Bioinformatics and Functional Genomics / Edition 2

Bioinformatics and Functional Genomics / Edition 2

by Jonathan Pevsner
     
 

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ISBN-10: 0470085851

ISBN-13: 9780470085851

Pub. Date: 05/04/2009

Publisher: Wiley

The bestselling introduction to bioinformatics and functional genomics—now in an updated edition

Widely received in its previous edition, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded Second Edition, it continues to be the go-to source

Overview

The bestselling introduction to bioinformatics and functional genomics—now in an updated edition

Widely received in its previous edition, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded Second Edition, it continues to be the go-to source for students and professionals involved in biomedical research.

This edition provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include:

  • Several fundamentally important proteins, such as globins, histones, insulin, and albumins, are included to better show how to apply bioinformatics tools to basic biological questions
  • A completely updated companion Web site, which will be updated as new information becomes available
  • Descriptions of genome sequencing projects spanning the tree of life
  • A stronger focus on how bioinformatics tools are used to understand human disease

The book is complemented by lavish illustrations and more than 500 figures and tables—fifty of which are entirely new to this edition. Each chapter includes a Problem Set, Pitfalls, Boxes explaining key techniques and mathematics/statistics principles, Summary, Recommended Reading, and a list of freely available software. Readers may visit a related Web page for supplemental information at www.wiley.com/go/pevsnerbioinformatics.

Bioinformatics and Functional Genomics, Second Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.

Product Details

ISBN-13:
9780470085851
Publisher:
Wiley
Publication date:
05/04/2009
Edition description:
Older Edition
Pages:
992
Product dimensions:
8.40(w) x 10.80(h) x 1.40(d)

Table of Contents

PART 1. ANALYZING DNA, RNA, AND PROTEIN SEQUENCES IN DATABASES
Chapter 1. Introduction
Chapter 2. Access to Sequence and Literature Databases
Chapter 3. Pairwise Sequence Alignment
Chapter 4. Basic Local Alignmnet Search Tool (BLAST)
Chapter 5. Advanced BLAST Searching
PART 2. GENOME-WIDE ANALYSIS OF RNA AND PROTEIN
Chapter 6. Genome-wide Analysis of Gene Expression
Chapter 7. Gene Expression: Microarrays
Chapter 8. Protein Analysis and Proteomics
Chapter 9. Protein Structure
Chapter 10. Multiple Sequence Alignment
Chapter 11. Molecular Phylogeny
PART 3. GENOME ANALYSIS
Chapter 12. Completed Genomes and the Tree of Life
Chapter 13. Completed Genomes: Viruses
Cchapter 14. Completed Genomes: Bacteria and Archaea
Chapter 15. Eukaryotic Genomes: Fungi
Chapter 16. Eukaryotic Genomes: From Parasites to Primates
Chapter 17. The Human Genome
Chapter 18. Human Disease
Chapter 19. Conclusions
Appendix 1. GCG for Protein and DNA Analysis
Glossary
Index

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