Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics / Edition 1

Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics / Edition 1

by Anne M. Bowcock
     
 

ISBN-10: 161737072X

ISBN-13: 9781617370724

Pub. Date: 11/09/2010

Publisher: Springer-Verlag New York, LLC

In Breast Cancer: Molecualr Genetics, Pathogenesis, and Therapeutics, Anne Bowcock has brought together many leading authorities to create today's leading state-of-the-art summary of breast cancer research and treatment. The book's many distinguished contributors illuminate the biology and genetics of breast cancer, including what is known about the hereditary

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Overview

In Breast Cancer: Molecualr Genetics, Pathogenesis, and Therapeutics, Anne Bowcock has brought together many leading authorities to create today's leading state-of-the-art summary of breast cancer research and treatment. The book's many distinguished contributors illuminate the biology and genetics of breast cancer, including what is known about the hereditary breast cancer genes, BRCA1 and 2, the cutting-edge cytogenic approaches, and the biology of breast cancer metastasis. In addition, the authors describe current and future methods of breast cancer treatment in depth, and discuss environment and diet as risk factors for the disease.

Constituting an excellent reference and resource for all clinical and experimental oncologists as well as those genetic counselors and nurses who need to understand the latest developments in breast cancer biology, risk, and treatment, Breast Cancer: Molecualr Genetics, Pathogenesis, and Therapeutics will broaden their knowledge of the disease and permit them to focus on the critical questions that still need to be answered.

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Product Details

ISBN-13:
9781617370724
Publisher:
Springer-Verlag New York, LLC
Publication date:
11/09/2010
Series:
Contemporary Cancer Research Series
Edition description:
Softcover reprint of hardcover 1st ed. 1999
Pages:
582
Product dimensions:
7.00(w) x 10.00(h) x 1.24(d)

Related Subjects

Table of Contents

Part I. Etiology: Genetic Changes Associated with Breast Cancer. The Estrogen Receptor and Breast Cancer, R. K. Hansen and S. A. W. Fuqua. Epidermal Growth Factor-Related Peptides and Their Cognate Receptors in Breast Cancer, Isabel Martinez-Lacaci, Caterina Bianco, Marta De Santis, and David S. Salomon. The Role of Fibroblast Growth Factors in Breast Cancer Pathogenesis and Progression, Francis G. Kern. Transforming Growth Factor-ß and Breast Cancer, Katri M. Koli and Carlos L. Arteaga. The Insulin-Like Growth Factor Network and Breast Cancer, Matthew J. Ellis. Molecular Alterations in Breast Cancer, Ivan Bergstein. Apoptosis and the Development of Breast Cancer, Priscilla A. Furth. WNT Genes and Breast Cancer, Ivan Bergstein and Anthony M. C. Brown. Hereditary Breast Cancer Genes, Lynda B. Bennett, Joel D. Taurog, and Anne M. Bowcock. Biological Functions of the BRCA1 and BRCA2 Proteins, Helen K. Chew, Andrew A. Farmer, and Wen-Hwa Lee. Psychosocial Issues in BRCA1/2 Testing, Caryn Lerman and Beth N. Peshkin. Part II. Biology of Tumor Progression: Breast Cancer Metastasis. Nm23, Breast Differentiation, and Cancer Metastasis, Patricia S. Steeg, Melanie T. Hartsough, and Susan e. Clare. Role of Integrins in the Development and Malignancy of the Breast, Edward C. Rosfjord and Robert B. Dickson. Matrix Metalloproteinases in the Pathogenesis of Breast Cancer, John R. MacDougall and Lynn M. Matrisian. The Urokinase Plasminogen Activation System in Breast Cancer, Anders N. Pedersen, Claus Holst-Hansen, Thomas L. Frandsen, Boye Schnack Nielsen, Ross W. Stephens, and Nils Brünner. Angiogenesis in Breast Cancer: Role in Biology, Tumor Progression, and Prognosis, Giampietro Gasparini. Part III. Therapeutics and Diagnostics: Diagnosis. Cytogenetic Approaches to Breast Cancer, Sverre Heim, Manuel R. Teixeira, and Nikos Pandis. Current and Future Directions in Surgical and Chemotherapeutic Approaches to Breast Cancer Treatment, George N. Peters. Breast Cancer Therapy Using Monoclonal Antibodies Against Epidermal Growth Factor Receptor and HER-2, Zhen Fan and John Mendelsohn. Towards the Therapeutic Targeting of Matrix Metalloproteinases in Breast Cancer, Erik W. Thompson and George W. Sledge, Jr. MUC1 Mucin as a Tumor Antigen in Breast Cancer, Pawel Ciborowski, Elisabeth M. Hiltbold, Simon M. Barratt-Boyes, and Olivera J. Finn. Aromatase Inhibitors and the Role of Hormonal Therapy in Breast Cancer, Kendall E. Donaldson Herschler and Angela Brodie. Drug Resistance in Breast Cancer, Devchand Paul and Kenneth H. Cowan. Smoking as a Risk Factor for Breast Cancer, Christine B. Ambrosone and Peter G. Shields. The Estrogenicity of Selected Nutrients, Phyhemicals, Pesticides, and Pollutants: Their Potential Roles in Breast Cancer, Leena Hilakivi-Clarke, Bruce Trock, and Robert Clarke. Index.

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