Cancer Chemotherapy: Concepts, Clinical Investigations and Therapeutic Advances / Edition 1

Cancer Chemotherapy: Concepts, Clinical Investigations and Therapeutic Advances / Edition 1

by Franco M. Muggia
     
 

ISBN-10: 0898383811

ISBN-13: 9780898383812

Pub. Date: 11/30/1988

Publisher: Springer US

Product Details

ISBN-13:
9780898383812
Publisher:
Springer US
Publication date:
11/30/1988
Series:
Cancer Treatment and Research Series, #42
Edition description:
1989
Pages:
238
Product dimensions:
6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

I. Concepts.- 1. Alkylating agents: Mechanisms and modulation.- 2. Reduced folates and fluoropyrimidine antitumor efficacy.- 3. Laboratory aspects of multidrug resistance.- II. Initial clinical investigations.- 4. Multidrug resistance: clinical findings and implications.- 5. Current status of trimetrexate, a folate antagonist with antineoplastic and antiprotozoal properties.- 6. Daunomycin and doxorubicin LYM-1-drug conjugates for the treatment of malignant lymphomas.- 7. Phase I trials: Role of the nurse investigator.- III. Therapeutic advances.- 8. The role of chemotherapy in the treatment of squamous cell tumors of the esophagus.- 9. Systemic chemotherapy of transitional cell carcinoma of the urothelium.- 10. Nasopharyngeal cancer, undifferentiated type: The medical oncologist’s viewpoint.- 11. Primary central nervous system lymphomas.

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