Bone Resorption / Edition 1

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"Bone Resorption, the second volume in the series Topics in Bone Biology, deals with the osteoclast, the bone-resorbing cell, its origins, its enzymes, the regulation of osteoclast activity, and structural aspects of bone resorption." The reviews in the book are essential reading for clinicians, researchers and students in a variety of fields: skeletal biology and orthopedics, nutrition, rheumatology, endocrinology, nephrology, oncology, dentistry, nursing, and chiropractic medicine.
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Editorial Reviews

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"Volume 2 in the series Bone Biology and written by US experts, it reviews in 9 chapters the biology, physiology and physiopathology of the osteoclast. It also describes the new drugs which inhibit bone resorption. A very complete, well referenced text, of interest to all who research or treat bone diseases, including pediatric endocrinologists." (Zvi Laron, Pediatric Endocrinology Reviews, Vol. 3 (2), 2005)

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Product Details

  • ISBN-13: 9781852338121
  • Publisher: Springer London
  • Publication date: 7/1/2005
  • Series: Topics in Bone Biology, #2
  • Edition description: 2005
  • Edition number: 1
  • Pages: 190
  • Product dimensions: 0.50 (w) x 7.00 (h) x 10.00 (d)

Table of Contents

1 Osteoclast : origin and differentiation 1
2 Osteolytic enzymes of osteoclasts 24
3 Regulation of osteoclast activity 34
4 Structural aspects of bone resorption 58
5 Inflammatory cytokines 67
6 Genetics and mutations affecting osteoclast development and function 91
7 Clinical disorders associated with alterations in bone resorption 108
8 Pharmaceuticals for bone disease targeting the osteoclast 128
9 Skeletal complications of malignancy : central role for the osteoclast 151
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