Bull's-Eye: Unraveling the Medical Mystery of Lyme Disease, Second Edition / Edition 2

Bull's-Eye: Unraveling the Medical Mystery of Lyme Disease, Second Edition / Edition 2

by Jonathan A. Edlow
     
 

ISBN-10: 0300103700

ISBN-13: 9780300103700

Pub. Date: 04/10/2004

Publisher: Yale University Press

This fascinating book not only tells the history of the discovery of Lyme disease over centuries and continents but also provides the latest information about the disease and its treatment. In the process it offers revealing details about the medical process: how physicians make a diagnosis, how they test its accuracy, and how scientific inquiry is influenced

Overview

This fascinating book not only tells the history of the discovery of Lyme disease over centuries and continents but also provides the latest information about the disease and its treatment. In the process it offers revealing details about the medical process: how physicians make a diagnosis, how they test its accuracy, and how scientific inquiry is influenced by its cultural context. Dr. Jonathan Edlow begins his detective story in Lyme, Connecticut, with the accounts of two housewives who in the mid-1970s noticed a baffling array of symptoms afflicting members of their families and others in the community. As physicians studied this strange disease, they were led to reports of similar symptoms in other eras and countries. Edlow chronicles how connections were ultimately established between symptoms and tick bites, leading to the discovery of the stages of the disease, its specific microbial cause, and its treatment. And he brings the story into the twenty-first century by discussing legal and legislative issues as well as factors that have led to recent widespread outbreaks of Lyme disease and to the controversies over its diagnosis, vaccine, treatment, and even its very definition.

Product Details

ISBN-13:
9780300103700
Publisher:
Yale University Press
Publication date:
04/10/2004
Edition description:
Second Edition
Pages:
308
Product dimensions:
6.13(w) x 9.25(h) x (d)

Table of Contents

Preface to the Second Editionix
Prefacexiii
Acknowledgmentsxvi
Chronologyxviii
1A Family Under Siege1
2A Little Girl's Knee9
3The Broad Street Pump17
4An Appointment in New Haven28
5An Outbreak of Arthritis36
6An Outbreak of Dermatitis46
7The European Connection55
8Further Work in Europe62
9The Blind Men and the Elephant72
10The Connection with Ticks81
11An Intersection of Investigations90
12From the Alps to the Rockies102
13To Treat or Not to Treat?110
14The Scramble for the Cause118
15The Culmination of Efforts130
16Progress to the End of the 1980s141
17A Geographical Expansion150
18The Diagnostician's Dilemma160
19Ambiguity in the Lab170
20A Tick with Two Toxins179
21Cracks in the Theory188
22Another Paradigm199
23Therapeutic Adventures212
24Genomes and Vaccines221
25Legal and Political Battles231
26An Independent Reality243
Epilogue251
Appendix255
ASymptoms of Lyme Disease255
BTick-Borne Diseases in Humans and Animals256
Sources259
Glossary275
Index279

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