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Upper Saddle River, NJ 2000 Hardcover 9th Edition New Condition New book. Multiple copies available this title. Quantity Available: 2. Category: Science & Technology; Biology; ... Biology; ISBN: 0130819220. ISBN/EAN: 9780130819222. Inventory No: ABE323076416. Read more Show Less

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Over the past 30 years eight editions of Biology of Microorganisms have introduced the field of microbiology to hundreds of thousands of students.As we enter a new millennium, this ninth edition of Brock Biology of Microorganisms promises to be a classic among microbiology textbooks with its modern treatment of microbiology firmly rooted in fundamental principles.

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Editorial Reviews

<:st> New edition of a standard text cited in . Introducing the basics of the science of microbiology and its applications, this lavishly illustrated text provides up-to-date coverage of technology and discoveries. Madigan, Martinko, and Parker, all professors of microbiology at Southern Illinois University, Carbondale, carry on Brock's work in their updated coverage of cell biology, nutrition and metabolism, viruses, metabolic diversity, microbial growth control, epidemiology and public health microbiology. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9780130819222
  • Publisher: Pearson Education
  • Publication date: 7/22/1999
  • Edition description: Older Edition
  • Edition number: 9
  • Pages: 1046
  • Product dimensions: 8.56 (w) x 11.20 (h) x 1.46 (d)

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As we enter the new millennium the rapid pace of basic research and the enormous possibilities for applications have thrust the field of microbiology into the forefront of the biological sciences. Through the years the science of microbiology has kept its roots firmly planted in fundamental principles. But now with the explosion of new molecular methods for both field and laboratory studies microbiologists can ask questions and do experiments that they could only dream of years ago. Indeed, as one notable microbiologist put it recently, the science of microbiology is "on a roll." It is during this exciting time that we present to students and instructors of microbiology a snapshot of microbiology today in the form of the ninth edition of Brock Biology of Microorganisms (BBOM).

What's New in Organization?

In the 30 years since the first edition of this book, originally titled Biology of Microorganisms, was published, many things have changed in the field of microbiology. The new edition of BBOM has also seen many changes—some minor, some not so minor—from that of the previous edition. In terms of chapter organization, the ninth edition follows along the lines of the eighth with two exceptions: (1) The chapter on "Microbial Evolution and Systematics" has been moved forward to Chapter 12 to set the stage for later chapters on microbial diversity, metabolic diversity, and ecology. With this move, every chapter in the book that deals with organisms and their activities in nature (including medical microbiology) can be seen, as it should be, within a phylogenetic context. And (2), the chapter entitled"Microbial Growth Control" has been moved back to Chapter 18 in this edition to immediately precede the medical/ immunology block of chapters where it fits better as an introduction to this material.

Because medical microbiology is such an important area of our science, the disease chapter has been restructured and split into two chapters. Chapter 23 is now entitled "Person-to-Person Microbial Diseases" and exclusively covers microbial diseases transmitted in this fashion. Here one will find up-to-the-minute coverage of airborne and sexually transmitted pathogens and the diseases they cause. In Chapter 24, entitled "Animal-Transmitted, Vectorborne, and Common-Source Microbial Diseases," one finds coverage of important diseases transmitted by insects or animals such as malaria, Lyme, hantavirus and rabies, and diseases caused by a common vehicle such as foodborne and waterborne diseases. Those instructors who structure their introductory courses around a theme of medical microbiology will now find more than enough coverage of diseases and the disease process in the ninth edition.

Finally, it should also be mentioned that the new organization in BBOM 9/e conforms very closely to the recommendations of the Education Division of the American Society for Microbiology (ASM) for teaching introductory microbiology courses. This includes the content outline of the new ASM telecourse in microbiology, whose 12-part series produced by Oregon Public Broadcasting and funded by the Annenberg Corporation closely mirrors the organization of material in the ninth edition.

What's New in Content?

What isn't new? Every chapter in this book has seen revision, in some cases, very extensive revision. The authors' goal in producing this new edition was to maintain the breadth and depth of coverage that users have come to expect from this book while at the same time keeping things within bounds, both in terms of what students should be expected to master in one semester, and the overall length of an "introductory" textbook. As for previous editions of this book, the ninth has tried to strike a balance between concepts and details such that the beginning student is not overwhelmed while the more experienced student can still use the book as a general resource.

A very important point for instructors to note is the numbered head system used in this book. As for all eight previous editions, BBOM 9/e is constructed in a modular fashion, using numbered heads to group off major topics within each chapter. Instructors should take advantage of this system by assigning to their students as much or as little (depending on the depth and breadth desired) of the material of a given chapter as necessary. Instructors know that most textbooks can not (and should not) be covered in a single semester course, and BBOM 9/e is no exception. While some chapters of this book should be covered in their entirety in the introductory course, others need only be sampled. The numbered head system makes sampling convenient for instructors and at the same time partitions concepts into more digestible portions for students.

Highlights of the revision include: (1) a more streamlined chapter on cell chemistry (now entitled "Macromolecules") to put the focus on the structure of the cells' major molecules; (2) a major new section on prokaryotic genomics (Chapter 9) to reflect the great excitement and advances occurring in this area today; (3) a major reorganization of the material on prokaryotes (Chapters 13 and 14) along phylogenetic lines to better integrate the evolutionary material in Chapter 12 with the properties of the organisms themselves; (4) extensive coverage of the exciting areas of phylogenetic probes and other fluorescent probes and their use in clinical medicine and microbial ecology (Chapters 16 and 21); (5) an expanded treatment of eukaryotic microorganisms and eukaryotic cell structure (Chapter 17); (6) a heavily reorganized immunology chapter which, following the pattern of the successful "nucleic acids" box in Chapter 6, separates out the molecular details of immunology into a box ("Molecular Biology of the Immune Response") for those instructors that wish to cover the field at the molecular level, while retaining the basic concepts of immunology in the text for those who wish to take a more practical approach to teaching this important area; and (7) an exciting description of the recent emergence of hantavirus pulmonary syndrome (in the new Chapter 24).

In summary, long-time users of this book will find a number of old friends between the covers and will meet a number of new ones as they go along. New users of this book will likely find it to be a refreshing, modern approach to teaching the science of microbiology. Either way, the book itself, coupled with the helpful pedagogical and instructional aids that make up the complete package (see below), should make the ninth edition of BBOM the most "teachable" for the instructor and the most useful to the student, of them all.

Pedagogical Aids

Previous users of this text will quickly notice the entirely new art program in BBOM 9/e. Every piece of art has been re-done, with special care to introduce more three dimensionality where pedagogically useful, and with a better eye for color usage. As before, color is a learning tool in BBOM 9/e and instructors will find that students quickly grasp the significance of color for reinforcing important concepts.

High quality photos and photomicrographs have been a mainstay of Biology of Microorganisms since the first edition appeared in 1970. BBOM 9/e is no exception and contains over 75 new color and black and white photos, most of which, like in previous editions, were supplied by top researchers in the field. Indeed, the combination of a more pleasing art style and superb photos should be well received by today's "visual" generation of students.

As has become a tradition with this book, BBOM 9/e incorporates several study aids into the body of each chapter. Concept links (signaled by the blue "chain link" icon) are the ties between what has just been read and related material found elsewhere in the book; Concept Checks (found at the end of each numbered head) are a brief overview of the previous material followed by several short questions designed to ensure understanding of critical concepts; and the Working Glossary (that begins each chapter) is a dictionary of the essential terms to be encountered therein. With regular use of these study aids students will (1) know where to go within the book to read more about a particular topic; (2) instantly know whether they have mastered a given concept; and (3) have a fingertip reference to the key terminology. In addition to these study aids built into each chapter, BBOM 9/e contains an extensive list of end of chapter study questions designed to both recall important concepts and apply them to solving problems.

This new edition of Brock Biology of Microorganisms comes complete with a companion Website ( On this site you will find supplementary materials for each chapter, an advanced readings list, and a new learning aid introduced with the ninth edition, the "Testing Center." Instructors are well aware that students nowadays like to prepare for upcoming examinations by taking "practice exams." In the BBOM 9/e Testing Center students can do this by taking a "Virtual Exam" for each unit of material, testing their preparedness with thousands of on-line questions designed to help them succeed. The questions themselves have been taken from authentic examinations given in introductory microbiology courses taught at universities throughout the United States that use BBOM as their textbook resource. The instant feedback available on these exams will allow students to assess just how ready they are for exam day in their own classes.


A number of supplements for instructor use accompany the ninth edition. A set of 275 full color transparencies, far more than is available with any other textbook of microbiology, accompany every adoption. Although classroom instruction is going more and more toward computer-generated presentation, the transparency is still the visual aid workhorse in many courses in microbiology; in recognition of this, the publishers are pleased to include 25 more in this edition than its predecessor. But for those instructors whose classrooms are wired for the use of laptop computers, we offer a CD-ROM containing virtually all of the art, photos, and tables from BBOM 9/e. This CD, driven by a new version of the Prentice Hall "Presentation Manager" software system, gives instructors instant access to almost any visual aid in the book and allows them to be organized to fit an instructor's particular needs.

Students were very receptive to the free Website that accompanied the eighth edition of BBOM. Based on their comments and other reviews, we have revised the Website to be even more relevant and helpful. Along with the "Testing Center" mentioned previously, the quiz section of the Website allows students to take self-graded quizzes to test their knowledge, but the number of questions has been expanded and now contains much of the content formerly in the Study Guide. Finally a new feature called "Advances" encourages students to look ahead to the future in microbiology and to research current events using Weblinks we provide.

Between the book itself, the instructors' supplements, and the enhanced Website, we feel we offer an authoritative yet readable account of microbiology as we know it in the twenty-first century and have made available the means to teach it in a first-class way; indeed, BBOM 9/e is a winning package for both students and instructors alike.


This revision is not a product of just the authors. Many college and university instructors of microbiology gave valuable input through reviews of an earlier draft or particular chapters (or sections within a chapter) in the draft, while others made special efforts to provide color photographs taken directly from their laboratory research. We are extremely grateful for their efforts and list them below. Errors and omissions in the text are, of course, the responsibility of the authors, and we would greatly appreciate receiving comments, suggestions, and corrections.

Charles Abella, University of Girona, Spain
Laurie Achenbach, Southern Illinois University
John H. Andrews, University of Wisconsin
Jeanette A. Baker, Archer Daniels Midland Co.
Linda Barnett, University of East Anglia
Carl E. Bauer, Indiana University
Dennis A. Bazylinski, Iowa State University
Mary Bateson, Montana State University
Carl A. Batt, Cornell University
Sharisa Beek, Southern Illinois University
John A. Breznak, Michigan State University
Cheryl Broadie, Southern Illinois University
Ron Browning, Southern Illinois University
Clare Bunce, Cold Spring Harbor Laboratory
Craig Cary, University of Delaware
Richard W. Castenholz, University of Oregon
Feng Chen, University of Georgia
Thomas Christianson, Southern Illinois University
David Clark, Southern Illinois University
Rita Colwell, National Science Foundation
Morris Cooper, Southern Illinois University
Stephen Cooper, University of Michigan
Christian Jeanthon, Centre National de la Recherche Scientifique, Roscoff, France
Leanne Constantine, Affymetrix GeneChip®
Roy Curtiss III, Washington University
Philip R. Cunningham, Wayne State University
Shiladitya DasSarma, University of Massachusetts
Edward Delong, Monterey Bay Aquarium Research Institute
Ravin Donald, Northern Arizona University
Nicole Eis, University of Regensburg, Germany
Imre Friedmann, Florida State University
Brian J. Ford, Rothay House, Cambridgeshire, England
George M. Garrity, Michigan State University
William C. Ghiorse, Cornell University
Kodzo Gbewonyo, Merck and Co., Inc.
John Haddock, Southern Illinois University
Mary Hall, Southern Illinois University
Gary Heil, University of Iowa
Hans Hippe, Deutsche Sammlung von Mikroorganismen and Zellkulturen, Braunschweig, Germany
Robert E. Hodson, University of Georgia
David A. Hopwood, John Innes Centre, Norwich, England
Johannes Imhoff, Universität Kiel, Germany
Edward E. Ishiguro, University of Victoria
Timothy C. Johnston, Murray State University
Brian Jones, Genencor International B. V,Leiden, The Netherlands
Jason A. Kahana, Harvard Medical School
Suzanne V Kelly, Scottsdale Community College
Susan Koval, University of Western Ontario
Robert G. Kranz, Washington University
Brian Lanoil, Oregon State University
Martine Legrand, Dunod Editeur, Paris
Le Ma, Harvard University
John C. Makemson, Florida International University
Renee D. Mastrocco, Rockefeller University Archives
Michael McGlananan, Florida International University
Diane McGovern, Roche Molecular Systems
Ortwin Meyer, Universität Bayreuth, Germany
Cindy Morris, INRA, Station de Pathologie Vegetale, Montfavet, France
Edward Moticka, Southern Illinois University
Miklos Miiller, Rockefeller University
Dianne K. Newman, Princeton University
Aharon Oren, Hebrew University, Jerusalem
Jörg Overmann, University of Oldenburg, Germany
Norman R. Pace, University of Colorado
Cathy Patton, Molecular Probes, Inc., Eugene, OR
Norbert Pfennig, University of Konstanz, Germany
Hans Paerl, University of North Carolina
Suzette Pereira, Ohio State University
Sue Pollicott, Finnfeeds International, England
Kirsten Price, Harvard University
Reinhard Rachel, University of Regensburg, Germany
D. J. Read, University of Sheffield, England
John N. Reeve, Ohio State University
Hans Reichenbach, Gesellschaft für Biotechnologie, Braunschweig, Germany
Gary P Roberts, University of Wisconsin
Lesley Robertson, Technical University of Delft, The Netherlands
Bernhard Schink, University of Konstanz, Germany
James Shapiro, University of Chicago
Helen Shio, Rockefeller University
Pamela A. Silver, Harvard Medical School
Jolynn E Smith, Southern Illinois University
Jiri Snaidr, University of Munchen, Germany
Barton Spear, Spear Studio, Erie, PA
Stefan Spring, Universit&#228t München, Germany
Gary Stacy, University of Tennessee
David A. Stahl, Northwestern University
Karl O. Stetter, University of Regensburg, Germany
Philip S. Stewart, Montana State University
Karthikeyan Subramanian, University of Saskatchewan
Hideto Takami, Japan Marine Science and Technology Center, Kanagawa
Nancy Trun, National Institutes of Health
David M. Ward, Montana State University
Kounosuke Watabe, Southern Illinois University
Fritz Widdel, Max Planck Institute of Marine Microbiology, Germany
Carl R. Woese, University of Illinois
John Vercillo, Southern Illinois University
Stephen H. Zinder, Cornell University

In addition to those listed above, the photo credits aside each photo in this book lists those who provided the photograph. Special thanks go to Lesley Robertson and the Kluyver Laboratory Museum, Technical University of Delft, The Netherlands, for sharing with us the wonderful illustrative materials about the scientific life of Martinus Beijerinck (see for example, the front and back cover).

Finally, the authors are grateful to all the people at Prentice Hall who have contributed in significant ways to this edition, including in particular Linda Schreiber and David K. Brake (editorial), and Debra Wechsler (production). It was through Linda's strong efforts that the art program was revamped, and the authors are very grateful for her foresight in this regard. Debra deserves high praise for her professionalism in all aspects of this book and was simply a pleasure to work with—the appearance of the final product owes much to Debra's efforts. We also wish to acknowledge the contributions of Jane Loftus (Clackamas, OR) to copyediting, Robie Grant (Hadley, MA), who composed the index, and Toni Huppert, Southern Illinois University, for her expert word processing skills.

Michael T. Madigan (
Author of Chapters 1-5 and 11-17, and
BBOM 9/e coordinator
John M. Martinko (
Author of Chapters 18-24
Jack Parker (
Author of Chapters 6-10

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Table of Contents

Ch. 1 Introduction: An Overview of Microbiology and Cell Biology 1
Ch. 2 Cell Chemistry 31
Ch. 3 Cell Biology 52
Ch. 4 Nutrition and Metabolism 109
Ch. 5 Microbial Growth 149
Ch. 6 Macromolecules and Molecular Genetics 178
Ch. 7 Regulation of Gene Expression 226
Ch. 8 Viruses 248
Ch. 9 Microbial Genetics 304
Ch. 10 Genetic Engineering and Biotechnology 357
Ch. 11 Microbial Growth Control 397
Ch. 12 Industrial Microbiology 430
Ch. 13 Metabolic Diversity among the Microorganisms 473
Ch. 14 Microbial Ecology 532
Ch. 15 Microbial Evolution, Systematics, and Taxonomy 606
Ch. 16 Prokaryotic Diversity: Bacteria 635
Ch. 17 Prokaryotic Diversity: Archaea 741
Ch. 18 Eukarya: Eukaryotic Microorganisms 769
Ch. 19 Host-Parasite Relationships 785
Ch. 20 Concepts of Immunology 813
Ch. 21 Clinical and Diagnostic Microbiology and Immunology 865
Ch. 22 Epidemiology and Public Health Microbiology 902
Ch. 23 Major Microbial Diseases 929
Appendix 1 Energy Calculations in Microbial Bioenergetics A-1
Appendix 2 Advanced Mathematics of Microbial Growth and Chemostat Operation A-5
Appendix 3 Bergey's Classification of Prokaryotes A-7
Glossary G-1
Index I-1
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