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Molecular Biology of the Gene / Edition 6
     

Molecular Biology of the Gene / Edition 6

by James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine
 

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ISBN-10: 0321827260

ISBN-13: 9780321827265

Pub. Date: 02/13/2012

Publisher: Benjamin Cummings

This sixth edition of James D. Watson's classic textbook Molecular Biology of the Gene has been thoroughly revised and updated. Accessible to anyone interested in molecular biology and genetics, the book provides a historical basis for the field, concise descriptions of fundamental chemical concepts, a comprehensive survey of genome maintenance and expression, and a

Overview

This sixth edition of James D. Watson's classic textbook Molecular Biology of the Gene has been thoroughly revised and updated. Accessible to anyone interested in molecular biology and genetics, the book provides a historical basis for the field, concise descriptions of fundamental chemical concepts, a comprehensive survey of genome maintenance and expression, and a discussion of standard techniques and model organisms commonly used in molecular biology studies. It includes all new chapters on the regulatory RNAs and genomics and systems biology. The book has an accompanying Web site (aw-bc.com), which contains interactive tutorials, animations, and critical-thinking exercises designed to help students explore and visualize complex concepts. This book is co-published with Benjamin Cummings. Requests for examination copies for teextbook adoptions should be sent to Benjamin Cummings at aw-bc.com

Product Details

ISBN-13:
9780321827265
Publisher:
Benjamin Cummings
Publication date:
02/13/2012
Pages:
880
Product dimensions:
8.40(w) x 10.90(h) x 1.20(d)

Table of Contents

Part 1Chemistry and Genetics1
1The Mendelian View of the World5
2Nucleic Acids Convey Genetic Information19
3The Importance of Weak Chemical Interactions41
4The Importance of High-Energy Bonds55
5Weak and Strong Bonds Determine Macromolecular Structure69
Part 2Maintenance of the Genome93
6The Structures of DNA and RNA97
7Chromosomes, Chromatin, and the Nucleosome129
8The Replication of DNA181
9The Mutability and Repair of DNA235
10Homologous Recombination at the Molecular Level259
11Site-Specific Recombination and Transposition of DNA293
Part 3Expression of the Genome343
12Mechanisms of Transcription347
13RNA Splicing379
14Translation411
15The Genetic Code461
Part 4Regulation479
16Gene Regulation in Prokaryotes483
17Gene Regulation in Eukaryotes529
18Gene Regulation during Development575
19Comparative Genomics and the Evolution of Diversity613
Part 5Methods643
20Techniques of Molecular Biology647
21Model Organisms681
Index713

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