Calcium in Human Health / Edition 1

Calcium in Human Health / Edition 1

by Connie M. Weaver
     
 

Calcium performs diverse biological functions in the human body and is a micronutrient essential to human health and well-being. It serves as a second messenger for nearly every biological process, stabilizes many proteins, and in deficient amounts is associated with a large number diseases and disorders. In Calcium in Human Health, a panel of highly respected

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Overview

Calcium performs diverse biological functions in the human body and is a micronutrient essential to human health and well-being. It serves as a second messenger for nearly every biological process, stabilizes many proteins, and in deficient amounts is associated with a large number diseases and disorders. In Calcium in Human Health, a panel of highly respected researchers and clinical practitioners comprehensively reviews the state of our knowledge concerning this ubiquitous micronutrient, not only demonstrating its importance to human health, but also defining its many complex roles. The authors summarize the latest basic scientific information on the cellular and metabolic functions of calcium, explaining the leading techniques for accurately measuring its bioavailability, absorption, and kinetics, and showing that calcium deficiency is a major problem while calcium excess a rare one. They also examine the complex regulation of calcium absorption, distribution, and excretion, as well as the multiple interactions of diet, lifestyle, and physical activity in calcium homeostasis. Their discussion of the specific roles of calcium in a variety of clinical disorders-osteoporosis, oral health, obesity, reproductive disorders, and the metabolic syndrome-provides new insights and raises new questions. The complex changes in calcium and phosphate regulation that occur in renal disease and the potential role of calcium in hypertension and vascular disease are also addressed.

Comprehensive and authoritative, Calcium in Human Health offers health professionals and researchers a vast amount of current information on the sources, biological function, interactions, and disease implications of calcium, a critical benchmark resource for improving the health outcomes of individuals, finding new drugs that alter the function of the extracellular calcium receptor, setting adequate dietary requirements, and developing new disease-prevention programs.

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Product Details

ISBN-13:
9781617375798
Publisher:
Springer-Verlag New York, LLC
Publication date:
11/09/2010
Series:
Nutrition and Health Series
Edition description:
Softcover reprint of hardcover 1st ed. 2006
Pages:
472
Product dimensions:
10.00(w) x 7.00(h) x 0.95(d)

Table of Contents

Introduction
Connie M. Weaver and Robert P. Heaney

I. Calcium Functions

Bone as the Calcium Nutrient Reserve
Robert P. Heaney

Cellular Functions and Fluxes of Calcium
Emmanuel M. Awumey and Richard D. Bukoski

II. Techniques for Studying Calcium Metabolism and Its Relationship to Disease

Nutritional Epidemiology: Dietary Assessment Methods
Carol J. Boushey

Clinical Approaches for Studying Calcium Metabolism and Its Relationship to Disease
Connie M. Weaver

Kinetic Studies
Meryl E. Wastney, Yongdong Zhao, and Connie M. Weaver

III. Calcium Consumption, Requirements, and Bioavailability

Requirements for What Endpoint?
Robert P. Heaney and Connie M. Weaver

Dietary Calcium: Recommendations and Intakes Around the World
Anne C. Looker

Food Sources, Supplements, and Bioavailability
Connie M. Weaver and Robert P. Heaney

IV. Calcium Homeostasis

The Calcium Economy
Robert P. Heaney

Molecular Regulation of Calcium Metabolism
James C. Fleet

Influence of Total Diet on Calcium Homeostasis
Zamzam K. (Fariba) Roughead

Influence of Lifestyle Choices on Calcium Homeostasis: Smoking, Alcohol, and Hormone Therapies
D. Lee Alekel, and Oksana Matvienko

Influence of Physical Activity on Calcium and Bone
Matthew Vukovich and Bonny Specker

The Case for a Calcium Appetite in Humans
Michael G. Tordoff

V. Calcium Through Development

Infancy and Childhood
Steven A. Abrams and Keli M. Hawthorne

Pre-Puberty and Adolescence
Connie M. Weaver

Calcium in Pregnancy and Lactation
Heidi J. Kalkwarf

VI. Calcium and Disease

Calcium in Systemic Human Health
Robert P. Heaney

Calcium and Oral Health
Elizabeth A. Krall

Dietary Calcium and Obesity
Dorothy Teegarden

Polycystic Ovary Syndrome and Reproduction
Susan Thys-Jacobs

Premenstrual Syndrome
Susan Thys-Jacobs

Calcium Throughout the Life Cycle: The Later Years
Bess Dawson-Hughes

Calcium, Vitamin D, and Cancer
Peter R. Holt

Dietary Calcium and the Metabolic Syndrome
Dorothy Teegarden

Calcium and Phosphate Control in Patients With Renal Disease
David A. McCarron and Robert P. Heaney

Hypertension and Cardiovascular Disease
David A. McCarron

Appendices

Index

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