Cancer: Basic Science and Clinical Aspects [NOOK Book]


While intended primarily for non-majors, this forward looking cancer biology book will appeal to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters will bring unprepared students up to speed for the rest of the book and will serve as a useful refresher for those with previous biology background. The second set of chapters will focus on the main cancers in terms of risk factors, diagnostic and ...
See more details below
Cancer: Basic Science and Clinical Aspects

Available on NOOK devices and apps  
  • NOOK Devices
  • Samsung Galaxy Tab 4 NOOK
  • NOOK HD/HD+ Tablet
  • NOOK
  • NOOK Color
  • NOOK Tablet
  • Tablet/Phone
  • NOOK for Windows 8 Tablet
  • NOOK for iOS
  • NOOK for Android
  • NOOK Kids for iPad
  • PC/Mac
  • NOOK for Windows 8
  • NOOK for PC
  • NOOK for Mac
  • NOOK for Web

Want a NOOK? Explore Now

NOOK Book (eBook)
$58.99 price
(Save 42%)$102.95 List Price
Note: This NOOK Book can be purchased in bulk. Please email us for more information.


While intended primarily for non-majors, this forward looking cancer biology book will appeal to a wide ranging audience. Introductory chapters that provide the molecular, cellular, and genetic information needed to comprehend the material of the subsequent chapters will bring unprepared students up to speed for the rest of the book and will serve as a useful refresher for those with previous biology background. The second set of chapters will focus on the main cancers in terms of risk factors, diagnostic and treatment methods and relevant current research. The final section will encompass the immune system's role in the prevention and development of cancer and the impact that the Human Genome Project will have on future approaches to cancer care. The text is strategically inclusive of pedagogical features that will assist students in both study and comprehension while illustrating real life application of the concepts.
Read More Show Less

Product Details

  • ISBN-13: 9781444357394
  • Publisher: Wiley
  • Publication date: 8/26/2011
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 1
  • Pages: 424
  • Sales rank: 1,295,301
  • File size: 5 MB

Meet the Author

Sheila Barry and Craig Almeida have taught the cancer biology course at Stonehill College to both majors and non-majors for several years. Discouraged by the lack of accessible and current texts, they decided to write their own.
Read More Show Less

Table of Contents



1. The Basics of Cancer.

Cancer is a Complex Entity.

Cancer Through the Ages.

Modern Day Cancer Research and Treatment.

Prevalence and Mortality Varies With Each Cancer.

Risk Factors Have Been Identified.

Will Cancer be Conquered Within Our Lifetime?

2. Cells: the Fundamental Unit of Life.

Seven Hierarchal Levels of Organization.

Four Types of Macromolecular Polymers.

Cell Structure and Function.

Relationship Between Structure and Function is Important.

3. The Human Genome and Protein Function.

The Composition and Function of the Human Genome.

Having a Diploid Genome has its Advantages.

Proteins Carry Out Diverse Functions.

4. Cell Cycle, Oncogenes, and Tumor Suppressor Genes.

Cell Division in Germ-line and Somatic Tissues.

Consequences of Germ-line and Somatic Tissue Mutations.

Cell Division, Differentiation, and Maturation Occur to Form Functional Tissues.

Cell Division is Under the Regulation of the Cell Cycle.

Loss of Cell Cycle Control Results in Uncontrolled Cell Growth.

5. Tumor Formation, Growth, and Metastasis.

Tissue Changes that Occur in Response to Stimuli.

Feeding Tumor Growth by Angiogenesis.

Characteristics of Benign and Malignant Tumors.

Events that Occur During the Process of Metastasis.

6. Cancer Screening, Detection and Diagnostic Procedures and Tests.

Factors that Determine the Accuracy of a Diagnostic Test or Procedure.

Common Screening Tests.

Diagnostic Procedures for the Confirmation of a Disease.

Tumor Grade and Stage Factors into the Type of Treatment Regimen and Prognosis.

7. Cancer Treatment Modalities.

Surgery: the Oldest and Most Commonly Used Treatment Method.

Radiation Kills by Causing Extensive DNA Damage.

Cytotoxic Effects of Chemotherapeutic Drugs.

Side Effects and Risks From the Use of Cytotoxic Drugs.

Hormonal Deprivation Treatment: Used for Estrogen- and Androgen-dependent Cancers.

Can Cancer Growth be Controlled by Inhibiting Angiogenesis?

Additional Enzymes Targeted for Inhibition.

Biological Therapy Stimulates the Body’s Ability to Fight Cancer.

8. Breast Cancer.

Breast Cancer Statistics.

Women’s Breast Tissue: Unique in Structure and Function.

Causes of Breast Cancer.

Regular Examinations of the Breast are Important for Early Diagnosis.

What Follows a Positive Diagnosis?

Treatment Options are Unique for Each Individual.

Much has Been Accomplished, More Needs to be Done.

9. Ovarian Cancer.

Ovarian Cancer Statistics.

Structure and Function of Ovaries.

There are Three Tissue Categories of Ovarian Cancer.

Symptoms are Vague and Often Missed.

Certain Factors Have Been Associated with a Higher Risk.

Diagnostic Tools are Available But Not Always Used or Recommended.

Additional Procedures are Necessary to Confirm Suspicious Results or if there is Metastasis.

The FIGO System May be Used to Stage Ovarian Cancer.

Treatment Options for Ovarian Cancer.

Steps are Taken to Prevent Recurrence But Do Not Always Work When the Cancer is Advanced.

Much Needs to be Done in the Future.

10. Cervical Cancer.

Cervical Cancer Statistics.

Structure and Function of the Cervix.

Symptoms of Cervical Cancer.

Pelvic Examinations and Pap Tests Enable Early Detection.

Risk Factors for Cervical Cancer.

The HPV Test is a Vital Diagnostic Tool.

Additional Tests are Necessary to Examine the Cervix.

Treatment Depends on the Stage.

A Vaccine will Prevent Many Cases of Cervical Cancer.

11. Prostate Cancer.

Prostate Cancer Statistics.

Function of the Prostate Gland.

Certain Factors Influence the Development of Prostate Cancer.

Symptoms of an Enlarged Prostate.

Screening and Diagnostic Tests for Prostate Cancer.

There are Traditional and Unique Treatment Options Available.

Prostate Cancer Mortality Rates Have Decreased.

Much Attention is being Given to the Number One Cancer Affecting Men.

12. Testicular Cancer.

Testicular Cancer Statistics.

Structure and Function of Testicles.

There are Three Types of Testicular Tumors.

Risk Factors for the Disease.

Symptoms of Testicular Cancer.

Testicular Self-examination (TSE) is Recommended.

Blood and Imaging Tests are Used to Determine Diagnosis and Possible Metastasis.

Testicular Cancer Treatment Results in a High Cure Rate.

Causes and Treatments are being Studied.

13. Skin Cancer.

Skin Cancer Statistics.

Structure and Function of the Skin.

Three Types of Skin Cancer.

Risk Factors for Developing Skin Cancer.

Methods Used to Screen for Skin Cancer.

Surgery and Chemotherapy are Standard Treatments for Metastatic Skin Cancer.

What Happens After Skin Cancer Treatment.

Limited UV Radiation Exposure is the Number One Form of Prevention.

14. Lung Cancer.

Lung Cancer Statistics.

Lungs are the Site of the Exchange of Gases.

Risk Factors Associated with the Development of Lung Cancer.

Lack of Distinctive Symptoms Makes Early Diagnosis Difficult.

Lung Cancer is Often Diagnosed at an Advanced Stage.

There are Two Main Categories of Lung Cancer.

Three Traditional Therapies are Used in Lung Cancer Treatment.

Is There Discrimination in Cancer Research Funding?

15. Colorectal Cancer.

Colon and Rectum are the Last Two Sections of the Gastrointestinal Tract.

Risk Factors for Colorectal Cancer.

Screening Tests.

Treatment Options.

Targeted Therapies.

Screening Tests Performed After the Course of Treatment.

16. Leukemia and Lymphoma.

Leukemia Statistics.

Leukemia is a Cancer of the Blood Cells.

The Exact Cause of Leukemia is Unknown.

Early Symptoms of Leukemia.

Laboratory Studies are Necessary to Determine the Diagnosis.

There are Many Types of Leukemia.

Nonchemotherapeutic Options have Significantly Improved Survival Rates.

Lymphoma is a Malignancy of the Lymphatic System.

Hodgkin’s vs. Non-Hodgkin’s lymphoma.

Certain Risk Factors are Associated with an Increased Incidence of Lymphoma.

Diagnosing Lymphoma Involves Biopsies and Imaging Tests.

Lymphomas Must be Classified to Determine Appropriate Treatment.

Treatment Options Depend on the Type of Lymphoma, Stage, and Extent of Metastasis.



Companion website

Read More Show Less

Customer Reviews

Average Rating 5
( 1 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously
Sort by: Showing 1 Customer Reviews
  • Anonymous

    Posted March 4, 2014

    No text was provided for this review.

Sort by: Showing 1 Customer Reviews

If you find inappropriate content, please report it to Barnes & Noble
Why is this product inappropriate?
Comments (optional)