BRS Physiology Cases and Problems (Board Review Series) / Edition 1

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This case-based question and problem book encourages the medical student to integrate, to problem solve and to think critically. Organized by body system, each chapter provides case studies, questions and problems followed by complete explanations and solutions including diagrams, graphs and charts. Contains most relevant medical physiology and pathophysiology information, and an integration of complex information across the organ systems. Helpful for traditional course material as well as a valuable tool for a clinical vignette review in preparation for the USMLE Step 1 exam.
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Editorial Reviews

Doody's Review Service
Reviewer: Robert W. Teel, PhD (Loma Linda University)
Description: This book consists of clinical cases organized according to organ systems followed by questions and problems that draw from the student an understanding of important physiological concepts. Questions and problems are followed by explanations that often include drawings, graphs, and flow diagrams for conciseness and clarification of concepts. As organized, this book can complement any physiology textbook or course syllabus.
Purpose: The purpose is to complement lectures, course syllabi, and textbooks of physiology with the study of clinical cases. The questions and problems emphasize elements of physiology and pathophysiology that should enrich the understanding of the relevance of physiology to the practice of medicine. The author's objectives for the book are appropriate and well met. The book can be helpful not only in understanding medical physiology but also in preparation for USMLE part I.
Audience: The book is written for first and second year medical students who are studying physiology. Background information helpful to first year students is provided. This is designed to be a working book, as the author states, to challenge its users to a better understanding of physiological concepts. The author does not have the stature of authors of major medical physiology texts such as Guyton, Berne, and Levy, but is a credible writer of books that concisely organize physiological concepts into a form that is student friendly. The author's contributions are geared more toward helping students understand the important physiological concepts to pass USMLE part I rather than presenting a detailed, authoritative textbook for a resident or specialist.
Features: By design the book has limited coverage but manages through clinical cases, related questions, and problems to cover the major organ systems. The book meets rather well the specific goals for which it is written and provides a user friendly framework for achieving those goals. The simplified drawings, use of boldface print, key points lists, and straightforward style are examples of the user friendly format. The abbreviations and normal clinical blood values listed inside the front and back covers are useful and appropriately placed. The book will serve a useful place in the education of medical students, not only in preparing them for USMLE part I but also in helping them understand the relevance of physiology to clinical practice.
Assessment: There are a number of study guides that purport to aid the medical student prepare for the USMLE step I exam, such as Physiology: PreTest Self-Assessment and Review by Ryan and Tuma (McGraw-Hill, 1999); Case Studies in Physiology by Berne and Levy (Mosby, 1994). This book is better organized to facilitate learning through the use of drawings, graphs, and flow diagrams. It is a useful supplement to medical physiology texts and might be even more useful if page references were made to these texts so that students could readily find more detailed information.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780781724821
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 6/1/1901
  • Series: Board Review Series
  • Edition description: Older Edition
  • Edition number: 1
  • Pages: 352
  • Product dimensions: 6.42 (w) x 10.50 (h) x 0.48 (d)

Meet the Author

Linda S. Costanzo, Ph.D.,Professot of Physiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia.
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Table of Contents

1 Cellular and Autonomic Physiology 1
Case 1 Permeability and Simple Diffusion 2
Case 2 Osmolarity, Osmotic Pressure, and Osmosis 7
Case 3 Nernst Equation and Equilibrium Potentials 15
Case 4 Primary Hypokalemic Periodic Paralysis 22
Case 5 Epidural Anesthesia: Effect of Lidocaine on Nerve Action Potentials 28
Case 6 Myasthenia Gravis: Neuromuscular Transmission 32
Case 7 Pheochromocytoma: Effects of Catecholamines 36
Case 8 Shy-Drager Syndrome: Central Autonomic Failure 43
2 Cardiovascular Physiology 49
Case 9 Essential Cardiovascular Calculations 50
Case 10 Ventricular Pressure-Volume Loops 59
Case 11 Responses to Changes in Posture 66
Case 12 Cardiovascular Responses to Exercise 71
Case 13 Renovascular Hypertension: The Renin-Angiotensin-Aldosterone System 78
Case 14 Hypovolemic Shock: Regulation of Blood Pressure 83
Case 15 Primary Pulmonary Hypertension: Right Ventricular Failure 91
Case 16 Myocardial Infarction: Left Ventricular Failure 98
Case 17 Atrioventricular Conduction Block 104
3 Respiratory Physiology 109
Case 18 Essential Respiratory Calculations: Lung Volumes, Dead Space, and Alveolar Ventilation 110
Case 19 Essential Respiratory Calculations: Gases and Gas Exchange 117
Case 20 Ascent to High Altitude 123
Case 21 Asthma: Obstructive Lung Disease 128
Case 22 Chronic Obstructive Pulmonary Disease 139
Case 23 Interstitial Fibrosis: Restrictive Lung Disease 147
Case 24 Carbon Monoxide Poisoning 155
4 Renal and Acid-Base Physiology 159
Case 25 Essential Calculations in Renal Physiology 160
Case 26 Essential Calculations in Acid-Base Physiology 169
Case 27 Glucosuria: Diabetes Mellitus 176
Case 28 Hyperaldosteronism: Conn's Syndrome 184
Case 29 Central Diabetes Insipidus 192
Case 30 Syndrome of Inappropriate ADH 200
Case 31 Metabolic Acidosis: Diabetic Ketoacidosis 204
Case 32 Metabolic Acidosis: Diarrhea 212
Case 33 Metabolic Alkalosis: Vomiting 218
Case 34 Respiratory Acidosis: Chronic Obstructive Pulmonary Disease 225
Case 35 Respiratory Alkalosis: Hysterical Hyperventilation 229
5 Gastrointestinal Physiology 233
Case 36 Malabsorption of Carbohydrates: Lactose Intolerance 234
Case 37 Peptic Ulcer Disease: Zollinger-Ellison Syndrome 239
Case 38 Secretory Diarrhea: Escherichia coli Infection 246
Case 39 Bile Acid Deficiency: Ileal Resection 252
6 Endocrine and Reproductive Physiology 259
Case 40 Galactorrhea and Amenorrhea: Prolactinoma 260
Case 41 Hyperthyroidism: Graves' Disease 265
Case 42 Hypothyroidism: Autoimmune Thyroiditis 273
Case 43 Adrenocortical Excess: Cushing's Syndrome 279
Case 44 Adrenocortical Insufficiency: Addison's Disease 286
Case 45 Congenital Adrenal Hyperplasia: 21 [beta]-Hydroxylase Deficiency 291
Case 46 Primary Hyperparathyroidism 297
Case 47 Hypercalcemia of Malignancy 303
Case 48 Hyperglycemia: Type I Diabetes Mellitus 309
Case 49 Primary Amenorrhea: Testicular Feminizing Syndrome 315
Case 50 Male Hypogonadism: Kallmann's Syndrome 319
Appendix 323
Index 325
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This book was written for first- and second-year medical students who are studying physiology and pathophysiology. In the framework of cases, the book covers clinically relevant topics in physiology by asking students to answer open-ended questions and solve problems. This book is intended to complement lectures, course syllabi, and traditional textbooks of physiology.

The chapters are arranged according to organ system, including cellular and autonomic, cardiovascular, respiratory, renal and acid-base, gastrointestinal, and endocrine and reproductive physiology. Each chapter presents a series of cases followed by questions and problems that emphasize the most important physiologic principles. The questions require students to perform complex, multistep reasoning and to think integratively across the organ systems. The problems emphasize clinically relevant calculations. Each case and its accompanying questions and problems are immediately followed by complete, stepwise explanations or solutions, many of which include diagrams, classic graphs, and flowcharts.

This book includes a number of features to help students master the principles of physiology.

  • Cases are shaded for easy identification.
  • Within each case, questions are arranged sequentially so that they intentionally build upon each other.
  • The difficulty of the questions varies from basic to challenging, recognizing the progression that most students make.
  • When a case includes pharmacologic or pathophysiologic content, brief background is provided to allow first-year medical students to answer the questions.
  • Major equations are presented in boldface type, followed by explanations of all terms.
  • Key topics are listed at the end of each case so that students may cross-reference these topics with indices of physiology texts.
  • Common abbreviations are presented on the inside front cover, and normal values and constants are presented on the inside back cover.
Students may use this book alone or in small groups. Either way, it is intended to be a dynamic, working book that challenges its users to think more critically and deeply about physiologic principles. Throughout, I have attempted to maintain a supportive and friendly tone that reflects my own love of the subject matter.

I welcome your feedback, and look forward to hearing about your experiences with the book. Best wishes for an enjoyable journey!

Linda S. Costanzo, Ph.D.

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