Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs / Edition 1

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Overview

Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. The new edition also provides an update on new proteins and genetic medicines, the translational and integrated sciences that continue to fuel the innovations in medicine, as well as the new areas of therapeutic development including cancer vaccines, stem cell therapeutics, and cell-based therapies.

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Editorial Reviews

From the Publisher
“Overall, this book provides a valuable resource that can be utilized as a quick look-up guide and, more importantly, as an educational tool that can be used in strategic planning. The presentation style provides comprehensive information amenable to a diverse audience.” (Clinical Infectious Diseases, 30 October 2014)
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Product Details

  • ISBN-13: 9780471206903
  • Publisher: Wiley
  • Publication date: 8/1/2003
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 576
  • Product dimensions: 7.13 (w) x 10.14 (h) x 1.25 (d)

Meet the Author

Active individual and professional traders.

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Table of Contents

Foreword
Preface
Organization of the Book
Contributors
Pt. I Transforming Proteins and Genes Into Therapeutics 1
1 Introduction to Biopharmaceuticals 3
2 Comparative Drug Development of Proteins and Genes versus Small Molecules 11
3 Biotechnology Industry Perspective on Drug Development 21
4 Biopharmaceutical Technologies and Processes in Drug Development 35
5 Pharmacology, Toxicology, Therapeutic Dosage Formulations, and Clinical Response 97
Pt. II Therapeutics Based on Biotechnology 125
6 Hematopoietic Growth Factors and Coagulation Factors 127
7 Interferons and Cytokines for Anti-infective and Cancer Therapy 161
8 Hormones 209
9 Enzymes 245
10 Antibodies and Derivatives 271
11 Vaccines 313
12 Other Products: Monographs 331
Pt. III Future Directions 337
13 Advanced Drug Delivery 339
14 Individualization of Drug Regimens: Integration of Pharmacokinetic and Pharmacogenetic Principles in Drug Therapy 381
15 Gene and Cell Therapy 401
16 Integration of Discovery and Development: The Role of Genomics and Proteomics 427
App. I Dosage Form, Pharmacokinetics, and Disposition Data 445
App. II Molecular Characteristic and Therapeutic Use 467
App. III Nomenclature of Biotechnology Products 495
App. IV Synonyms of Trade, Common, and Scientific Names 499
App. V Other Information Tables 527
Index 539
Monographs Index 555
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  • Anonymous

    Posted August 5, 2003

    Useful Book

    '...faculty that teach in the pharmaceutics curriculum will find the Ho and Gibaldi text of great value as course content is revised and new areas are added and expanded. The book provides important linkages between the science and therapeutics of biotechnology products that faculty will find useful in integrating the subject matter in health sciences and graduate program curricula.' --Stuart Feldman, Ph.D., Biomedical and Health Sciences Institute and Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, Georgia

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