Brain Aging: Models, Methods & Mechanisms

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Bringing together current theories on brain aging and the experimental methods testing and advancing these theories, Brain Aging investigates fundamental age-related changes in the brain rather than age-related neurodegeneration. While offering a breadth of coverage that will satisfy casual observers of the field, it provides significant depth to be of value to both researchers of the aging brain, as well as clinicians treating elderly patients. Written by pioneering researchers, it reviews critical studies of brain aging in animal models and new insights from human brain imaging. It also explores the distinct methodological challenges inherent in investigating the aging nervous system.

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Product Details

  • ISBN-13: 9780849338182
  • Publisher: Taylor & Francis
  • Publication date: 11/15/2006
  • Series: Frontiers in Neuroscience Series
  • Pages: 408
  • Product dimensions: 6.20 (w) x 9.30 (h) x 1.10 (d)

Table of Contents

Assessing Cognitive Aging
Changes in Cognitive Function in Human Aging, E. L. Glisky
Successful vs. Unsuccessful Aging in Rhesus Monkeys, M.B. Moss, T. L. Moore, S.P. Schettler, R. Killiany, and D. Rosene
Neuropsychology of Cognitive Aging in Rodents, J. S. Rodefer and M. G. Baxter
Quantifying Aging-Related Changes in the Brain
Design-Based Stereology in Brain Aging Research, C. Schmitz and P.R. Hof
The Effects of Normal Aging on Nerve Fibers and Neuroglia in the Central Nervous System, A. Peters
Neurogenesis in the Adult and Aging Brain, D.R. Riddle and R.J. Lichtenwalner
Expression Profile Analysis of Brain Aging, S.D. Ginsberg, Ph.D.
Assessing Functional Changes in the Aging Nervous System
Subtle Alterations in Glutamatergic Synapses Underlie the Aging-Related Declines in Hippocampal Functions, L. Shi, M. Adams, and J. Brunso-Bechtold
Assessment of Second Messenger Function in the Hippocampus of Aged Rats with Cognitive Impairment, M.M. Nicolle, H.Y. Zhang, and J. L. Bizon
Neurophysiology of Old Neurons and Synapses, A. Kumar and T. C. Foster
Imaging Cognition in the Aging Human Brain, T. Hedden
Mechanisms Contributing to Brain Aging
Regulation of Cerebrovascular Aging, W.E. Sonntag, D.M. Eckman, J.Ingraham, and D.R. Riddle
Stress and Glucocorticoid Contributions to Normal and Pathological Aging, K.A. Goosens and R.M. Sapolsky
Altered Calcium Homeostasis in Old Neurons, E.C. Toescu
Oxidative Stress and the Aging Brain: from Theory to Prevention, C.Gemma, Ph.D., J. Vila, A. Bachstetter, and P. C. Bickford, Ph.D.

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