Cancer Chemotherapy: Concepts, Clinical Investigations and Therapeutic Advances / Edition 1

Hardcover (Print)
Buy New
Buy New from
Used and New from Other Sellers
Used and New from Other Sellers
from $209.81
Usually ships in 1-2 business days
(Save 27%)
Other sellers (Hardcover)
  • All (7) from $209.81   
  • New (6) from $209.81   
  • Used (1) from $340.02   

Editorial Reviews

Focus of these articles is on new advances such as the current status of trimetrexate, the ability to modulate the action of alkylating agents and fluorinated pyrimidines to achieve greater sensitivity, and the genetics of multidrug resistance in human tumors. Also addressed are the role of the nurse investigator, and four evolving targets of chemotherapy. Annotation c. Book News, Inc., Portland, OR (
Read More Show Less

Product Details

  • ISBN-13: 9780898383812
  • Publisher: Springer US
  • Publication date: 11/30/1988
  • Series: Cancer Treatment and Research Series, #42
  • Edition description: 1989
  • Edition number: 1
  • Pages: 252
  • Product dimensions: 9.21 (w) x 6.14 (h) x 0.63 (d)

Table of Contents

I. Concepts.- 1. Alkylating agents: Mechanisms and modulation.- 2. Reduced folates and fluoropyrimidine antitumor efficacy.- 3. Laboratory aspects of multidrug resistance.- II. Initial clinical investigations.- 4. Multidrug resistance: clinical findings and implications.- 5. Current status of trimetrexate, a folate antagonist with antineoplastic and antiprotozoal properties.- 6. Daunomycin and doxorubicin LYM-1-drug conjugates for the treatment of malignant lymphomas.- 7. Phase I trials: Role of the nurse investigator.- III. Therapeutic advances.- 8. The role of chemotherapy in the treatment of squamous cell tumors of the esophagus.- 9. Systemic chemotherapy of transitional cell carcinoma of the urothelium.- 10. Nasopharyngeal cancer, undifferentiated type: The medical oncologist’s viewpoint.- 11. Primary central nervous system lymphomas.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)