ancillary features. A new expanded section on the use of immmunohistochemistry for the diagnosis of prostate cancer has been added. The chapter on grading of prostatic adenocarcinomas is rewritten to cover the New Consensus on the Updating of Gleason grading system. Recently described entities such as intraductal carcinoma and PIN-like ductal adenocarcinoma are discussed. A chapter on emerging biomarkers for the detection and management of prostate cancer provides readers with the latest array of molecular markers that may be used in the near future as adjuncts to currently established prognostic parameters. The book is well illustrated and the quality of the images is excellent. Numerous tables cover differential diagnosis and immunohistochemical features of different benign and malignant lesions in the prostate. In addition, an interactive web site with an image bank and test bank with multiple choice questions complements the book.
Assessment: This is an extremely helpful book for pathologists and pathologists in training who evaluate prostate biopsies. It should be widely distributed to pathology departments. The entire field of prostate pathology is covered in a concise, yet comprehensive manner. The book is a great quick reference and very helpful tool for the everyday work of a surgical pathologist. Among the strongest features of the book are the numerous tables that deal with differential diagnoses of prostate cancer versus benign conditions. The book is well illustrated with numerous excellent images that complement the text. In the sometimes confusing area of prostate pathology, this book will help you to interpret and report prostate biopsy in a modern, up-to-date, and patient-oriented way.

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