Stem Cells: Scientific Facts and Fiction

Stem Cells: Scientific Facts and Fiction

by Christine Mummery, Anja van de Stolpe, Bernard Roelen, Hans Clevers
     
 

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The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem

Overview

The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells.

In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies.



  • Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy
  • Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice
  • Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

Editorial Reviews

From the Publisher
"... an impressive encyclopedia of modern biotechnology that presents complex material in short, easy-to-grasp chapters...a solid, informative effort...Summing Up: Highly recommended."—CHOICE

"...Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy…Includes extensive coverage of adult and embryonic stem cells..."—Anticancer Research, February 2015

"... a valuable resource for both biologists and nonbiologists interested in the history and the state-of-the-art developments in the field of stem cell research and its applications. The writing style is quite engaging, and numerous illustrations help to explain the concepts. 3 Stars - Score: 85"—Doody's.com, Nov 14 2014

Stem Cells, 1st Edition - Winner of two British Medical Association 2011 awards: BMA Board of Science Award for the Public Understanding of Science and First Prize in the category of Basic and Clinical Sciences

Doody's Review Service
Reviewer: Joanna Goral, PhD (Midwestern University)
Description: This is a comprehensive and accessible overview of the history and recent developments in academic and clinical stem cell research. With the many advances and new developments in this dynamic field, this update of the 2010 edition is fully justified.
Purpose: The book extensively reviews the scientific facts about stem cells and their remarkable promise in developing new treatments for cancer and chronic diseases of old age, in drug discovery, and their application in biotechnology and tissue engineering. The authors also address ethical issues that surround the use of embryonic stem cells and warn about fraudulent stem cell practices that continue to increase.
Audience: The intended audience is diverse, including students and scientists, as well as nonbiologists, who are interested in this field.
Features: Among the many publications in the field of stem cell biology, this book is truly important because of its accessibility to a general audience. The opening chapters introduce the basic biology of the cell, describe embryonic development, and define and characterize different types of stem cells. Subsequent chapters are devoted to applications of stem cells in regenerative medicine, the significance of stem cells in cancer development and treatment, new developments in human disease models, personalized medicine, and drug discovery. Applications of stem cells in veterinary medicine are also discussed. The field of stem cell research offers great promise, but is mired in controversy and the authors present all sides of the debate. They also devote an entire chapter to "stem cell tourism," a practice among patients who pay large sums of money for often unproven stem cell therapies.
Assessment: This is a valuable resource for both biologists and nonbiologists interested in the history and the state-of-the-art developments in the field of stem cell research and its applications. The writing style is quite engaging, and numerous illustrations help to explain the concepts. Many historical, informative, and anecdotal vignettes enliven the book.

Product Details

ISBN-13:
9780124115675
Publisher:
Elsevier Science
Publication date:
05/23/2014
Sold by:
Barnes & Noble
Format:
NOOK Book
Pages:
448
File size:
9 MB

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