Bioreactors for Tissue Engineering: Principles, Design and Operation / Edition 1

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Overview

For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed.

Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for several tissue types (bone, cartilage, vascular), addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth.

This unique volume is dedicated to the fundamentals and application of bioreactor technology to tissue engineering products. Not only will it appeal to graduate students and experienced researchers in tissue engineering and regenerative medicine, but also to tissue engineers and culture technologists, academic and industrial chemical engineers, biochemical engineers and cell biologists who wish to understand the criteria used to design and develop novel systems for tissue growth in vitro.

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Product Details

  • ISBN-13: 9781402037405
  • Publisher: Springer Netherlands
  • Publication date: 10/18/2005
  • Edition description: 2005
  • Edition number: 1
  • Pages: 376
  • Product dimensions: 9.21 (w) x 6.14 (h) x 0.88 (d)

Table of Contents

1 Bioreactor systems for tissue engineering : a four-dimensional challenge 1
2 Microreactor optimisation for functional tissue engineering 19
3 Taylor-vortex bioreactors for enhanced mass transport 47
4 Packed bed bioreactors 87
5 Design and operation of a radial flow bioreactor for reconstruction of culture tissues 115
6 Cartilage growth in magnetic resonance microscopy-compatible hollow fiber bioreactors 135
7 Mechanical conditioning of cell-seeded constructs for soft tissue repair - are optimisation strategies possible? 165
8 Mechanical bioreactors for bone tissue engineering 193
9 A dynamic straining bioreactor for collagen-based tissue engineering 209
10 Bioreactors for ligament engineering 221
11 Biomechanical considerations for tissue engineered heart valve bioreactors 235
12 Design of vascular graft bioreactors 269
13 Perfusion bioreactors for cardiovascular tissue engineering 285
14 Haematopoietic culture systems 309
15 Monitoring the performance of tissue engineering bioractors using magnetic resonance imaging and spectroscopy 335
16 Cryopreservation of hepatocytes for bioartificial liver devices 353
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