Biosafety Level 4 (BSL4) - Virus research at the highest level of biosafety and biosecurity

by Sandra Diederich (Editor)

Overview

Advances in Virus Research, Volume 122 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including HERVs in cancer stem cells, Nomenclature for vertical, Modelling of vertically transmitted viruses, Vertical transmission of tomato viruses, and more.

Product Details

ISBN-13:	9780443344916
Publisher:	Elsevier Science
Publication date:	08/01/2025
Series:	Advances in Virus Research , #122
Pages:	258
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

Dr. Benhur Lee is a Professor of Microbiology at the Icahn School of Medicine at Mount Sinai (ISMMS). Prof. Lee also holds the Ward-Coleman Chair in Microbiology. He obtained his M.D. from Yale University School of Medicine (1995) and completed his clinical as well as post-doctoral training at the University of Pennsylvania (1995-2001). Dr. Lee is board-certified in Clinical Pathology. Prior to 2014, he was a Professor in the Dept of Microbiology, Immunology & Molecular Genetics, and the Dept of Pathology & Laboratory Medicine at the David Geffen School of Medicine at UCLA (2001-2013). Dr. Lee is a scientific advisor to the Standards Working Group (SWG) of the California Institute of Regenerative Medicine (CIRM, 2014-present), and was an appointed member of the NIH Director’s Recombinant DNA Advisory Committee (RAC), more recently reconstituted as the Novel and Exceptional Technology and Research Advisory Committee (NExTRAC) (2016-2022). He is an elected fellow of the American Academy of Microbiology and Councilor for Medical Virology (American Society for Virology, 2022-2025). He is also a paramyxovirus study group member of the International Committee on the Taxonomy of Viruses (ICTV) and served on the WHO R&D Blueprint pathogen prioritization scientific review group for paramyxovirus (2023-2024). Dr. Lee has a special interest in emerging RNA viruses, with a focus on molecular viral-host interactions. His lab has made significant contributions to the study of paramyxovirus entry, budding and pathogenic mechanisms. His guiding principle is to translate insights gained from basic studies on host-pathogen interactions into anti-viral therapeutics. Dr. Lee has published over 200 peer-reviewed articles and reviews, and serves on multiple editorial boards. His work has been cited more than 15,000 times and he has a h-index of 68 as of 2024. His research has been supported by the National Institutes of Health (USA), the National Science Foundation (USA), the Department of Defense (USA) as well as private and public research foundations. Dr. Lee has trained more than a dozen post-doctoral fellows, 18 graduate students, and has served on more than 60 PhD dissertation committees between UCLA and Mount Sinai.

Professor Martin Beer works at the Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Germany

Table of Contents

1. Mucosal Sudan virus infection results in a lethal disease in ferrets with previous Lloviu virus infection not providing cross-protection
Andrea Marzi
2. Transcriptional signatures of Ebola and Marburg virus infection in a Bat-Immune-System (BIS) mouse model
Dániel Cadar, Balázs Horváth, Melanie Rissman, Heike Baum, Alexandra Bialonski, Michelle Heung, Philip Lawrence, Anne Balkema-Buschmann, Estefanía Rodríguez and Beatriz Escudero-Pérez
3. More similar than different: a comparison of human and veterinary BSL4 containment facilities”
Michael Eschbaumer
4. Molecular expressions in tissues and blood following Reston and Bundibugyo virus infection in swine
Brad Pickering, Ji-Young Kim, Jodi L. McGill, Charles Lewis, Mathieu Pinette, Harry Dawson and Oliver Lung
5. Relevance of studying virus – natural reservoir interactions: SNV in deer mice and LASV in Mastomys natalensis
Dave Safronetz, Levi Klassen and Jeremie Prevost

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From the Publisher

Edited by one of the best scientists in the field, this series presents the latest updates in the field of virus research