Molecular Pathology: The Molecular Basis of Human Disease

Molecular Pathology: The Molecular Basis of Human Disease

by William B. Coleman
     
 

"The editors of Molecular Pathology have produced a comprehensive compendium of the state-of-the-art in molecular pathogenesis, an impressive accomplishment given the diverse cells and organ systems involved in human disease. An established cadre of experts has contributed to this first, well-designed edition. As a result, essential topics ranging from cell

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Overview

"The editors of Molecular Pathology have produced a comprehensive compendium of the state-of-the-art in molecular pathogenesis, an impressive accomplishment given the diverse cells and organ systems involved in human disease. An established cadre of experts has contributed to this first, well-designed edition. As a result, essential topics ranging from cell injury/death, the molecular basis of cardiovascular diseases and disorders of the nervous system, and modern molecular diagnostics are amply addressed. In a rapidly emerging discipline, it is challenging to capture the details that define the field. Molecular Pathology has accomplished this goal in an outstanding manner and will serve as an excellent resource for those already established in clinical care and biomedical research, for those who seek to maintain competency in molecular pathology, as well as for all students involved in interdisciplinary studies related to human disease or modern clinical investigations."

Linda M. McManus, PhD, Professor, University of Texas Health Science Center at San Antonio

"The focus of Molecular Pathology is genetic and molecular but it has been written toenhance thework of an active pathologist, clearly describing the basics as well as providing ample sampling of the molecular complexities of disease. Gladly the editors did not assemble an exhaustive compendium of facts and details that would inevitably become obsolete in short order.Instead, the contributorsconcentrated on clarity of explanationsupported by selected examples so that the reader may grasp the fundamentals better.In fact, this may be one medical textbook thatcan be read cover-to-cover without being lost in details. The figures are clear, helpful, and plentiful which is important when dealing with so many complex technologies and concepts. I highly recommend this book."

Edison T. Liu, M.D, Executive Director, Genome Institute of Singapore

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Product Details

ISBN-13:
9780123744197
Publisher:
Elsevier Science
Publication date:
03/16/2009
Edition description:
New Edition
Pages:
664
Product dimensions:
8.60(w) x 11.00(h) x 1.40(d)

Table of Contents

PART I: Essential Pathology - Mechanisms of Disease
Molecular Mechanisms of Cell Death
Acute and Chronic Inflammation
Infection and Host Response
Neoplasia

PART II: Concepts in Molecular Biology and Genetics
Basic Concepts in Human Molecular Genetics
The Human Genome: Implications for the Understanding of Human Disease
The Human Transcriptome: Implications for the Understanding of Human Disease
The Human Epigenome: Implications for the Understanding of Human Disease
The Human Proteome: Implications for the Understanding of Human Disease
Integrative Systems Biology: Implications for the Understanding of Human Disease

PART III:Principles and Practice of Molecular Pathology
Pathology: The Clinical Description of Human Disease
Molecular Pathogenesis: The Biological Basis of Human Disease
Integration of Molecular and Cellular Pathogenesis

PART IV: Molecular Pathology of Human Disease
Molecular Basis of Cardiovascular Disease
Molecular Basis of Hemostatic and Thrombotic Diseases
Molecular Basis of Lymphoid and Myeloid Diseases
Molecular Basis of Diseases of Immunity
Molecular Basis of Pulmonary Disease
Molecular Basis of Diseases of the Gastrointestinal Tract
Molecular Basis of Liver Disease
Molecular Basis of Diseases of the Exocrine Pancreas
Molecular Basis of Diseases of the Endocrine System
Molecular Basis of Gynecologic Diseases
Molecular Basis of Prostate Disease
Molecular Basis of Breast Disease
Molecular Basis of Skin Disease
Molecular Basis of Diseases of the Nervous System

PART V: Practice of Molecular Medicine
Molecular Diagnosis of Human Disease
Molecular Assessment of Human Disease in the Clinical Laboratory
Pharmacogenomics and Personalized Medicine in the Treatment of Human Disease

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