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More About This Textbook
Overview
Cancer and the Kidney covers the challenging overlap area of nephrology and oncology. Kidney problems in cancer patients, and cancer that affects kidney patients, are both very real clinical issues in medicine. For example, cancer is a common complication of kidney transplantation, and up to half of all survivors of bone marrow transplant may develop chronic kidney disease.
Since publication of the first edition in 2005, there have been many changes in this area. These include the recognition of chronic kidney disease after uninephrectomy for cancer, the occurrence of medication toxicities of the EGFR antagonists and of the VEGF antagonists, and changes in the approach to multiple myeloma. In this new edition, the primary authors cover diverse subjects in this area, ranging from assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween. Each chapter starts with a case study to ensure a practical focus, and there are numerous illustrations throughout. Specialists and trainees in nephrology and in oncology will find it a useful starting point and reference, as will physician assistants and nurse practitioners who work in these fields.
Editorial Reviews
From The Critics
Reviewer: Mony Fraer, MD, FACP, FASN(University of Iowa Hospitals and Clinics)Description: Coming six years after the first edition, this is a necessary update of a book spanning the frontier of nephrology and oncology. The book has expanded to 360 pages and now it includes two new chapters on biologics and their effects (including toxicities of the EGFR and VEGF antagonists) and bone marrow transplant.
Purpose: It presents data and observations on cancer conditions of the kidney (as well as cancer as a complication of kidney transplantation) and how other cancers and treatments (including stem cell transplant) affect the kidney. The international authors keep the book's clinical focus: each chapter starts with a case study and poses relevant clinical questions, like when should we screen for kidney cancer and how can we identify patients at risk, and how to work up incidentally discovered cysts in the kidney.
Audience: The book is written for specialists and trainees in nephrology and oncology, but all practitioners in these fields would enjoy and benefit from reading it.
Features: The content is well organized, succinct yet inclusive. The book discusses acute renal failure, chronic kidney disease, end-stage renal disease, and renal transplantation. Other important topics in this area include: fluid and electrolyte disorders associated with cancer, radiation nephropathy and urinary tract obstruction in cancer patients. The references are up to date and the index is well organized.
Assessment: The discussion of malignancy-associated glomerulopathies is very comprehensive and I also liked the chapter on paraneoplastic glomerulopathies. The most exciting part of the book is the information on developments in cancer biology and the new treatments that are available — antibodies and agents with new targets. There are some histologic and radiologic images but the book would benefit from more and better images.s.
Product Details
Meet the Author
This book reflects Dr Cohen's active interest in the challenging overlap area of nephrology and oncology, deriving in turn from his interest and multiple studies of kidney disease after hematopoietic stem cell transplant ("bone marrow transplant"). He trained at the Universite de Liege, in Belgium and is a member of the Central Society for Clinical Research, the American Society of Nephrology, the Societe Francophone de Dialyse, and the Radiation Research Society. His research bridges the clinic and the lab, bringing the best of each to the other.
Table of Contents
1. The assessment of kidney function
2. Fluid and electrolyte disorders associated with cancer
3. Paraneoplastic glomerulopathies
4. Paraproteins and the kidney
5. Nephrotoxicity of chemotherapy agents and chemotherapy administration in patients with renal disease
6. Biological cancer therapies and the kidney
7. Radiation nephropathy
8. Renal complications of hematopoietic stem cell transplantation
9. Acute renal failure in cancer patients
10. Urinary tract obstruction in cancer patients
11. Acquired cysts and cancer of failing kidneys
12. Kidney cancer
13. Cancer after renal transplantation