Cancer Cytogenetics / Edition 3

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The preeminent book on cancer cytogenetics-now in a valuable new edition

The book contains black-and-white illustrations.

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Editorial Reviews

A description of neoplastic processes at the chromosomal level of genomic organization. Opens with a summary of cytogenetic methods and terminology, reviews key aspects of chromosomal abnormalities in cancer, then discusses the karyotypic and molecular genetic characteristics of specific neoplastic disorders and their clinical implications. A resource for clinicians working with cancer patients and for researchers in cytogenetics, medical and molecular genetics, cellular and molecular biology, oncology, and hematology. Annotation c. Book News, Inc., Portland, OR
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Product Details

  • ISBN-13: 9780470181799
  • Publisher: Wiley
  • Publication date: 5/4/2009
  • Edition description: New Edition
  • Edition number: 3
  • Pages: 756
  • Sales rank: 1,508,385
  • Product dimensions: 7.00 (w) x 12.10 (h) x 1.50 (d)

Meet the Author

Professor Sverre Heim has worked within the field of cancer cytogenetics for more than three decades. He has used chromosomal markers to trace the clonal relationships among neoplastic cell populations and determine their patterns of evolution. He has described numerous specific chromosome abnormalities in various hematologic disorders and solid tumors, identified their gene-level consequences, and has shown that the karyotypic and molecular genetic abnormalities have diagnostic as well as prognostic consequences. Dr Heim has served as a member of several editorial boards and scientific advisory committees. He is the author of nearly 500 scientific publications.

Professor Felix Mitelman has published more than 750 articles in the field of cancer cytogenetics. In the early 1980s, he established a unique database on chromosome changes in cancer – a systematic compilation of reported acquired cytogenetic aberrations, the molecular genetic outcome of the cytogenetic abnormalities, and the clinical consequences of the genetic changes. In 1989, Dr Mitelman founded the journal Genes, Chromosomes & Cancer and he has since served as the Editor-in-Chief. He is an elected member of several distinguished societies, including the Royal Swedish Academy of Sciences and the American Academy of Arts and Sciences.

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Table of Contents

Preface to the Second Edition
Preface to the First Edition
Ch. 1 A New Approach to an Old Problem 1
Ch. 2 Cytogenetic Methods and Terminology 7
Ch. 3 Nonrandom Chromosome Abnormalities in Cancer - An Overview 19
Ch. 4 Chronic Myeloid Leukemia 33
Ch. 5 Acute Myeloid Leukemia 69
Ch. 6 Myelodysplastic Syndromes 141
Ch. 7 Chronic Myeloproliferative Disorders 166
Ch. 8 Acute Lymphoblastic Leukemia 180
Ch. 9 Chronic Lymphoproliferative Disorders 237
Ch. 10 Malignant Lymphomas 266
Ch. 11 Tumors of the Respiratory Tract 310
Ch. 12 Tumors of the Digestive Tract 325
Ch. 13 Tumors of the Urinary Tract 350
Ch. 14 Tumors of the Breast 369
Ch. 15 Tumors of the Female Genital Organs 389
Ch. 16 Tumors of the Male Genital Organs 408
Ch. 17 Tumors of the Endocrine Glands 422
Ch. 18 Tumors of the Nervous System 432
Ch. 19 Tumors of the Eye 455
Ch. 20 Tumors of the Skin 465
Ch. 21 Tumors of Bone and Soft Tissue 476
Index 514
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